Cell & Bioscience, 2021 Background Tumor protein D52 (TPD52) reportedly plays an important role in the proliferation and metastasis of various cancer cells, including oral squamous cell carcinoma (OSCC) cells, and is expressed strongly at the center of the tumor, where the ...
Yuzo Abe +8 more
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Determining KLF14 tertiary structure and diagnostic significance in brain cancer progression
Scientific Reports, 2022 Expression analysis of new protein targets may play a crucial role in the early detection and diagnosis of brain tumor progression. The study aimed to investigate the possible relation of KLF14, TPD52, miR-124, and PKCĪµ in the development and progression
Kainat Zahra +9 more
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Long noncoding RNA FTX promotes epithelial-mesenchymal transition of epithelial ovarian cancer through modulating miR-7515/TPD52 and activating Met/Akt/mTOR [PDF]
, 2023 Overexpressed long noncoding RNA FTX is associated with low survival rate of epithelial ovarian cancer (EOC) patients, and enhances tumor infiltration. Thus, we aim to illuminate the undefined underlying mechanisms.
Xia, Fei +7 more
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TPD52 expression increases neutral lipid storage within cultured cells [PDF]
Journal of Cell Science, 2015 Tumor protein D52 (TPD52) is amplified/ over-expressed in cancers of diverse cellular origins. Altered cellular metabolism (including lipogenesis) is a hallmark of cancer development, and protein-protein associations between TPD52 and known regulators of lipid storage, and differential TPD52 expression in obese versus non-obese adipose tissue, suggest ...
Alvin, Kamili +11 more
openaire +2 more sources
Star-PAP regulates tumor protein D52 through modulating miR-449a/34a in breast cancer
Biology Open, 2019 Tumor protein D52 (TPD52) is an oncogene amplified and overexpressed in various cancers. Tumor-suppressive microRNA-449a and microRNA-34a (miR-449a/34a) were recently reported to inhibit breast cancer cell migration and invasion via targeting TPD52 ...
Aizhu Duan +5 more
doaj +1 more source
Tumor protein D52 (TPD52): A novel B-cell/plasma cell molecule with unique expression pattern and Ca2+-dependent association with Annexin VI. [PDF]
, 2005 We generated a murine monoclonal antibody (B28p) detecting an antigenic determinant shared by the immunoglobulin superfamily receptor translocationassociated 1 (IRTA1) receptor (the immunogen used to raise B28p) and an unrelated 28-kDa protein that
Carbone A. +22 more
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, 2022 Fig S3. A) Density plot representing the distribution of the percentage of positive cell for tumors in the BH cohort. As described in the manuscript text, three broad categories of tumors were identified: TPD52 negative (no positive cells, 54.9% of ...
Olga Zheludkova (10095056) +18 more
core +1 more source
GLUTAMINE DEPRIVATION EFFECT ON DEK, TPD52, BRCA1, ADGRE5, LIF, GNPDA1, AND COL6A1 GENE EXPRESSIONS IN IRE1 KNOCKDOWN U87 GLIOMA CELLS [PDF]
Biotechnologia Acta, 2017 To study effect of glutamine deprivation on the expression of genes encoding the key proliferation associated factors on a relation to inhibition of inositol requiring enzyme-1 IRE1 in U87 glioma cells was the aim of the research.
A. P. Kharkova +6 more
doaj +1 more source
Predicting 3D Structure, Cross Talks, and Prognostic Significance of KLF9 in Cervical Cancer
Frontiers in Oncology, 2022 Our study aimed to identify the new blood-based biomarkers for the diagnosis and prognosis of cervical cancer. Moreover, the three-dimensional (3D) structure of Kruppel-like factor 9 (KLF9) was also determined in order to better understand its function ...
Sadia Safi +11 more
doaj +1 more source
, 2022 Fig S4. Overall survival analysis by Kaplan Meier plotting of patients with Group 3/4 medulloblastoma (BH cohort), after stratification based on therapeutic approach and TPD52 IHC. Children in A-B were treated with chemotherapy-only protocols.
Olga Zheludkova (10095056) +18 more
core +1 more source