Results 21 to 30 of about 11,374 (168)

Tolerability and Feasibility of Minimally Invasive Canine Skin Sampling: Excellent Tolerability Meets Transcriptomic Challenges

open access: yesVeterinary Dermatology, EarlyView.
ABSTRACT Background Advances in transcriptomics have driven the demand for minimally invasive, reproducible and high‐yield skin sampling methods, particularly for studying inflammatory skin diseases in companion animals. Hypothesis/Objectives We tested tolerability, feasibility and RNA quantity and quality of three minimally invasive skin sampling ...
Ina Herrmann   +2 more
wiley   +1 more source

Separation and Activity Screening of Peptides Derived from Mycale phyllophila [PDF]

open access: yes, 2015
海绵是最原始的多细胞生物,拥有许多在结构上非常多样化的生物活性物质,是最具有药物开发潜力的海洋生物资源。这些生理活性物质常具有抗肿瘤、抗病毒、抗细菌、抗真菌、杀虫、抗炎、神经抑制、神经保护、防污等作用。作为海绵活性物质中重要的组成部分,海绵活性多肽具有分子量小、结构简单、生物效应多样、免疫原性低等特点,具良好的开发潜力。叶片山海绵(Mycalephyllophila)是福建沿海资源较丰富的物种,本研究以叶片山海绵为材料,建立海绵水溶性肽类的分离纯化、活性筛选和结构测定的方法 ...
贺腾飞
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Developing HMME‐Conjugated NIR‐II Activated Carbon Dots Nanospray for the Treatment of MRSA Biofilm Infections in Diabetic Wound via PTT/CDT/SDT

open access: yesRare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT Diabetic wound infections are a common complication of diabetes, which severely impact patients' quality of life. Effective treatment of diabetic wound infections remains one major challenge in the clinic, partially due to the formation of bacterial biofilm and antibiotic resistance.
Liang Zhou   +8 more
wiley   +1 more source

Transcriptomic study of a toxin-producing dinoflagellate Alexandrium catenella [PDF]

open access: yes, 2015
亚历山大藻(Alexandriumspp.)是一种能够产生麻痹性贝类毒素(paralyticshellfishtoxins,PSTs)的海洋甲藻,广泛分布于近海环境中。近年来由其产生的毒素导致的海洋生物死亡及人类中毒事件频发,严重威胁到近海生态系统、水产养殖业、人类健康和生命财产安全,已成为一个全球性的环境和健康问题。虽然目前在亚历山大藻毒素来源及产毒生理方面取得了较大进展,但对毒素合成机制的了解仍较少。 本论文以有毒链状亚历山大藻(Alexandriumcatenella)为研究对象 ...
张勇
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Bridging the Digital Divide: Examining the Role of Digital Health in Nepal's Healthcare Transformation

open access: yesWorld Medical &Health Policy, Volume 18, Issue 1, March 2026.
ABSTRACT This systematic review examines the digital health interventions for inclusive and equitable solutions for transforming healthcare access and delivery in Nepal. The research focuses on improving digital health accessibility among marginalized and rural populations of Nepal.
Manoj Kumar Dahal, Gary L. Kreps
wiley   +1 more source

Studies on Heat Tolerance in Abalone Based on the Measurement of Heart Rate [PDF]

open access: yes, 2016
鲍是海产八珍之首,2015年,我国的鲍产量已经超过13万吨,其中福建省的产量占全国的80%。皱纹盘鲍为温带种,原分布于我国黄、勃海海域,1990年代后期南移福建后,获得了极大发展,由此福建逐步成为我国鲍养殖的主产区。但福建海域的夏季高水温往往导致鲍的高死亡率,这一直困扰着鲍养殖产业的发展。因此,培育耐高温的养殖新品种显得格外重要,而其中建立鲍的耐高温性状的准确测评方法是品种培育的关键。本研究中,我们通过测定阿氏拐点温度(Arrheniusbreakpointtemperature,ABT ...
陈楠
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SWEET1‐mediated glucose transport is crucial for energy availability in Arabidopsis

open access: yesNew Phytologist, Volume 249, Issue 4, Page 1816-1830, February 2026.
Summary The stress‐responsive hormone abscisic acid (ABA) is known for its inhibitory effects on various physiological processes, including seed germination, often resulting in energy deprivation. Interestingly, ABA‐induced germination inhibition can be alleviated by exogenous glucose (Glc), mimicking a functional interplay between ABA and sugar ...
Xueyi Xue   +3 more
wiley   +1 more source

Gene structure analysis and differentially splicing between Plasmodium yoelii subspecies [PDF]

open access: yes, 2016
啮齿类动物约氏疟原虫(Plasmodiumyoelii)是研究宿主-寄生虫相互关系和疟原虫病理分子基础的一种重要的动物模型。尽管约氏疟原虫YM虫株的基本基因组信息已被测定,在最近也有许多啮齿类动物疟原虫的RNA-seq序列信息已见报道,但不同疟原虫品系或者亚种之间可能存在基因编码区及mRNA转录结构上的差异。构建多种疟原虫品系和亚种的cDNA文库将有助于我们对疟原虫遗传模式和转录组结构的认识。 本研究,我们用约氏疟原虫NSM虫株有或无MQ药物压力的红内期原虫样本构建了两个cDNA文库并对其进行深度测序 ...
刘建文
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CHINA’S LAND FINANCE AS ACTIVE MODE OF LAND DEVELOPMENT AND INFRASTRUCTURE DELIVERY: Reality, History and Prospects

open access: yesInternational Journal of Urban and Regional Research, Volume 50, Issue 1, Page 191-220, January 2026.
Abstract Henry George advocated for capturing land value increases for public ends. The active approach of public authorities organizing and financing land development can help capture higher land value increases, as Hartman and Spit indicate. However, this approach hardly happens in developing countries, where the coalition of private developers and ...
Nannan Xu
wiley   +1 more source

The Study of Ultrastructure、ATP、Calcium and RNA-Seq in fertile and sterile anthers of Lycium Barbarum L. [PDF]

open access: yes, 2016
高等植物的雄性不育是杂种优势利用的基础,避免了去雄的繁杂程序。植物雄性不育的种类很多,形成原因也很复杂,对雄性不育机理的探索一直是一个热门研究领域。枸杞雄性不育系是近年来新发现的一种不育类型,具有很大应用潜力,为了明确其雄性不育发生的机制并更好地开发利用这一宝贵种质资源,我们从结构、生理和分子生物学等几个方面展开了研究。 本研究以可育系宁杞1号和不育系宁杞5号为实验材料,用超微结构、ATPase和Ca2+的细胞化学定位,以及转录组和数字基因表达谱研究了枸杞花药发育的特征并比较了不育花药形态 ...
杨淑娟
core  

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