Results 11 to 20 of about 9,169 (174)

Modified rush venom immunotherapy in dogs with Hymenoptera hypersensitivity

open access: yesVeterinary Dermatology, Volume 34, Issue 6, Page 532-542, December 2023., 2023
Background – Hymenoptera envenomation occurs frequently in people and dogs and can trigger anaphylaxis. Venom immunotherapy (VIT) is the only preventative treatment for Hymenoptera hypersensitivity and is indicated for people with severe adverse reactions to insect stings. Rush VIT is an accelerated VIT induction schedule performed in people.
Alexandra Moore   +4 more
wiley   +1 more source

P1237: HSF1 PROMOTES CHEMORESISTANCE IN DIFFUSE LARGE B‐CELL LYMPHOMA VIA A PRMT5‐DEPENDENT TRANSCRIPTIONAL PROGRAM HSF1通过PRMT5依赖性转录程序促进弥漫性大B细胞淋巴瘤的化疗耐药性

open access: yes, 2023
HemaSphere, Volume 7, Issue S3, August 2023.
Qingqing Cai   +7 more
wiley   +1 more source

Bacteriophage and Fusidic Acid Have Synergistic Effect Against Meticillin‐Resistant Staphylococcus pseudintermedius in Ex Vivo Canine Dermis Model

open access: yesVeterinary Dermatology, Volume 37, Issue 2, Page 200-210, April 2026.
Background: Antimicrobial stewardship has become vital given the progressive emergence of multidrug‐resistant bacteria, and novel approaches to the treatment of bacterial infections are needed. Recently, reported synergistic effects of antibacterial drugs and bacteriophage therapy have revealed promising applications for the management of meticillin ...
Sarah Ehling   +9 more
wiley   +1 more source

Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan   +5 more
wiley   +1 more source

Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang   +9 more
wiley   +1 more source

Recent Progress in the Development of Metal‐Based Radiosensitizations for Cancer Therapy: A Review

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Radiotherapy (RT) remains an indispensable means in cancer treatment; however, its therapeutic efficacy is often limited by tumor radioresistance and side effect of damage to healthy tissue. The advances in nanotechnology have propelled metal radiosensitizers to forefront of precision medicine.
Xiao‐Xia Wu   +12 more
wiley   +1 more source

Multi‐Scale Rational Design and Synergistic Strategies of Nanozymes for Targeting Drug‐Resistant Pathogens

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT The escalating issue of drug‐resistant pathogens, largely driven by the overuse of conventional antibiotics, has become a significant global health threat. Developing alternative therapeutic strategies and fabricating natural biological enzyme materials that mimic the high efficiency, selectivity, and mild‐operating conditions of natural ...
Shuai He   +11 more
wiley   +1 more source

The new electrochemical DNA sensor for detection of Mycobacterium tuberculosis and its drug resistance gene [PDF]

open access: yes, 2016
耐药结核分枝杆菌,尤其是耐多药结核分枝杆菌的出现给结核病的检测和治疗带来了巨大的挑战,对人类健康产生了极大威胁。目前临床上常用的结核病的检测方法分别存在操作繁琐、仪器昂贵、耗时较长及易污染等不足。电化学DNA传感器是近几年发展起来的一种新型生物传感器,因其简单、灵敏、特异性强、易微型化等特点受到研究者的青睐,已被应用于多个领域的研究。然而电化学DNA传感器易受其他因素的干扰造成结果不稳定。实验前期构建的BSA单分子层控制组装界面为基础的电化学DNA传感器,有效地提高了体系的稳定性。本文在前期研究基础上 ...
李茜茜
core  

To Ban or Not to Ban: The UK's Hamlet Moment With Farm Antibiotics

open access: yesPolitics &Policy, Volume 53, Issue 6, December 2025.
ABSTRACT This article applies the Multiple Streams Framework (MSF) to examine post‐Brexit antimicrobial resistance (AMR) governance in UK agriculture, focusing on the contested regulation of prophylactic antibiotic use in farm animals. The study reveals how Brexit created a structural policy window, yet political and ideological dynamics rendered it ...
George Asiamah
wiley   +1 more source

Nanodrug delivery in reversing multidrug resistance in breast cancer cells [PDF]

open access: yes, 2016
乳腺癌细胞产生多药耐药(Multidrugresistance,MDR)是乳腺癌化疗失败最主要的原因之一,深入研究拮抗或逆转乳腺癌多药耐药有着重要的理论和临床意义。紫杉醇(Paclitaxel,PTX)是目前临床上广泛应用的广谱抗癌药物。临床广泛使用的紫杉醇制剂(商品名“泰素”)毒副反应严重,超敏反应强烈,无明显靶向性,可诱发多药耐药,因此紫杉醇新制剂研究是当前国际国内的热点问题。 本文旨在研制出具有良好临床适应性、可逆转肿瘤多药耐药的紫杉醇纳米制剂,并使其具有磁靶向和光动力治疗的多重功能。首先 ...
王颖君
core  

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