Results 21 to 30 of about 149,866 (255)

思春期に発症した非肥満型2型糖尿病とともに生きる患者の経験 [PDF]

open access: yes, 2019
食生活の欧米化等に伴い、小児・思春期発症2型糖尿病の増加がみられる。しかし、小児・思春期発症2型糖尿病の患者がどのような経験をしながら成長しているのか明らかにされていない。そこで,本研究は,思春期に発症した非肥満型2型糖尿病とともに生きる患者の成長過程における経験を明らかにし,継続的な支援の示唆を得ることを目的とした。半構造化インタビューにより得られた語りを、テーマ的ナラティブ分析を用いて分析した。その結果,患者の語りから、【糖尿病を受けとめられない思春期】、【糖尿病の受けとめが変化する青年期 ...
沖本 克子, 網野 裕子
core   +1 more source

Evolving trends of antidiabetic agents stratified by age, kidney function and body mass index: Insights from a nationwide claims database

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 701-710, January 2026.
Abstract Aims To analyse prescribing trends in antidiabetic agents stratified by background characteristics among individuals with type 2 diabetes. Materials and Methods This retrospective study used a large‐scale database between 2015 and 2024 in Japan.
Kazuki Aoyama   +14 more
wiley   +1 more source

Reprint:Prediction of Retinapathy Using HbA1C Data in Type 1 Diabetes [PDF]

open access: yes, 2017
「1 型糖尿病の治療&ケアエッセンス(仮)」東京女子医大糖尿病センター編(2017)より転載内科学(第三)講座 講座主任 ...
廣瀬 晶
core   +1 more source

Hypoglycemic activity of Momordica charantia (bitter melon) [PDF]

open access: yes, 2012
Diabetes mellitus (DM) represents a global health and economical problem. Many patients with DM in Asia, South America, India and East Africa have traditionally used the water extract of unripe fruits of Momordica charantia (bitter melon) as some form of
Mankura, Mitsumasa   +2 more
core   +1 more source

Increased HbA1c relative to actual glycemic control in patients treated with sodium–glucose cotransporter 2 inhibitors

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 1, Page 34-41, January 2026.
ABSTRACT Aims/Introduction Among patients with diabetes receiving sodium–glucose cotransporter 2 (SGLT2) inhibitors, HbA1c levels are higher than glycated albumin levels. This study therefore aimed to evaluate the discrepancy between HbA1c and glucose management indicator (GMI), an index of glucose management derived from continuous glucose monitoring,
Keigo Mizutani   +14 more
wiley   +1 more source

Structure and function research of the nuclear receptor PPARγ and its novel selective regulator [PDF]

open access: yes, 2016
过氧化物酶体增殖剂激活受体家族(PPARs)是一类配体依赖型的激活因子,它们是核受体超家族中的重要成员。PPARs是机体调节新陈代谢平衡的关键转录因子,因此PPARs也成为了研发治疗糖尿病,心血管疾病等代谢相关疾病药物的热门分子靶标。 糖尿病是困扰现代人健康的一组常见代谢性疾病,但是目前临床上仍然缺乏安全且有效的糖尿病治疗药物。噻唑烷二酮(Thiazolidinedione,TZD)类药物是经典的PPARγ完全激动剂,由于它能够改善由糖尿病引起的胰岛素耐受等症状,目前已经运用于临床治疗Ⅱ型糖尿病 ...
邱琳
core  

Social stigma of diabetes in Taiwan: An analysis of public perceptions and disease name unpleasantness

open access: yesJournal of Diabetes Investigation, Volume 16, Issue 12, Page 2242-2249, December 2025.
ABSTRACT Aims Social stigma related to diabetes affects self‐care and psychological well‐being. In Taiwan, negative perceptions of “diabetes mellitus” may contribute to this stigma. This study explores public attitudes toward people with diabetes and the unpleasantness linked to the disease name.
Der‐Yan Han   +6 more
wiley   +1 more source

成人迟发性自身免疫性糖尿病的研究进展

open access: yesZhongguo shiyan zhenduanxue, 2019
糖尿病是由多种原因引起的一类以慢性高血糖为特征的代谢性疾病,近年来,糖尿病的患病率在迅速上升,根据国际糖尿病联合会的糖尿病图谱,世界上大约有4亿人患有2型糖尿病,每年有1000万人被诊断患有糖尿病[1]。按现行的分类标准,糖尿病主要分为1型糖尿病(T1DM)、2型糖尿病(T2DM)、妊娠期糖尿病等特殊类型糖尿病。有些T1DM患者发生在成年期,即成人迟发性自身免疫性糖尿病(laten-
宁利俐   +4 more
doaj  

Danggui sini Decoction attenuated diabetic neuropathy in diabetic rats [PDF]

open access: yes, 2016
摘要 目的:糖尿病神经病变(Diabeticneuropathy,DN)是糖尿病常见的并发症之一。我们以往的研究发现当归四逆汤加减方(DangguisiniDecoction,DSD)能够缓解糖尿病神经病变引起的疼痛。本实验拟观察当归四逆汤加减方(DSD)对糖尿病大鼠坐骨神经和脊髓中一氧化氮(nitricoxide,NO)、一氧化氮合酶(Inducednitricoxidesynthase,NOS)、抗氧化酶、凋亡相关蛋白和硝基酪氨酸(nitrotyrosine,NT)蛋白和对后肢爪垫表皮内神经纤维影响。
陈宁宁
core  

L‐Theanine Suppresses the Increase in Blood Glucose Levels in Mice During Glucose Tolerance Tests by Promoting Glucose Excretion in the Urine

open access: yesFood Science &Nutrition, Volume 13, Issue 10, October 2025.
L‐theanine suppresses the increase in blood glucose levels occurring during an OGTT in mice by promoting glucose excretion in the urine. While further investigation is needed to clarify the underlying mechanism, our study findings suggest that L‐theanine has the function of suppressing a rise in blood glucose levels and has the potential to contribute ...
Shinnosuke Yamaura   +9 more
wiley   +1 more source

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