ABSTRACTBreast cancer (BRCA) is one of the most common malignancies and a leading cause of cancer‐related mortality among women globally. Despite advances in diagnosis and treatment, the heterogeneity of BRCA presents significant challenges for effective management and prognosis. Recent studies emphasise the critical role of the tumour microenvironment,
Jie Xia, Xudong Zhou
wiley +4 more sources
Unravelling the role of PRKCI and key-cancer related genes in breast cancer development and metastasis [PDF]
Background Breast cancer is one of the most common causes of fatalities in females globally. Rising cases of drug resistance against existing chemotherapeutics are great problem.
Hania Shah +9 more
doaj +2 more sources
Herstellung und Reinigung von TPD52-Fusionsproteinen zur Proteintransduktion von Säugetierzellen
Die Chemokinrezeptoren CCR2a und CCR2b sind an der Regulation zentraler Funktionen von leukozytären Zellen beteiligt. In Untersuchungen wurde mit Tumorprotein D52 (TPD52) ein neuer Nicht-G-Protein-Interaktionspartner der CCR2 Rezeptoren identifiziert.
Schindler, Oliver
openaire +2 more sources
MicroRNA binding site variants–new potential markers of primary osteoporosis in men and women [PDF]
IntroductionThe identification of significant DNA markers of primary osteoporosis may gain new insights by studying genome regions involved in mechanisms of epigenetic regulation through interactions with microRNAs.MethodsThe authors searched for ...
Bulat Yalaev +9 more
doaj +2 more sources
Overexpression of TPD52L2 in HNSCC: prognostic significance and correlation with immune infiltrates [PDF]
Background Evidence has been presented that the tumor protein D52 (TPD52) family plays a critical role in tumor development and progression. As a member of the TPD52 family, the changes in TPD52L2 gene status are instrumental in kinds of cancer ...
Min Lu +5 more
doaj +2 more sources
Prognostic feature based on androgen-responsive genes in bladder cancer and screening for potential targeted drugs [PDF]
Objectives Bladder cancer (BLCA) is a tumor that affects men more than women. The biological function and prognostic value of androgen-responsive genes (ARGs) in BLCA are currently unknown.
Jiang Zhao +8 more
doaj +2 more sources
Circular RNA circEZH2 Promotes Lung Adenocarcinoma Progression by Regulating microRNA-495-3p/Tumor Protein D52 Axis and Activating Nuclear Factor-Kappa B Pathway [PDF]
Liping Chen,1 Tongwei Xiang,2 Jing Xing,2 Xinan Lu,2 Shan Wei,2 Huaying Wang,2 Jipeng Li,1 Wanjun Yu2 1Department of Central Laboratory, The Affiliated People’s Hospital of Ningbo University, Ningbo, People’s Republic of China; 2Department of Respiratory
Chen L +7 more
doaj +2 more sources
Retracted: MiR‐139‐5p Inhibits the Development of Gastric Cancer through Targeting TPD52 [PDF]
Engineering JOH.
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TPD52和TPD52L2在胃癌中异常表达的临床病理特征分析和相关基因共表达意义研究 附视频
目的 应用生物信息学的方法探讨肿瘤蛋白D52(tumor protein D52,TPD52)和肿瘤蛋白D52样2(tumor protein D52-like 2,TPD52L2)在胃癌中异常表达的临床病理特征,并分析相关基因共表达的意义。方法 基于癌症基因组图谱(The Cancer Genome AHas, TCGA)获取数据,利用R语言软件包比较TPD52和TPD52L2在胃癌组织和癌旁组织中的差异表达与临床病理特征的相关性,并探索与免疫细胞浸润水平的情况,Kaplan ...
doaj +2 more sources

