Results 41 to 50 of about 2,296 (190)

miR-103a-3p Suppresses Cell Proliferation and Invasion by Targeting Tumor Protein D52 in Prostate Cancer

open access: yesJournal of Investigative Surgery, 2021
Growing evidence points at an association between microRNAs and tumor development. Although dysregulation of microRNA-103a-3p (miR-103a-3p) in multiple human cancers has been reported, its expression in prostate cancer (PCa) remains unknown and there is ...
Jiyue Ge   +8 more
doaj   +1 more source

The detection, treatment, and biology of epithelial ovarian cancer [PDF]

open access: yes, 2010
Ovarian cancer is particularly insidious in nature. Its ability to go undetected until late stages coupled with its non-descript signs and symptoms make it the seventh leading cause of cancer related deaths in women.
Jennifer A.A. Gubbels   +4 more
core   +1 more source

Decreased microRNA-224 and its clinical significance in non-small cell lung cancer patients [PDF]

open access: yes, 2014
BACKGROUND: MicroRNA-224 has been proven dysregulated in some human malignancies and correlated with tumor progression. However, its expression and clinical significance in non–small cell lung cancer (NSCLC) is still unclear.
Dan Zhu   +6 more
core   +2 more sources

Folic Acid supplementary reduce the incidence of adenocarcinoma in a mouse model of colorectal cancer: microarray gene expression profile [PDF]

open access: yes, 2011
Background Whether Folic acid is a potential drug that may prevent the progression of colorectal carcinoma and when to use are important healthy issues we focus on.
Yan-Wei Lin   +7 more
core   +1 more source

MAL2 and tumor protein D52 (TPD52) are frequently overexpressed in ovarian carcinoma, but differentially associated with histological subtype and patient outcome

open access: yesBMC Cancer, 2010
Background The four-transmembrane MAL2 protein is frequently overexpressed in breast carcinoma, and MAL2 overexpression is associated with gain of the corresponding locus at chromosome 8q24.12.
Fanayan Susan   +11 more
doaj   +1 more source

Molecular Mechanisms of Nasal Epithelium in Rhinitis and Rhinosinusitis [PDF]

open access: yes, 2014
Peer ...
Fokkens, Wytske J.   +7 more
core   +4 more sources

GLUTAMINE DEPRIVATION EFFECT ON DEK, TPD52, BRCA1, ADGRE5, LIF, GNPDA1, AND COL6A1 GENE EXPRESSIONS IN IRE1 KNOCKDOWN U87 GLIOMA CELLS [PDF]

open access: yesBiotechnologia Acta, 2017
To study effect of glutamine deprivation on the expression of genes encoding the key proliferation associated factors on a relation to inhibition of inositol requiring enzyme-1 IRE1 in U87 glioma cells was the aim of the research.
A. P. Kharkova   +6 more
doaj   +1 more source

A role for tumor protein TPD52 phosphorylation in endo-membrane trafficking during cytokinesis [PDF]

open access: yesBiochemical and Biophysical Research Communications, 2010
Tumor protein D52 is expressed at high levels in exocrine cells containing large secretory granules where it regulates Ca(2+)-dependent protein secretion; however, D52 expression is also highly induced in multiple cancers. The present study investigated a role for the Ca(2+)-dependent phosphorylation of D52 at the single major phospho-acceptor site ...
Diana D H, Thomas   +4 more
openaire   +2 more sources

Predicting 3D Structure, Cross Talks, and Prognostic Significance of KLF9 in Cervical Cancer

open access: yesFrontiers in Oncology, 2022
Our study aimed to identify the new blood-based biomarkers for the diagnosis and prognosis of cervical cancer. Moreover, the three-dimensional (3D) structure of Kruppel-like factor 9 (KLF9) was also determined in order to better understand its function ...
Sadia Safi   +11 more
doaj   +1 more source

Prognostic Impact of miR-224 and RAS Mutations in Medullary Thyroid Carcinoma [PDF]

open access: yes, 2017
Little is known about the function of microRNA-224 (miR-224) in medullary thyroid cancer (MTC). This study investigated the role of miR-224 expression in MTC and correlated it with mutation status in sporadic MTCs.
BAROLLO, SUSI   +12 more
core   +3 more sources

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