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基于肝脏转录组测序对不同海拔喜马拉雅旱獭的低氧适应性研究

open access: yes野生动物学报
为探究低、中、高3个不同海拔梯度下喜马拉雅旱獭(Marmota himalayana)基因表达是否存在差异,筛选该物种与高原低氧及强紫外辐射环境适应的相关候选基因,采用Illumina HiSeq 2500高通量测序平台对喜马拉雅旱獭肝脏组织进行无参转录组学分析,通过对质控后测序数据与参考基因组的比较分析,筛选差异表达基因后进行GO功能注释和KEGG富集分析。结果显示:乐都样品(低海拔组,LD)、玉树样品(高海拔组,YS)喜马拉雅旱獭肝脏组织中差异表达基因差异较大,刚察样品(中海拔组,GC ...
赵坤钰, 李优, 南新营, 李耀东
doaj  

[<i>Qingre Lidan Jiedu</i> Recipe improves high copper load-induced cognitive dysfunction in rats by regulating mitophagy]. [PDF]

open access: yesNan Fang Yi Ke Da Xue Xue Bao
Wang Y   +6 more
europepmc   +1 more source

[A spatial cognition model based on the selection mechanism of hippocampus place cells]. [PDF]

open access: yesSheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2020
Yu N, Liao Y, Zheng X.
europepmc   +1 more source

[Helicid alleviates depression-like behavior in rats with chronic unpredictable mild stress through the NCALD/sGC/cGMP/PKG axis]. [PDF]

open access: yesNan Fang Yi Ke Da Xue Xue Bao
DU X   +8 more
europepmc   +1 more source

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