Results 41 to 50 of about 1,427 (143)

Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells

Endocrine Regulations, 2020
Objective. The aim of the present study was to investigate the effect of adipokine NAMPT (nicotinamide phosphoribosyltransferase) silencing on the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other proliferation related ...
Tsymbal Daria O., Minchenko Dmytro O., Luzina Olena Y., Riabovol Olena O., Danilovskyi Serhiy V., Minchenko Oleksandr H.   +5 more
doaj   +1 more source

Hsa_circ_0007637 Facilitates Nasopharyngeal Carcinoma Progression by Sponging miR-636/TPD52 Axis

Cancer Management and Research, 2021
Yihong Wang,* Manyi Li,* Chen Pan,* Haiping Huang, Xiaoqing Hu, Jisheng Liu Department of Otolaryngology, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China*These authors contributed equally to this ...
Wang Y, Li M, Pan C, Huang H, Hu X, Liu J   +5 more
doaj  

Vaccination with a shared oncogenic tumor-self antigen elicits a population of CD8+ T cells with a regulatory phenotype

Human Vaccines & Immunotherapeutics, 2022
Cancer immunotherapy is a powerful tool for inducing antigen-specific antitumor cytotoxic T lymphocytes (CTLs). Next-generation strategies may include vaccination against overexpressed oncogenic tumor-self antigens.
C. Riccay Elizondo, Jennifer D. Bright, Robert K. Bright   +2 more
doaj   +1 more source

Figure S5 from Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study

, 2022
Fig S5. Progression free survival analysis by Kaplan Meier plotting of patients with Group 3/4 medulloblastoma (BH cohort), after stratification based on therapeutic approach and TPD52 IHC.
Olga Zheludkova (10095056), Daniel Schrimpf (4004783), Mariarita Santi (6741500), Poul H. Sorensen (10930186), Michael D. Taylor (6879950), Andrey Golanov (10095059), Christopher Dunham (10347151), Joanna Triscott (10347145), Konstantin Okonechnikov (3372758), Andrey Korshunov (4112119), Gian Luca Negri (14938607), David W. Ellison (15029558), Damian Stichel (459397), Andreas von Deimling (15037904), Stefan M. Pfister (14946090), Marcel Kool (86792), Marina Ryzhova (10095044), Vijay Ramaswamy (15037907), Alberto Delaidelli (5472752)   +18 more
core   +1 more source

miR-139-5p Was Identified as Biomarker of Different Molecular Subtypes of Breast Carcinoma

Frontiers in Oncology, 2022
Located on chromosome 11q13.4, miR-139-5p has been confirmed by several studies as a possible attractive biomarker for cancer, including breast cancer, but its mechanism of correlation in different molecular subtypes of breast cancer has not been ...
Haohang Sun, Ji Dai, Mengze Chen, Qi Chen, Qiong Xie, Weijun Zhang, Guoqing Li, Meidi Yan   +7 more
doaj   +1 more source

Herstellung und Reinigung von TPD52-Fusionsproteinen zur Proteintransduktion von Säugetierzellen

, 2012
Die Chemokinrezeptoren CCR2a und CCR2b sind an der Regulation zentraler Funktionen von leukozytären Zellen beteiligt. In Untersuchungen wurde mit Tumorprotein D52 (TPD52) ein neuer Nicht-G-Protein-Interaktionspartner der CCR2 Rezeptoren identifiziert ...
Schindler, Oliver
core   +1 more source

Figure S7 from Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study

, 2022
Fig S7. Estimated prediction error for overall survival based on models without TPD52 (blue lines) or with TPD52 (yellow lines), compared with the Kaplan-Meier benchmark (grey line).
Olga Zheludkova (10095056), Daniel Schrimpf (4004783), Mariarita Santi (6741500), Poul H. Sorensen (10930186), Michael D. Taylor (6879950), Andrey Golanov (10095059), Christopher Dunham (10347151), Joanna Triscott (10347145), Konstantin Okonechnikov (3372758), Andrey Korshunov (4112119), Gian Luca Negri (14938607), David W. Ellison (15029558), Damian Stichel (459397), Andreas von Deimling (15037904), Stefan M. Pfister (14946090), Marcel Kool (86792), Marina Ryzhova (10095044), Vijay Ramaswamy (15037907), Alberto Delaidelli (5472752)   +18 more
core   +1 more source

Promotive role of USP29-mediated deubiquitination in malignant proliferation of colorectal cancer cells via the KIAA1429/SOX8 axis

Biomolecules & Biomedicine, 2023
Colorectal cancer (CRC) is regarded as one of the most prevalent neoplasms worldwide, and ubiquitination and N6-methyladenosine (m6A) modification regulate the outgrowth of multiple cancers.
Juncai Li, Jianguo Yang, Zhenzhou Chen, Li Liu, Hao Wang, Qican Deng, Yajun Chen, Yong Que, Zhongxue Fu   +8 more
doaj   +1 more source

Androgen receptor and its splice variant, AR-V7, differentially induce mRNA splicing in prostate cancer cells

Scientific Reports, 2021
Prostate cancer (PCa) is dependent on the androgen receptor (AR). Advanced PCa is treated with an androgen deprivation therapy-based regimen; tumors develop resistance, although they typically remain AR-dependent.
Manjul Rana, Jianrong Dong, Matthew J. Robertson, Cristian Coarfa, Nancy L. Weigel   +4 more
doaj   +1 more source

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

VIEW, Volume 7, Issue 3, June 2026.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai, Tianming Peng, Zhiyue Xie, Chuqian Zhen, Chen Yao, Nan Peng, Qianyi Li, Yuzhong Yu, Jiming Bao, Xian‐Lu Song, Mingkun Chen, Shan‐Chao Zhao   +11 more
wiley   +1 more source