Results 21 to 30 of about 1,427 (143)

miR-103a-3p Suppresses Cell Proliferation and Invasion by Targeting Tumor Protein D52 in Prostate Cancer

Journal of Investigative Surgery, 2021
Growing evidence points at an association between microRNAs and tumor development. Although dysregulation of microRNA-103a-3p (miR-103a-3p) in multiple human cancers has been reported, its expression in prostate cancer (PCa) remains unknown and there is ...
Jiyue Ge, Likai Mao, Weiqiang Xu, Wenge Fang, Ningning Wang, Dawen Ye, Zhuang Dong, Han Guan, Chao Guan   +8 more
doaj   +2 more sources

MicroRNA binding site variants–new potential markers of primary osteoporosis in men and women [PDF]

Frontiers in Genetics
IntroductionThe identification of significant DNA markers of primary osteoporosis may gain new insights by studying genome regions involved in mechanisms of epigenetic regulation through interactions with microRNAs.MethodsThe authors searched for ...
Bulat Yalaev, Roman Deev, Anton Tyurin, Ramil Salakhov, Kirill Smirnov, Anna Eremkina, Natalia Mokrysheva, Ildar Minniakhmetov, Rita Khusainova, Rita Khusainova   +9 more
doaj   +2 more sources

Circular RNA circEZH2 Promotes Lung Adenocarcinoma Progression by Regulating microRNA-495-3p/Tumor Protein D52 Axis and Activating Nuclear Factor-Kappa B Pathway [PDF]

International Journal of General Medicine
Liping Chen,1 Tongwei Xiang,2 Jing Xing,2 Xinan Lu,2 Shan Wei,2 Huaying Wang,2 Jipeng Li,1 Wanjun Yu2 1Department of Central Laboratory, The Affiliated People’s Hospital of Ningbo University, Ningbo, People’s Republic of China; 2Department of Respiratory
Chen L, Xiang T, Xing J, Lu X, Wei S, Wang H, Li J, Yu W   +7 more
doaj   +2 more sources

Identification of lncRNA, miRNA and mRNA expression profiles and ceRNA Networks in small cell lung cancer [PDF]

BMC Genomics, 2023
Background Small cell lung cancer (SCLC) is a highly lethal malignant tumor. It accounts for approximately 15% of newly diagnosed lung cancers.
Chenxi Zhang, Ying Zhou, Bin Zhang, Zhihong Sheng, Nan Sun, Baiyin Yuan, Xiaoyuan Wu   +6 more
doaj   +2 more sources

Overexpression of TPD52L2 in HNSCC: prognostic significance and correlation with immune infiltrates [PDF]

BMC Oral Health
Background Evidence has been presented that the tumor protein D52 (TPD52) family plays a critical role in tumor development and progression. As a member of the TPD52 family, the changes in TPD52L2 gene status are instrumental in kinds of cancer ...
Min Lu, Haoyu Xia, Jing Xu, Zijun Liao, Yuwen Li, Hanwei Peng   +5 more
doaj   +2 more sources

Prognostic feature based on androgen-responsive genes in bladder cancer and screening for potential targeted drugs [PDF]

BioData Mining
Objectives Bladder cancer (BLCA) is a tumor that affects men more than women. The biological function and prognostic value of androgen-responsive genes (ARGs) in BLCA are currently unknown.
Jiang Zhao, Qian Zhang, Cunle Zhu, Wu Yuqi, Guohui Zhang, Qianliang Wang, Xingyou Dong, Benyi Li, Xiangwei Wang   +8 more
doaj   +2 more sources

AMPK targets a proto-oncogene TPD52 (isoform 3) expression and its interaction with LKB1 suppress AMPK-GSK3β signaling axis in prostate cancer [PDF]

Journal of Cell Communication and Signaling, 2023
Ramesh Ummanni, Surender Singh Jadav
exaly   +2 more sources

Tumor protein D52 is upregulated in oral squamous carcinoma cells under hypoxia in a hypoxia-inducible-factor-independent manner and is involved in cell death resistance

Cell & Bioscience, 2021
Background Tumor protein D52 (TPD52) reportedly plays an important role in the proliferation and metastasis of various cancer cells, including oral squamous cell carcinoma (OSCC) cells, and is expressed strongly at the center of the tumor, where the ...
Yuzo Abe, Yoshiki Mukudai, Mai Kurihara, Asami Houri, Junichiro Chikuda, Atsutoshi Yaso, Kosuke Kato, Toshikazu Shimane, Tatsuo Shirota   +8 more
doaj   +1 more source

Anti-osteosarcoma effect of antiserum against cross antigen TPD52 between osteosarcoma and Trichinella spiralis

Parasites & Vectors, 2021
Background Trichinella spiralis (T. spiralis) is a parasite occurring worldwide that has been proven to have antitumour ability. However, studies on the antitumour effects of cross antigens between the tumour and T.
Tao-Tao Yue, Nan Zhang, Jian-Hua Li, Xiang-Yun Lu, Xiao-Cen Wang, Xin Li, Hong-Bo Zhang, Shu-Qin Cheng, Bo-Bo Wang, Peng-Tao Gong, Xi-Chen Zhang   +10 more
doaj   +1 more source

Determining KLF14 tertiary structure and diagnostic significance in brain cancer progression

Scientific Reports, 2022
Expression analysis of new protein targets may play a crucial role in the early detection and diagnosis of brain tumor progression. The study aimed to investigate the possible relation of KLF14, TPD52, miR-124, and PKCε in the development and progression
Kainat Zahra, Maria Shabbir, Yasmin Badshah, Janeen H. Trembley, Zunaira Badar, Khushbukhat Khan, Tayyaba Afsar, Ali Almajwal, Nawaf W. Alruwaili, Suhail Razak   +9 more
doaj   +1 more source