Results 1 to 10 of about 26,514 (167)

食管癌组织中ADAMTS1、ADAMTS18基因mRNA的表达及其意义

open access: yesZhongguo shiyan zhenduanxue, 2021
目的探讨ADAMTS1和ADAMTS18基因在食管鳞状细胞癌组织中的表达及其与食管鳞状细胞癌临床病理特征的关系。方法应用半定量逆转录聚合酶链反应(RT-PCR)方法分别检测70例食管鳞状细胞癌组织及癌旁正常组织中ADAMTS1、ADAMTS18的mRNA表达,并分析基因表达与临床病理资料之间的关系。结果食管鳞状细胞癌组织中ADAMTS1、ADAMTS18基因的mRNA表达水平显著低于相应的癌旁正常组织(P0.05),ADAMTS1基因mRNA在有淋巴结转移组的表达量高于无淋巴结转移组(P0.05 ...
尹蕾   +5 more
doaj  

Proteomics and Expression of Immunity Related Genes Research in Fujian Oyster Under the Stress of Iron Salt and Vibrio Parahemolyticus [PDF]

open access: yes, 2016
牡蛎隶属于软体动物门(Mollusca)、双壳纲(Bivalvia)珍珠贝目(Pterio)。牡蛎具有很高的食用价值,现已成为中国乃至世界养殖产量最大的经济贝类。然而牡蛎养殖业面临着种种威胁,其中包括了病原体的感染。 铁是脊椎动物血红蛋白的重要组成成分,对机体免疫机制也具有重要作用。但铁对无脊椎动物免疫系统的影响鲜有研究。本论文以福建牡蛎为实验物种,以牡蛎的血淋巴和鳃为实验材料,选择铁盐为胁迫方法和诸多分析技术研究铁盐对牡蛎血淋巴和鳃产生的的影响。 本文采用3mg/L的铁盐胁迫牡蛎96小时 ...
张熠玮
core  

Representation of obligate groundwater‐dwelling copepod diversity in European protected areas

open access: yesConservation Biology, EarlyView.
Abstract Groundwaters sustain diverse surface ecosystems and are populated by metazoan species, mostly invertebrates, that provide fundamental ecological functions and are often of prominent conservation value due to narrow endemism and high phylogenetic rarity.
Francesco Cerasoli   +7 more
wiley   +1 more source

BAG Family Gene and Its Relationship with Lung Adenocarcinoma Susceptibility [PDF]

open access: yes, 2010
Background and objective BAG genes (Bcl-2-associated athanogene) belong to a recently discovered multifunctional anti-apoptosis gene family that regulate various physiological processes which include apoptosis, tumorigenesis, neural differentiation ...
Heng WU   +9 more
core  

Calibration of the species threat abatement and restoration metric's threat abatement component in a Costa Rican landscape

open access: yesConservation Biology, EarlyView.
Abstract Achieving global conservation policy goals requires the ability to set and measure progress toward science‐based targets for biodiversity. The species threat abatement and restoration (STAR) metric was developed to enable actors to set science‐based targets for species.
Louise Mair   +17 more
wiley   +1 more source

Functional Characterization of AtST39 in Stress Response and AtMPA Mediating Pollen Development [PDF]

open access: yes, 2012
基因芯片显示番茄细菌性叶斑病原菌Pseudomonassyringaepv.tomatoDC3000(PstDC3000),干旱、冷和盐等逆境处理及在开花关键基因lfy突变体中都能够上调AtST39(At3g46110)基因表达;AtMPA(At1g05577)在拟南芥单核花粉粒向三核花粉发育的过程中特异性表达。但是AtST39参与胁迫和AtMPA在介导花粉发育的分子机制知之甚少。我们主要对AtST39进行了探索研究,结果如下: (1)NCBI数据库显示YWC基因家族共有185个蛋白家族成员 ...
肖世民
core  

The vesicle trafficking R‐SNARE VAMP714 connects auxin responses, ROS and ion homeostasis in Arabidopsis under salt stress

open access: yesNew Phytologist, EarlyView.
Network of VAMP714‐dependent interactions during salt stress. Summary Plant responses to salt stress include an altered root architecture mediated by ion imbalances, reactive oxygen species (ROS) accumulation, and altered hormonal responses. Auxin is implicated in these processes.
Jialei Sun   +3 more
wiley   +1 more source

Classification of Gene Expression Data Based on Dimension Reduction [PDF]

open access: yes, 2015
利用基因芯片技术能够做到同时对多到数以万计的基因进行并行分析,随着该技术越来越成熟并得到广泛应用,现在已经有越来越多的基因表达数据测定出来,亟需处理,借助于计算机工具以及机器学习方法对这些大量数据进行分析是现在一个很重要的研究领域。其中,基因表达数据的分类研究是该领域的一个热点,通过分类能够帮助研究者发现正常细胞组织与疾病组织之间基因的本质差异,识别致病基因,对基因型疾病的临床诊断和治疗具有重要的意义。 基因表达数据具有“样本少、维数高、分布不平衡”的特点,这给分类带来了很多的困难和挑战 ...
李亮亮
core  

Implementation Punctuation: The Role of Feedback, Narratives, and Implementation in the Punctuated Equilibrium Theory

open access: yesPolicy Studies Journal, EarlyView.
ABSTRACT Based on the Punctuated Equilibrium Theory (PET) and implementation research, this study proposes an extended conceptualization of policy punctuation that enables researchers to systematically include policy implementation as part of a punctuation. The key mechanisms underlying the PET, i.e., policy image and venue, information processing, and
Bettina Stauffer
wiley   +1 more source

NFAT2 in the regulation of CAII and V-ATPase mRNA expression in osteoclast-like cells and intervention study of PEMF [PDF]

open access: yes, 2016
目的:研究低频脉冲电磁场(PEMF)对去卵巢大鼠核因子κB受体活化因子(RANK)、活化T细胞核因子(NFATc1/NFAT2)、碳酸酐酶II(CAII)、空泡型H+三磷酸腺苷转运酶(V-ATPase)基因表达的影响;研究NFAT2对CAII和V-ATPase基因表达的调控作用。 方法:1.选取48只雌性SD大鼠,分为三组,分别为SHAM(假手术)组、OVX(去卵巢)组、OVX+PEMF组,OVX+PEMF组随机选一半被PEMF干预14天和28天,测雌激素和骨密度。RT-PCR检测NFAT2、RANK ...
傅继凡
core  

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