Protective effect and mechanism of ethanol extract of sesame on myocardial injury in rats with exercise-induced fatigue [PDF]
ObjectiveTo study the cardioprotective effect of sesame ethanol extract (SEE) on exercise-induced fatigue (EIF) rats and its effects on myocardial physiological and biochemical parameters.MethodsRats were randomly divided into control group (Control ...
LI Qiang, MAO Yufeng
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Skin Ultrastructure and the Changes of HIF-2α, H-FABP Expression in the Myocardium of Electric Shock Death Rats [PDF]
Objective To observe the skin ultrastructure change of electric shock death rats and to test the expression changes of hypoxia-inducible factor-2α (HIF-2α) and heart type-fatty acid-binding protein (H-FABP) of myocardial cells, in order to provide basis ...
FENG Guo-wei, LIU Xia, QI Qian, et al.
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Effect of ApoB/ApoA1 ratio on the all-cause mortality of patients with pulmonary embolism [PDF]
Objective To investigate the effect of ApoB/ApoA1 ratio on the all-cause mortality of patients with pulmonary embolism at admission. Methods One hundred and seventy-seven patients with hemodynamically stable pulmonary embolism were retrospectively ...
Ouyang Xiaoli, Zhao Huijun, Chen Juping
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Evaluation of Cardiac Structure and Function in Patients with Wilson Disease Based on RT-3DE: a Clinical Study [PDF]
Background Wilson disease (WD) is a rare autosomal recessive disease that causes impaired copper excretion, mainly manifestedashepatic and/or neuropsychiatric symptoms, but diversifies with the varying affected organs and severity of the disease.
ZHANG Yu, WANG Meixia, ZHANG Jing, WANG Fei, LI Zhonglei, ZHANG Yanyun, JIANG Zhenzhen
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热性惊厥合并感染患儿血清hs-CRP、hs-cTnI、CK-MB与心肌损伤的关系
目的 研究热性惊厥(FC)合并感染患儿血清超敏C反应蛋白(hs-CRP)、超敏心肌肌钙蛋白I(hs-cTnI)、肌酸激酶同工酶(CK-MB)与心肌损伤的关系。方法 选择广安市人民医院2018年3月-2021年6月诊治的95例FC合并感染患儿,其中FC合并感染患儿61例(对照组),并发心肌损伤组患儿34例(研究组)。检测其血清hs-CRP、hscTnI、CK-MB水平,分析hs-CRP与hs-cTnI、CK-MB水平相关性,并采用Logistic回归分析影响患儿并发心肌损伤的危险因素 ...
李小容 +3 more
doaj
A study of the effect of suboptimal glycemic control on subclinical myocardial systolic function in patients with T2DM [PDF]
Objective·To explore the relationship between poor blood glucose control and early impaired cardiac function in patients with type 2 diabetes mellitus (T2DM).Methods·Eighty-three patients diagnosed with T2DM in Jiading Branch of Shanghai General Hospital
CAO Mengmeng +7 more
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Prediction value of serum TMAO on myocardial injury after PCI in patients with coronary heart disease based on decision curve analysis [PDF]
Objective To explope the predictive efficacy of serum trimethylamine N ⁃ oxide(TMAO)on myocardial injury after percutaneous coronary intervention(PCI)in patients with coronary heart disease. Methods A total of 200 patients with coronary heart disease who
CHEN Guixiu,GUO Cheng,HE Lin
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The effect and mechanism of IL-1 R II / IL-1 RAcp in Autoimmune Myocarditis [PDF]
【目的】白介素-1(IL-1)是一种T淋巴细胞激活因子,大量研究报道,在心肌炎急性期表达量明显升高。白介素1受体II型(IL-1RII)可以招募白介素1受体辅助蛋白(IL-1RAcp),从而拮抗IL-1β的作用。本课题目的为评估IL-1RII和IL-1RAcp的重组质粒对大鼠自身免疫性心肌炎(EAM)的作用,并进一步探讨其机制,为心肌炎的临床治疗提供理论基础。 【方法】首先在临床实验中,我们选取厦门市心血管病医院诊断明确的心肌炎住院患者28例,应用bio ...
宋颖
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Study on the effect of myocardial injury induced by electrical injury in mice based on metabolomics [PDF]
Objective To study myocardial injury induced by electrical injury in mice based on metabolomics, and to find out the differential metabolites and pathways in cardiac metabolism omics.
CHEN Siyu +9 more
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The Role and Mechaninsm study of IL-20-related Cytokines contribute to Autoimmune Myocarditis in Mice [PDF]
目的:免疫相关因素与心肌炎引起的心肌纤维化密切相关。前期研究表明,IL-10家族成员在心肌炎慢性期心肌纤维化的形成过程中发挥重要作用。IL-20是最新发现的IL-10家族成员之一,具有调节细胞增殖和分化的作用。但IL-20是否参与心肌炎心肌纤维化过程尚不清楚。本课题通过实验探讨IL-20及其相关因子对小鼠自身免疫性心肌炎(EAM)心肌纤维化的影响及可能的分子调节机制。 方法:利用小鼠心肌肌球蛋白多肽MyHC6l4-629和完全弗氏佐剂充分混合后,于第0天和第7天皮下注射建立小鼠EAM模型;组织切片H ...
许俊铭
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