阻塞性睡眠呼吸暂停伴认知障碍患者中血清miR-132表达及意义 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2019 【目的】探讨miR-132在阻塞性睡眠呼吸暂停（OSA）伴认知障碍患者血清中的表达及其意义。【方法】根据蒙特利尔认知评估（MoCA）评分，将66名年龄在30~60岁之间的阻塞性睡眠呼吸暂停患者分为两组：认知障碍OSA组（OSAI组，n=36）、无认知障碍OSA组（OSAN组，n=30），30名无OSA的成年人作为对照组（HC组，n=30）。对其3组分别进行睡眠测试（OCST）和MoCA评估，并通过PCR检测血清中miR-132的相对表达量。【结果】HC组、OSAI组及OSAN组在年龄、教育程度 ...
王新立 +7 more
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Zhongguo cuzhong zazhi, 2023 血管性认知障碍是脑血管病变及其危险因素导致的认知功能下降，已逐渐成为当代社会的重大公共卫生问题。神经心理学和影像学表现是血管性认知障碍诊断和分型的“金标准”。本文将回顾神经心理学和影像学在血管性认知障碍精准诊断和进展预测等临床应用方面的研究进展，除了卒中后认知障碍和皮质下缺血性血管性认知障碍外，本文还关注了低灌注性认知障碍和混合型认知障碍的研究进展。 Abstract: Vascular cognitive impairment (VCI) is a decline in cognitive ...
程安琪，刘彩燕，徐蔚海
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卒中患者血压水平与卒中后认知障碍关系的研究进展 Progress of Blood Pressure and Post-stroke Cognitive Impairment
Zhongguo cuzhong zazhi, 2023 卒中后认知障碍为卒中的常见并发症之一，可严重影响卒中患者的生活质量及预后。目前认为血压与卒中后认知障碍密切相关，血压可能对卒中后认知障碍的主要病理生理过程产生潜在影响，并且控制血压可能有助于卒中后认知障碍的改善或预防。血压与卒中后认知障碍之间的相关性较为复杂，可能取决于特定的血压参数和卒中的不同阶段。目前卒中后的最佳血压控制水平尚不统一。本文对卒中后认知障碍的流行病学，血压与卒中后认知障碍的相关性，血压影响卒中后认知障碍的相关机制，以及控制血压的作用进行综述 ...
吴雅婷,魏宸铭,武剑
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Research Progress on the Relationship between Osteoporosis and Cognitive Impairment [PDF]
, 2022 In recent years, studies have shown that among elderly comorbidities, the incidence of comorbidity between osteoporosis and cognitive impairment is increasing year by year, which is manifested as a high incidence of falls and an increased risk of ...
REN Yun, TAO Liyuan, FAN Dongwei
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Causal relationship between atrial fibrillation and cognitive impairment: a Mendelian randomization study [PDF]
, 2023 Objective·To investigate the causal relationship between atrial fibrillation (AF) and cognitive impairment.Methods·A two-sample Mendelian randomization (TSMR) analysis was used to assess the potential causality of AF on cognitive dysfunction.
GAO Xiong +5 more
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Progression and Reversion of Mild Cognitive Impairment：a Study Using Data from the Uniform Data Set [PDF]
, 2022 BackgroundMild cognitive impairment (MCI) has highly variable cognitive trajectories. Approximately 10% to 15% of MCI patients progress to dementia, and nearly 24% revert to normal cognition each year.
HAN Hongjuan, QIN Yao, CHEN Durong, AN Jianhua, YU Hongmei
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Latest Research on the Neuroprotective Mechanism of Short-chain Fatty Acids in Stroke and Its Relation with Post-stroke Cognitive Impairment [PDF]
, 2022 Post-stroke cognitive impairment is one of the common complications of stroke, seriously affecting patients' ability to perform activities of daily living.
LIU Huanhuan, LI Ruiqing, SU Kaiqi, YUAN Jie, LI Qi, FENG Xiaodong
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Zhongguo cuzhong zazhi, 2022 卒中后认知障碍是卒中的重要后遗症之一，从病理上可以分为血管性、退变性及混合性认知障碍。水通道蛋白4广泛分布于中枢神经系统，参与多种神经系统疾病和认知障碍的病理过程，但其参与卒中后认知障碍的具体机制目前尚未明确。本文综述水通道蛋白4通过参与调节神经炎症、突触可塑性以及β-淀粉样蛋白的积聚和清除过程在卒中后认知障碍中发挥的可能作用。 Abstract: Post-stroke cognitive impairment is one of the main sequelae of stroke ...
梁潇，钱海兵
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Quality Assessment of Guidelines forVascular Cognitive Impairment Using the AGREEⅡ [PDF]
, 2022 BackgroundAs the second primary type of cognitive impairment worldwide, vascular cognitive impairment (VCI) is closely associated with cerebrovascular risks, which imposes a heavy burden on the society and families.
MA Huaping, HAN Zhenyun, CHANG Ze, WANG Yuchun, HU Yuli, ZHANG Dingding
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Research progress in the effect of nutritional intervention on cognitive impairment related to Alzheimer's disease [PDF]
, 2023 Alzheimer's disease (AD) is an age-related neurodegenerative disease with insidious onset and slow progression. The progression of AD from only brain pathological changes to clinically identifiable cognitive changes is affected by a variety of ...
HUANG Gaozhong, JIANG Xinting
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