Results 51 to 60 of about 1,777 (140)
急性白血病患者血清SDF-1、GM-CSF、α-HBDH的表达水平及临床意义
Zhongguo shiyan zhenduanxue, 2018 基质细胞衍生因子-1（SDF-1）可通过细胞因子的网络系统影响机体造血、免疫、血管发育等多种生理病理过程,可与CXCR4相互作用,从而对急性白血病具有促进作用[1];粒细胞-巨噬细胞集落刺激因子（GM-CSF）在早期造血阶段具有一定的光谱效应,在放化疗所致造血功能障碍恢复中具有积极作用[2]。此外,急性白血病不仅外周血以及骨髓表现异常,其酶学表达同样存在异常 ...
杨娜 +5 more
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Pathological Characteristics and Classification of Unstable Coronary Atherosclerotic Plaques [PDF]
Important forensic diagnostic indicators of sudden death in coronary atherosclerotic heart disease, such as acute or chronic myocardial ischemic changes, sometimes make it difficult to locate the ischemic site due to the short death process, the lack of ...
Yun-hong XING, Yang LI, Wen-zheng WANG, Liang-liang WANG, Le-le SUN, Qiu-xiang DU, Jie CAO, Guang-long HE, Jun-hong SUN
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Mechanism of astragaloside Ⅳ remodeling tumor immunosuppressive microenvironment [PDF]
Tumor immunosuppressive microenvironment (TIME) plays a crucial role in tumor growth and immune escape. A number of studies have found that Astragaloside Ⅳ (AS-Ⅳ) effectively reshaped TIME by reducing the expression of programmed cell death ligand 1 (PD ...
FU Nan*, ZHANG Siyue, WANG Jinhua
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Experimental study of artesunate ameliorating head-and-neck radiation-induced skin fibrosis in rats through inhibiting Stat3/TGF-β1 signaling pathway [PDF]
Objective To study the effect and mechanism of artesunate (ART) in improving radiation-induced skin fibrosis (RISF) induced by head-and-neck radiotherapy in rats. Methods Thirty Sprague-Dawley rats were randomly divided into three groups: a control group,
NONG Xiaolin, OU Jianbo, TANG Chan
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Progress in the role of exosomes in sepsis⁃induced cardiomyopathy [PDF]
"Sepsis is a life⁃ threatening organ dysfunction triggered by a dysregulated host response to infection. Sepsis⁃ induced cardiomyopathy（SICM）is an acute cardiac condition caused by sepsis，characterized by high incidence and extremely high mortality ...
ZHENG Ye*，LI Shaoling，HAN Fei
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Linchuang shenzangbing zazhi, 2014 目的 肾间质呈肉芽肿样改变是少见的病理表现,既往报道的病因多为结节病、药物、感染、结核导致的肾间质肉芽肿样改变。本研究拟了解肾间质呈肉芽肿样改变的病因、临床特点及预后。方法 回顾性分析四川省人民医院肾内科2006年7月至2013年6月共2 330例肾活检患者资料,其中肾活检组织肾小球数目大于10个的患者纳入分析。免疫组织化学染色方法标记CD3 T淋巴细胞、CD20B淋巴细胞、CD68单核巨噬细胞在肾间质的表达。结果 表现为肉芽肿样间质肾炎的8例患者占肾活检的0.34%(8/2 330),其中男女各半 ...
王蔚
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, 2019 肝脏作为体内代谢外源因素暴露最重要的器官之一,具有独特的血窦结构和丰富的免疫细胞亚群,构成了肝脏局部免疫微环境。其中,肝脏的先天免疫细胞既可通过清除病原体、抗原提呈作用参与宿主防御,还通过与肝实质细胞的相互作用参与外源因素介导的急性免疫反应、肝细胞毒性转归、慢性肝损伤以及肝致癌作用。线粒体作为细胞应激的关键靶细胞器,是整合肝脏局部免疫信号的分子互作平台,既通过线粒体质量控制精细调控细胞内的分子事件,也通过线粒体损伤相关分子模式介导不同细胞间通讯和交互作用调控免疫微环境的稳态 ...
张力引, 林忠宁, 林育纯
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Progress in the study of the role of mesenchymal stem cell exosomes in heart transplant rejection [PDF]
Heart transplantation is an effective treatment for patients with end-stage heart failure, but faces challenges such as organ shortage and rejection.
LIU Dezhao, ZENG Zhiyu
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Mechanism of Nrf2 in the treatment of ulcerative colitis via regulating macrophage polarization. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2023 Zhang Y, Liu Y, Yang S, Yan S.
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