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尿外泌体非编码RNA在糖尿病肾病发病机制及诊断中的最新研究进展

Zhongguo shiyan zhenduanxue
糖尿病肾病（diabetic kidney disease,DKD）如今占所有导致终末期肾病（end-stage renal disease ESRD）原发病的近50%[1]。目前糖尿病肾病的诊断及分期主要依靠尿微量白蛋白的检测，其缺点是敏感性和特异性相对较低，而肾穿刺活检术则操作风险较高，尚缺少采集程序无创性的理想检测标志物。外泌体是直径范围40～160nm被脂质双层膜包裹的囊泡，广泛分布于血液、尿液等体液中。尿液中的外泌体是一种易采集的非侵入性生物标志物 ...
杨文昊, 云志飞, 李倩玉, 刘锋
doaj  

[Research advances on the role of microRNA engineered exosomes in diabetic wounds]. [PDF]

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi
Jian XC, Deng CL.
europepmc   +1 more source

[<i>Qingda</i> Granules inhibit cerebral microvascular endothelial cell apoptosis in hypertensive mice by suppressing the P53 signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Lin Y, Shi S, Wang J, Lin S, Zhang J, Lin S, Chen Y, Zhang L, Cai Q.   +8 more
europepmc   +1 more source

[Chronic iron overload induces diminished ovarian reserve in mice <i>via</i> iron metabolism dysregulation-mediated oxidative stress and endocrine dysfunction]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Yu J, Chu J, Liang C.
europepmc   +1 more source

[<i>Wenyang Huazhuo Tongluo</i> Formula promotes angiogenesis in systemic sclerosis dermal microvascular endothelial cells by regulating the Sema3A/Nrp1 pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Guo K, Wang Y, Li Y, Zhang H, Han L, DU R, Ouyang J, Bian H.   +7 more
europepmc   +1 more source

尿外泌体非编码RNA在糖尿病肾病发病机制及诊断中的最新研究进展 附视频

Zhongguo shiyan zhenduanxue
糖尿病肾病（diabetic kidney disease,DKD）如今占所有导致终末期肾病（end-stage renal disease ESRD）原发病的近50%[1]。目前糖尿病肾病的诊断及分期主要依靠尿微量白蛋白的检测，其缺点是敏感性和特异性相对较低，而肾穿刺活检术则操作风险较高，尚缺少采集程序无创性的理想检测标志物。外泌体是直径范围40～160nm被脂质双层膜包裹的囊泡，广泛分布于血液、尿液等体液中。尿液中的外泌体是一种易采集的非侵入性生物标志物 ...
doaj   +2 more sources

[Fecal microbiota transplantation inhibits colonic tumor growth in mice by suppressing the TLR4/MyD88/NF-κB signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhang J, Bai J, Ren X, Ye X, Tan M, Yang Y, Li L, Fu Z.   +7 more
europepmc   +1 more source

[Targeted inhibition of miR-503 upregulates Apelin expression to alleviate myocardial infarction in mice]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Li J, He Y, Bi F, Chen J, Fan Z, Zhang Y, Chen E, Xiao H, Wu Y, Tian H, Zhou Y.   +10 more
europepmc   +1 more source

IgA肾病患者尿液外泌体中微小RNA-146a、微小RNA-210表达及与病理分级的相关性研究

Linchuang shenzangbing zazhi, 2023
陈茂丽, 常晓东, 魏书彬, 何易, 薛痕   +4 more
doaj  

[Effect of pioglitazone on periodontitis-related renal injury in mice and its relationship with Klotho]. [PDF]

Hua Xi Kou Qiang Yi Xue Za Zhi
Shang Y, Hu M, Che Z, Liu X, Deng Y, Yu W.   +5 more
europepmc   +1 more source