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[Characteristics of Inflammatory Markers in Diabetic Foot Patients and Their Relationship With Prognosis of Diabetic Foot Ulcers]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban, 2023
目的 探究糖尿病足患者基线炎症标志物特征及其与足溃疡预后的关系。 方法 通过医院电子病历系统收集2016年以来在四川大学华西医院住院的495例糖尿病足患者的临床资料，分析炎症标志物特征及与足溃疡预后的关系。 结果 Wagner 4级患者白细胞计数（white blood cell count, WBC）、红细胞沉降率（erythrocyte sedimentation rate, ESR）、C反应蛋白（C-reactive protein, CRP）、降钙素原（procalcitonin, PCT ...
Wu J, Raju B, Zha P, Gong H, Ren Y, Li Z, Chen L, Liu G, Chen D, Wang C, Ran X.   +10 more
europepmc   +2 more sources

积雪草酸通过调控TNF-α/Mfn2通路改善2型糖尿病β细胞胰岛素分泌功能

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2023
目的 研究积雪草酸改善2型糖尿病β细胞功能的作用及分子机制。 方法 利用高脂饲料和链脲佐菌素构建2型糖尿病小鼠模型，评估不同浓度积雪草酸对2型糖尿病小鼠血糖调节作用，筛选积雪草酸最佳治疗浓度。体外采用棕榈酸处理小鼠胰岛构建2型糖尿病胰岛模型。针对积雪草酸处理后体内、外胰岛模型，利用酶联免疫吸附试验检测胰岛β细胞葡萄糖刺激的胰岛素分泌（GSIS）功能、胰岛内肿瘤坏死因子（TNF）α、白介素（IL）6含量，紫外分光光度法检测胰岛内腺苷三磷酸（ATP）含量，蛋白质印迹法检测胰岛β细胞成熟标志蛋白尿皮质素 ...
Lu Li, Wei Wang, Qiang Xu, Mingzhu Huang
semanticscholar   +1 more source

尿常规检验与生化检验在糖尿病诊断中的应用

临床医学与护理, 2023
目的：分析尿常规检验与生化检验在糖尿病诊断中的应用价值。方法：选择2018年10月至2020年10月收治的疑似糖尿病患者90例，全部采用生化检验和尿常规检验，分析尿常规检验和生化检验诊断的特异度、灵敏度、诊断准确率。结果：尿常规检验疾病阳性检出率明显低于生化检验，差异有统计学意义（P＜0.05）；尿常规检验的灵敏度、准确度均略低于生化检验结果（P＜0.05），两重检验方法的特异度相比无统计学差异（P＞0.05）。经分析，糖尿病组中尿糖、尿酮体、隐血占比均高于非糖尿病组（P＜0.05 ...
友全 朱
semanticscholar   +1 more source

左卡尼汀联合前列地尔治疗糖尿病肾病的临床观察

亚洲临床医学杂志, 2020
目的： 研究糖尿病肾病采用左卡尼汀联合前列地尔治疗的效果。 方法： 研究时段是 2017.4-2019.3，研究对象我院接收的 66例糖尿病肾病患者，采纳随机数字表法分为观察组（左卡尼汀联合前列地尔）与对照组（前列地尔）各 33 例，比较两组观察指标、肾功能、临床疗效及不良反应。 结果： 两组治疗前 CysC 与 RBP 指标无统计学意义，P ＞ 0.05；治疗后与对照组比较，观察组 CysC 与 RBP 指标低；BUN、SCr 及 β 2-MG 指标低；有效率高且不良反应发生率低，P ＜ 0.05 ...
峰明 张
semanticscholar   +1 more source

中西医结合护理干预对糖尿病患者血糖控制效果的影响

实用医学研究, 2020
在进行护理干预之后，观察组当中的患者在生活方式及血糖控制方面和对照组相比明显比较好（P＜0.05），相应的满意程度、住院的具体时间及费用等都存在差异，具备统计学意义（P＜0.05）。结论：采用中西医结合的护理干预可以非常有效地对糖尿病患者的血糖进行控制，更好地促进了患者的康复。
珍珍 郑
semanticscholar   +1 more source

Combined detection of urinary biomarkers noninvasively predicts extent of renal injury in patients with early diabetic kidney disease with kidney qi deficiency syndrome: A retrospective investigation

The Anatomical Record, Volume 306, Issue 12, Page 2945-2957, December 2023., 2023
Abstract Incipient diagnosis and noninvasive forecasts using urinary biomarkers are important for preventing diabetic kidney disease (DKD) progression, but they are also controversial. Previous studies have shown a potential relationship between urinary tubular biomarkers (UTBs) and traditional Chinese medicine (TCM) syndrome in patients with DKD. Thus,
Wei Wu, Xian‐Jie Meng, Bing‐Ying Wan, Qi‐Jun Fang, Ying‐Lu Liu, Jie Wang, Yan Fu, Can‐Can Yuan, Mei‐Zi Wang, Fee‐Lan Chong, Yi‐Gang Wan, Shan‐Mei Shen   +11 more
wiley   +1 more source

Rationale and design for the Blood Pressure Control Target in Diabetes (BPROAD) study 糖尿病血压控制目标(BPROAD)研究的原理和设计

Journal of Diabetes, Volume 15, Issue 12, Page 1029-1040, December 2023., 2023
Highlights The Blood Pressure Control Target in Diabetes (BPROAD) study is a multicenter, randomized controlled trial conducted in mainland China to test the hypothesis of whether intensive blood pressure (BP) management (systolic BP <120 mm Hg) has additional benefits over standard BP management (systolic BP <140 mm Hg) over a follow‐up period of up ...
The BPROAD Study Group, Guang Ning, Jiang He, Weiqing Wang, Yufang Bi, Dalong Zhu, Jiguang Wang, Shengdi Chen, Yu Xu, BPROAD coordinating team at Ruijin Hospital, Lawrence J. Appel, William C. Cushman, Vivian A. Fonseca, Jeff D. Williamson, David M. Reboussin, Yaling Han, Hongbing Shen, Minghui Zhao, Hui Wang   +18 more
wiley   +1 more source

Blood pressure targets for prevention of cognitive decline in patients with diabetes and hypertension: Design of the Blood Pressure Control Target in Diabetes (BPROAD) Cognitive Study 高血压目标对于预防糖尿病和高血压患者的认知下降:BPROAD认知研究的设计

Journal of Diabetes, Volume 15, Issue 12, Page 1041-1047, December 2023., 2023
Highlights The optimal blood pressure (BP) target in patients with type 2 diabetes mellitus (T2DM) for the management of cognitive decline remains unknown. The Blood Pressure Control Target in Diabetes (BPROAD) Cognitive Study was designed to determine whether intensive BP treatment (systolic BP <120 mm Hg) reduces risk of dementia and mild cognitive ...
The BPROAD Study Group, Guang Ning, Jiang He, Weiqing Wang, Yufang Bi, Dalong Zhu, Jiguang Wang, Shengdi Chen, Yu Xu, BPROAD coordinating team at Ruijin Hospital, Lawrence J. Appel, William C. Cushman, Vivian A. Fonseca, Jeff D. Williamson, David M. Reboussin, Yaling Han, Hongbing Shen, Minghui Zhao, Hui Wang   +18 more
wiley   +1 more source

Patient experiences of continuous glucose monitoring and sensor‐augmented insulin pump therapy for diabetes: A systematic review of qualitative studies 糖尿病患者接受连续血糖监测和传感器增强胰岛素泵治疗的体验:对定性研究的系统综述

Journal of Diabetes, Volume 15, Issue 12, Page 1048-1069, December 2023., 2023
Highlights We identified that CGM can increase motivation for self‐management and confidence in treatments. A supportive treating team may help to reduce the practical and psychological burden in patients with type 1 and type 2 diabetes. Abstract Aims Blood glucose control is central to the management of diabetes, and continuous glucose monitoring (CGM)
Patrizia Natale, Sharon Chen, Clara K. Chow, Ngai Wah Cheung, David Martinez‐Martin, Corinne Caillaud, Nicole Scholes‐Robertson, Ayano Kelly, Jonathan C. Craig, Giovanni Strippoli, Allison Jaure   +10 more
wiley   +1 more source

Early weight gain after diagnosis may have an impact on remission status in children with new‐onset type 1 diabetes mellitus 儿童新发1型糖尿病诊断后早期体重增加可能对缓解状态产生影响

Journal of Diabetes, Volume 15, Issue 12, Page 1011-1019, December 2023., 2023
Highlights Weight gain with insulin therapy in the early period may be negatively related to the occurrence and duration of remission by altering insulin sensitivity. Interventions to prevent rapid weight gain and conserve insulin sensitivity in the early stages of type 1 diabetes mellitus may be beneficial for the development and maintenance of ...
Dicle Canoruc Emet, Hande Nur Karavar, Onur Gozmen, Arife Aslan Agyar, Yağmur Ünsal, Merve Canturk, Pınar Cengiz, Dogus Vuralli, Z. Alev Ozon, E. Nazlı Gonc   +9 more
wiley   +1 more source