[Influencing Factors and Significance of Tumor-associated Macrophage Polarization in Tumor Microenvironment]. [PDF]
Zhongguo Fei Ai Za Zhi, 2023 Ge W, Wu W.
europepmc +1 more source
Zhongguo shiyan zhenduanxue目的 探究Dectin-1通过巨噬细胞极化影响STEMI的机制研究。方法 将45只SPF级SD大鼠随机分为假手术组(n=15)、模型组(n=15)、si-Dectin-1组(n=15),模型组与si-Dectin-1组分别通过尾静脉注射NC-质粒和si-Dectin质粒，2周后建立ST段抬高型心肌梗死(ST-Segment Elevation Myocardial Infarction, STEMI)模型，2周后分离心脏组织，qPCR检测心脏组织Dectin-1表达水平，TTC染色检测心肌坏死面积 ...
孙倩, 苏艳, 张雅兰, 李晓林
doaj
Nanosilver alleviates foreign body reaction and facilitates wound repair by regulating macrophage polarization. [PDF]
J Zhejiang Univ Sci B, 2023 You C +5 more
europepmc +1 more source
[Research progress on the regulation of macrophage polarization by mechanical stimulation in wound healing]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, 2022 Xu C, Yu D, Zhu H.
europepmc +1 more source
[Oral Squamous Cell Carcinoma-Derived Cell-Free DNA Modulates Stemness and Migration of Oral Squamous Cell Carcinoma Cell Line by Inducing M2 Macrophage Polarization]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue Ban, 2023 Zheng SZ +6 more
europepmc +1 more source
Dectin-1通过巨噬细胞极化影响STEMI的机制研究 附视频
Zhongguo shiyan zhenduanxue目的 探究Dectin-1通过巨噬细胞极化影响STEMI的机制研究。方法 将45只SPF级SD大鼠随机分为假手术组(n=15)、模型组(n=15)、si-Dectin-1组(n=15),模型组与si-Dectin-1组分别通过尾静脉注射NC-质粒和si-Dectin质粒，2周后建立ST段抬高型心肌梗死(ST-Segment Elevation Myocardial Infarction, STEMI)模型，2周后分离心脏组织，qPCR检测心脏组织Dectin-1表达水平，TTC染色检测心肌坏死面积 ...
doaj +2 more sources
[Regulatory mechanism of deferoxamine on macrophage polarization and wound healing in mice with deep tissue injury]. [PDF]
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi, 2022 Shan H +4 more
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban巨噬细胞作为心脏固有免疫系统的关键细胞，具有高度异质性和可塑性，在心脏生理和病理进程中发挥双重作用。近年，巨噬细胞源性外泌体作为细胞间通讯的重要介质，在心脏疾病中的调控机制及潜在治疗应用备受关注。本文系统总结心脏常驻巨噬细胞的起源、分布和功能，探讨M1和M2型巨噬细胞在心脏炎症反应和组织修复中的作用，以及巨噬细胞外泌体在心脏疾病中的调控机制和治疗应用前景。在心脏损伤急性阶段，M1型巨噬细胞通过分泌促炎细胞因子等引发炎症，清除细胞碎片，但过度激活会导致心肌细胞损伤和纤维化；恢复阶段，M2型巨噬细胞主导 ...
谭云科, 杨正飞
doaj
Zhongshan Daxue xuebao. Yixue kexue ban目的探讨广州管圆线虫来源的Acan-Gal-1调控巨噬细胞免疫表型和Annexin A2/S100A10膜表面易位的分子机制。方法采用IFA方法检测巨噬细胞中Annexin A2和S100A10的定位；采用流式细胞术和ELISA检测巨噬细胞功能变化；通过siRNA干扰Annexin A2，检测Acan-Gal-1对各指标的影响。通过Western blot、qRT-PCR等方法检测相关基因和蛋白的表达。通过生物信息学方法分析Acan-Gal-1蛋白结构特征，利用软件进行序列比对，预测其与Annexin ...
谢丽莎 +4 more
doaj
[SLC1A5 overexpression accelerates progression of hepatocellular carcinoma by promoting M2 polarization of macrophages]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZou J, Wang H, Zhang D.
europepmc +1 more source