Results 11 to 20 of about 64,307 (156)
低强度聚焦超声触发PLGA阿霉素在细胞内空化增加乳腺癌细胞死亡 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2021 目的探讨低强度聚焦超声能否触发聚乳酸-羟基乙酸共聚物（PLGA）包裹阿霉素在细胞内的空化作用以增加4T1肿瘤细胞的死亡。方法采用双乳化溶剂蒸发法制备了负载阿霉素的聚乳酸-羟基乙酸共聚物（PLGA）纳米气泡。设立细胞内释药组，细胞外释药组，传统给药组，单独超声组和对照组。用流式细胞仪检测各组细胞的死亡情况，用细胞活力检测试剂盒（CCK8）检测各组的细胞增殖，细胞划痕检测各组的侵袭情况。结果超声组细胞核的红色荧光平均强度高于对照组，差异具有统计学意义（t=16.627，P<0.001）；聚乳酸 ...
黄盘辉, 罗琼, 严飞, 李绍林
doaj +1 more source
World Medical &Health Policy, Volume 15, Issue 4, Page 414-434, December 2023., 2023 Abstract Cardiovascular disease (CVD) is the leading cause of death among American Indians and Alaska Natives (AIANs). Despite copious research on CVD incidence and outcome discrepancies, a social determinants of health (SDOH) focused framework on CVD risk factors and health outcomes in AIAN populations has not been undertaken.
Eric Leung +3 more
wiley +1 more source
World Medical &Health Policy, Volume 15, Issue 4, Page 587-612, December 2023., 2023 Abstract Drug overdose claimed more than 100,000 lives in the United States in 2021. Drug‐induced homicide (DIH) laws create specific criminal liability for individuals who provide drugs that cause or contribute to the death of another person. DIH prosecutions in the United States have increased substantially over the past decade despite the absence of
Jennifer J. Carroll +8 more
wiley +1 more source
The global challenge of cancer governance
World Medical &Health Policy, Volume 15, Issue 4, Page 672-681, December 2023., 2023 Abstract The global cancer statistics are stark, accounting for nearly 10 million deaths in 2020, around one in six of all deaths globally. The World Health Organization estimates that 70% of these cancer deaths occur in low‐ and middle‐income countries and cancer will continue to rise as a proportion of deaths in these settings.
Neil Lunt
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Conservation Biology, Volume 37, Issue 1, February 2023., 2023 Abstract Invasive species can dramatically alter ecosystems, but eradication is difficult, and suppression is expensive once they are established. Uncertainties in the potential for expansion and impacts by an invader can lead to delayed and inadequate suppression, allowing for establishment.
Brian D. Healy +5 more
wiley +1 more source
Journal of Traumatic Stress, Volume 35, Issue 5, Page 1460-1471, October 2022., 2022 Abstract This study examined posttraumatic stress disorder (PTSD), complex PTSD, depression, and anxiety among U.K. rail workers. A cross‐sectional survey examining exposure to seven psychosocial hazards (bullying/harassment; verbal abuse; physical and sexual assault; and hearing about, seeing the aftermath of, or witnessing a fatality), working ...
Laurence A. Carnall +3 more
wiley +1 more source
, 2022 本研究将以中国东北某省会城市的45~59周岁中年人群体为被试，探究成人依恋中的依恋回避和依恋焦虑两个维度与死亡焦虑之间的关系，其中假设人格特质在二者的关系中起中介作用 ...
杨东明
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PANoptosis 的分子作用机制及其在致盲性眼病中的作用
Zhongshan Daxue xuebao. Yixue kexue ban, 2023 以往研究认为各种细胞死亡途径有其独特的调控机制，近年来随着对细胞死亡途径的进一步研究发现各种途径之间存在串扰和协调，进而有研究提出一种新的细胞死亡途径：PANoptosis，认为PANoptosis是由PANoptosome复合物调节的炎症性程序性细胞死亡途径，具有细胞焦亡、细胞凋亡和/或坏死性凋亡的关键特征，并不能被细胞焦亡、细胞凋亡、坏死性凋亡中任意一种死亡方式单独表征。特定的触发因素如病毒、细菌及真菌感染可以诱导宿主以PANoptosis的途径死亡。本文就PANoptosis的相关通路 ...
李青青, 刘莲
doaj
, 2016 目的探索老年人自我报告的健康水平对幸福感的影响,并进一步探讨死亡焦虑在健康状况和幸福感之间的中介作用。方法采用一般健康量表、死亡焦虑量表及幸福感量表对随机抽样的老年样本进行调查。结果老年人幸福感总体上偏低,但是死亡焦虑水平偏高。老年人的健康水平对幸福感具有显著的预测作用(β=-0.38 ...
周明洁, 赵娜, 张建新, 张镇
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死亡意识对亲社会行为的影响：生命意义感的中介作用和特质焦虑的调节作用
, 2023 死亡意识是个体对自身死亡必然性的认识，具有前瞻性的死亡意识作为人类特有的认知能力和个体生命史的终极坐标, 不仅可能引起恐惧感和防御反应, 更重要的是可以促使人做出亲社会行为这一内在成长反应。为探讨死亡意识对亲社会行为的影响及其作用机制，本研究基于恐惧管理理论和创生理论构建了一个有调节的中介模型，重点考察生命意义感的中介作用及特质焦虑的调节作用。以大学生为被试，采用死亡凸显和死亡反省范式、生命意义感量表、特质焦虑量表和亲社会行为测量题项进行调查。本研究有助于人们在深刻认识“死”的基础上定义“生”的意义 ...
SHIQI CHENG
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