Results 31 to 40 of about 1,241,830 (150)
Zhongguo shiyan zhenduanxue, 2011 目的探讨呼吸道分离的金黄色葡萄球菌耐药情况、耐药的菌株是否有遗传稳定性,及对其他种类的抗生素有无交叉耐药。方法把试验菌株与标准菌株在不同含药平皿中接种传代,观察MIC值的变化,再测定遗传稳定性及有无交叉耐药。结果试验菌株与标准菌株多次传代后,耐药突变菌株获得的耐药性是稳定的。未对其他种抗生素发生交叉耐药。结论合理选用抗生素,监测细菌耐药性、掌握耐药机制等综合措施的实施,才能减缓细菌耐药性的增长。
王轶, 刘珊珊, 黄瑾
doaj
Veterinary Dermatology, Volume 36, Issue 6, Page 825-837, December 2025.Background: Inhibition of the Janus kinase pathway is an established treatment for allergic dermatitis. Objective: To evaluate the efficacy and safety of ilunocitinib for control of pruritus in dogs with allergic dermatitis in a randomised, double‐masked clinical trial.
Sophie Forster +5 more
wiley +1 more source
, 2013 目的了解医院感染多重耐药菌分布及耐药性分析,为临床诊疗提供依据。方法 25 618例临床感染标本分离株培养鉴定后,监测常见分离菌的多重耐药菌株(MdrO)。结果 1 087株分离菌以革兰阴性菌925株为主,革兰阳性菌162株。革兰阴性菌中分离率前5位分别是肺炎克雷伯菌、大肠埃希菌、铜绿假单胞菌、鲍曼不动杆菌、阴沟肠杆菌。革兰阳性菌中分离率前5位分别是金黄色葡萄球菌、凝固酶阴性葡萄球菌、肺炎链球菌、屎肠球菌、粪肠球菌。大肠埃希菌、肺炎克雷伯菌产超广谱β-内酰胺酶(ESblS)株的检出率分别为75.53 ...
郑燕红, 蔡海明, 胡霞辉
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Veterinary Dermatology, Volume 36, Issue 5, Page 621-629, October 2025.Background – Canine superficial bacterial folliculitis (SBF) is a common recurrent condition with a growing requirement for culture and susceptibility as a consequence of increased antimicrobial resistance and antimicrobial stewardship. Different opinions persist about the ideal technique for culture sample acquisition, which varies with lesion ...
Jason B. Pieper +3 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2020 目的探讨中段尿培养阳性病原菌分布及耐药分析,为临床合理用药提供依据。方法收集2016年1月1日至2018年12月31日中段尿培养阳性病例,菌株鉴定与药敏试验采用迪尔DL-96Ⅱ细菌鉴定分析系统,结果判读依据美国临床实验室标准化研究所CLSI(2016年)标准。结果中段尿培养阳性标本主要来源于泌尿外科336株(48.98%);686株阳性病原菌中,革兰阴性菌620株(90.38%)、革兰阳性菌25株(3.64%)、侵袭性真菌41株(5.98%),居前4位的检出菌为:大肠埃希菌372株(54.23 ...
李芬, 杜希林, 李亮, 熊雪松
doaj
Veterinary Dermatology, Volume 36, Issue 5, Page 552-565, October 2025.Abstract Background Canine pyoderma is one of the most common presentations in small animal practice, frequently leading to antimicrobial prescribing. Objectives To provide clinicians with antimicrobial treatment guidelines for staphylococcal pyoderma, including those involving meticillin‐resistant staphylococci.
Anette Loeffler +9 more
wiley +1 more source
, 2007 【目的】探讨耐氟康唑白念珠菌基因多态性与其耐药性是否相关。【方法】收集48株敏感白念珠菌和10株耐氟康唑白念珠菌,其中包括2株体外诱导的耐氟康唑白念珠菌。选择1个随机引物(引物1251),采用任意引物PCR方法基因分型,将电泳图谱扫描入计算机后采用Labwork4.0软件转化为数值图表,利用SPSS11.5进行聚类分析。【结果】引物1251的PCR指纹图带型稳定,多态性丰富,可以作为分型引物。聚类分析结果提示8株临床耐药菌的PCR指纹图相似系数为71.7%,而其中7株的耐药菌相似系数高达86.7 ...
刘慧 +5 more
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Zhongguo shiyan zhenduanxue, 2012 随着广谱抗生素广泛应用于临床,细菌耐药性的发生、发展是当前感染领域的一大难题,一些细菌对药物的敏感性不断发生变化,造成临床经验用药失败,严重影响和阻碍了感染性疾病的控制和治疗。耐药菌株的增加,使得感染难以控制,大大增加了医疗费用的支出。因细菌的耐药性有其地域性,现对我院2010年一年临床分离病原菌排在前五位的细菌耐药性进行连续性监测和报告,以便及时了解我院细菌对临床应用的抗生素耐药性变化,根据病原菌药敏实验合理用药,对控制医院感染细菌耐药性发展至关重要。
张晓梅, 宋伶俐
doaj
Veterinary Dermatology, Volume 36, Issue 3, Page 302-313, June 2025.Background – Malassezia pachydermatis (MP) is implicated in severe dermatitis and otitis externa (OE) of companion animals and recently gained attention for its increasing resistance to azole compounds. For this reason, developing novel therapeutic strategies is of great interest. In a previous work, we used reference yeast isolates to evaluate several
Costanza Spadini +11 more
wiley +1 more source
, 1998 本论文包括以下几方面的研究内容：我国鱼类病原细菌的耐药性调查和分析：病原细菌对常用药物的抗性发展研究；药物的血液浓度与耐药性的关系；耐药质粒的检测；耐药质粒的生物学特性；耐药质粒的消除；质粒特征与耐药性的关系；海水、半咸水对抗菌药物抗菌作用的影响；环丙沙星和氯霉素的杀菌作用及抗生素后效应研究。具体结果如下：(1) 从不同地区分离收集到的35株鱼类病原菌(包括嗜水气单胞菌、迟缓爱德华氏菌、鲁氏耶尔森菌、弧菌、假单胞菌和未定种病原菌)中，对青霉素和半合成青霉素、头孢菌素及万古霉素耐药的菌株比例最高，为85 ...
李爱华
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