Roles of the Keap1/Nrf2 pathway and mitophagy in liver diseases. [PDF]
Zhou Q, Cen P, Chen Z, Jin J.
europepmc +1 more source
Role of PI3K/Akt/mTOR pathway-mediated macrophage autophagy in affecting the phenotype transformation of lung fibroblasts induced by silica dust exposure. [PDF]
DU Y, Huang F, Guan L, Zeng M.
europepmc +1 more source
[<i>Qingre Lidan Jiedu</i> Recipe improves high copper load-induced cognitive dysfunction in rats by regulating mitophagy]. [PDF]
Wang Y +6 more
europepmc +1 more source
[The miR-30b/USP14 axis regulates mitophagy via a non-PINK1/Parkin pathway in neuronal oxygen-glucose deprivation/reoxygenation injury]. [PDF]
Bei YH, Yu K, Wang X.
europepmc +1 more source
Fe3O4@PDA标记的脐带间充质干细胞对高糖环境下肾小管上皮细胞自噬的影响
目的分析Fe3O4@PDA标记的脐带间充质干细胞(hUCMSCs) 在高糖(HG)环境下对肾小管上皮细胞(HK2细胞)的影响,探讨其对HG环境下HK2细胞自噬的作用机制。方法合成Fe3O4@PDA纳米粒子(Fe3O4@PDA NPs),培养hUCMSCs、HK2细胞,将HK2细胞分为4组,包括①对照组②HG组③Fe3O4@PDA hUCMSCs组④hUCMSCs组。通过CCK8检测各组HK2细胞活力,Western blot检测各组HK2细胞中自噬相关蛋白Beclin1和p62的表达水平,RT ...
张金妹 +4 more
doaj
[Astragaloside IV alleviates D-GAL-induced endothelial cell senescence by promoting mitochondrial autophagy via inhibiting the PINK1/Parkin pathway]. [PDF]
Yi M +6 more
europepmc +1 more source
[The role and mechanism of autophagy in lipopolysaccharide-induced inflammatory response of A549 cells]. [PDF]
Shi J +8 more
europepmc +1 more source
3-methyladenine抑制自噬诱导胰腺癌细胞SW1990失巢凋亡
【目的】 探讨3-methyladenine(3-MA)对人胰腺癌SW1990细胞增殖?迁移及失巢凋亡的影响作用及其机制?【方法】 以胰腺癌细胞SW1990及永生化胰腺导管上皮细胞H6C7为研究对象,设3-MA处理组及PBS对照组,采用软琼脂克隆培养法及Poly-HEMA悬浮培养法筛选抵抗失巢凋亡的细胞?Annexin V-FITC/PI双染和TUNEL试剂盒法检测细胞凋亡;免疫荧光法及透射电镜检测细胞自噬;CCK-8法检测细胞增殖; Transwell小室检测细胞迁移能力?【结果 ...
doaj
Autophagy in skeletal muscle dysfunction of chronic obstructive pulmonary disease: implications, mechanisms, and perspectives. [PDF]
Han X +7 more
europepmc +1 more source
[Carnosine protects against diabetic nephropathy in rats by activating the AKT/mTOR pathway and restoring autophagy in the renal tissue]. [PDF]
Ren Y, Lu J, Yu L, Li Z, Wang G, Yang J.
europepmc +1 more source

