Results 11 to 20 of about 5,918 (167)
Highlights Lipid profiles of small extracellular vesicles (sEVs) in patients with diabetes or diabetic cardiovascular disease are rarely reported. n‐3 docosahexaenoic acid (DHA)‐enriched triacylglycerol (TG) was found to decrease in sEVs from serum of patients with diabetic cardiovascular disease (DM‐CAD).
Wei Ding +3 more
wiley +1 more source
Highlights Childhood obesity was significantly associated with the increased risk of insulin resistance (IR). There were 12 metabolites co‐associated with childhood obesity and IR, including seven amino acid and five fatty acid metabolites. The combination of body mass index standard deviation score and key metabolites could effectively predict the ...
Wu Yan +5 more
wiley +1 more source
Highlights Among 301 studies, diabetes mellitus was the most studied cardiometabolic risk factor. In the network meta‐analysis, cerebrovascular disease had the highest impact (relative risk [RR] 1.69; 95% CI, 1.65–1.73) on COVID‐19 outcomes compared to other cardiometabolic risk factors.
Alina Binbin Li +9 more
wiley +1 more source
Highlights We used data from the genome‐wide association studies database and two‐sample mendelian randomization method, we found that genetic evidence supporting that knee osteoarthritis is a potential risk factor for type 2 diabetes. Abstract Background Physical inactivity is an independent risk factor for type 2 diabetes (T2D).
Xing Xing +3 more
wiley +1 more source
Highlights Mild acquired impaired thyroid hormone sensitivity was widespread among the general populations. Reduced thyroid hormone sensitivity was related with metabolic syndrome and its components. Impaired thyroid hormone sensitivity might affect the distribution of adipose tissue and muscle.
Fang Lv +6 more
wiley +1 more source
Highlights Type 2 diabetes mellitus (T2DM) is characterized by progressive loss of beta‐cell function and mass. Numerous mechanisms of beta‐cell failure are involved. Preservation and/or enhancement of beta‐cell function is of great importance in delaying the progression of T2DM and the burden of its complications. Accurate evaluation of the effects of
Laure Sayyed Kassem +3 more
wiley +1 more source
Highlights Increased glutamate is associated with the development of diabetes. Glutamate increases plasminogen (PLG) levels through glutamate metabotropic receptor 5 activation with various insulin resistance‐related stresses. Glutamate inhibits the conversion of PLG to plasmin by increasing plasminogen activator inhibitor‐1.
Hyo Jung Lee +7 more
wiley +1 more source
Highlights Laparoscopic sleeve gastrectomy and laparoscopic Roux‐en‐Y gastric bypass are effective for reducing weight and improving metabolic parameters in Chinese patients with obesity. These interventions resulted in improved glycemic control, as evidenced by decreased glycated hemoglobin levels, reduced insulin resistance, and improved ...
Wenhuan Feng +6 more
wiley +1 more source
Mechanisms of bariatric surgery for weight loss and diabetes remission 减重手术减轻体重和缓解糖尿病的机制
Highlights Controversial changes in intestinal hormones after bariatric surgery (BS) were summarized. The changes of signaling proteins involved in insulin resistance and the newly proposed changes in growth differentiation factor 15, exosomes, and extracellular vesicles after BS were elucidated.
Mengsha Yin +6 more
wiley +1 more source
Highlights In Chinese postmenopausal women with type 2 diabetes mellitus, serum follicle‐stimulating hormone levels were negatively and independently associated with the prevalence of nonalcoholic fatty liver disease. Metabolic conditions, including overweight/obesity, central obesity, hyperuricemia, hypertension, and dyslipidemia did not interact with
Shengjie Ge +10 more
wiley +1 more source

