Mechanisms of Acquired Resisitance to EGFR Tyrosine Kinase Inhibitors in Non-small Cell Lung Cancer [PDF]
, 2009 Hongjie LI, Xiaoping LI
core
[A Case of Refractory Pulmonary Enteric Adenocarcinoma with EGFR Sensitive Mutation]. [PDF]
Zhongguo Fei Ai Za ZhiWang X +7 more
europepmc +1 more source
中国南方汉族群体27个Y-STR基因座的遗传多态性及 突变研究
Zhongshan Daxue xuebao. Yixue kexue ban, 2015 摘 要: 【目的】 调查27个Y-STR基因座在中国南方汉族群体的遗传多态性及突变情况?【方法】 采集885名中国南方汉族无关男性个体血样和911对父子血样,采用Yfiler?誖Plus扩增体系对样本进行扩增,并进行毛细管电泳检测与分型,统计相关遗传多态性参数,观察Y-STR基因座突变情况? 【结果】 885名无关男性个体中共观察到880种单倍型,其中875种单倍型为唯一单倍型,5种单倍型分别出现两次?单倍型多样性(HD)为0.999 987 2,系统识别能力(DC)为0.994 350 3?27个Y ...
doaj
Zhongshan Daxue xuebao. Yixue kexue ban, 2011 【目的】 探讨膜反向斑点杂交法在广东人G6PD基因6种常见突变同步检测中的应用【方法】 用高铁血红蛋白还原试验和G6PD/6-PGD酶活性比值法进行G6PD缺乏症筛查应用多重PCR方法扩增G6PD基因目的片段用Premier Primer6.0软件设计和优化针对广东人常见6种G6PD基因突变型的特异性寡核甘酸探针,用乙基-3-二甲氨基丙碳二亚胺(EDC)法处理尼龙膜并固定探针,制成G6PD基因突变检测用膜条多重PCR扩增产物与固定在膜条上寡核苷酸探针进行杂交 ...
doaj
[Pathogenic mechanisms of Leber hereditary optic neuropathy caused by m.3472T>C mutation]. [PDF]
Zhejiang Da Xue Xue Bao Yi Xue BanZhang H, Shan W, Yasheng M, Guan M.
europepmc +1 more source
[Clinical and molecular characteristics of myeloproliferative neoplasms patients with NFE2 gene mutations]. [PDF]
Zhonghua Xue Ye Xue Za ZhiZhao SY +15 more
europepmc +1 more source
A Case Report of Erlotinib as First-line Therapy in Extensive Metastatic Patient with Advanced Non-small Cell Lung Cancer [PDF]
, 2009 Wanfeng GUO, Xiaoqing LIU
core
[<i>PIK3CA</i> Somatic Mutations Are Associated With Lymph Node Metastasis in Endometrial Cancer]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanShen Q +5 more
europepmc +1 more source
[The clinical study of azacitidine and lenalidomide combination in myelodysplastic neoplasm patients with TP53 mutations]. [PDF]
Zhonghua Xue Ye Xue Za ZhiYan X +8 more
europepmc +1 more source
[Advances in Targeted Therapy for Advanced Non-small Cell Lung Cancer with HER2 Mutation]. [PDF]
Zhongguo Fei Ai Za ZhiYu J, Cao B.
europepmc +1 more source