Results 21 to 30 of about 1,428 (171)

TPD52 (tumor protein D52) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on TPD52 (tumor protein D52), with data on DNA, on the protein encoded, and where the gene is implicated.
Della-Franca, A, Byrne, J
openaire   +3 more sources

The four-transmembrane protein MAL2 and tumor protein D52 (TPD52) are highly expressed in colorectal cancer and correlated with poor prognosis. [PDF]

PLoS ONE, 2017
The four-transmembrane protein MAL2 and tumor protein D52 (TPD52) have been shown to be involved in tumorigenesis of various cancers. However, their roles in colorectal cancer (CRC) remain unclear.
Jingwen Li, Yongmin Li, He Liu, Yanlong Liu, Binbin Cui   +4 more
doaj   +2 more sources

Anti-osteosarcoma effect of antiserum against cross antigen TPD52 between osteosarcoma and Trichinella spiralis [PDF]

Parasites & Vectors, 2021
Background Trichinella spiralis (T. spiralis) is a parasite occurring worldwide that has been proven to have antitumour ability. However, studies on the antitumour effects of cross antigens between the tumour and T.
Tao-Tao Yue, Nan Zhang, Jian-Hua Li, Xiang-Yun Lu, Xiao-Cen Wang, Xin Li, Hong-Bo Zhang, Shu-Qin Cheng, Bo-Bo Wang, Peng-Tao Gong, Xi-Chen Zhang   +10 more
doaj   +3 more sources

Tissue microarray profiling and integrative proteomics indicate the modulatory potential of Maytenus royleanus in inhibition of overexpressed TPD52 in prostate cancers

Scientific Reports, 2021
Maytenus roylanus (MEM) is a plant with anti-proliferative effects against prostate cancer. We aimed to explore the mechanism of action of MEM in prostate cancer (PCa) by employing an in vitro global proteome approach to get useful information of various
Maria Shabbir, Hasan Mukhtar, Deeba Syed, Suhail Razak, Tayyaba Afsar, Ali Almajwal, Yasmin Badshah, Dara Aldisi   +7 more
doaj   +2 more sources

MAL2 and tumor protein D52 (TPD52) are frequently overexpressed in ovarian carcinoma, but differentially associated with histological subtype and patient outcome

BMC Cancer, 2010
Background The four-transmembrane MAL2 protein is frequently overexpressed in breast carcinoma, and MAL2 overexpression is associated with gain of the corresponding locus at chromosome 8q24.12.
Fanayan Susan, Scurry James P, Murali Rajmohan, Gloss Brian S, Hardy Jayne R, Maleki Sanaz, Byrne Jennifer A, Emmanuel Catherine, Hacker Neville F, Sutherland Robert L, deFazio Anna, O'Brien Philippa M   +11 more
doaj   +2 more sources

Hsa_circ_0007637 Facilitates Nasopharyngeal Carcinoma Progression by Sponging miR-636/TPD52 Axis

Cancer Management and Research, 2021
Yihong Wang,* Manyi Li,* Chen Pan,* Haiping Huang, Xiaoqing Hu, Jisheng Liu Department of Otolaryngology, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China*These authors contributed equally to this ...
Wang Y, Li M, Pan C, Huang H, Hu X, Liu J   +5 more
doaj   +4 more sources

Tumor protein D52 (isoform 3) contributes to prostate cancer cell growth via targeting nuclear factor-κB transactivation in LNCaP cells

Tumor Biology, 2017
Our previous study showed that TPD52 overexpression could increase migration and proliferation of LNCaP cells contributing to the development of prostate cancer.
Chandrashekhar Dasari, Dattu Prasad Yaghnam, Reinhard Walther, Ramesh Ummanni   +3 more
doaj   +2 more sources

Cross talk of tumor protein D52 (TPD52) with KLF9, PKCε, and MicroRNA 223 in ovarian cancer [PDF]

Journal of Ovarian Research, 2023
Background Gynecologic cancers comprise malignancies in the female reproductive organs. Ovarian cancer ranks sixth in terms of incidence rates while seventh in terms of mortality rates. The stage at which ovarian cancer is diagnosed mainly determines the
Khushbukhat Khan, Sameen Zafar, Yasmin Badshah, Naeem Mahmood Ashraf, Mehak Rafiq, Lubna Danish, Maria Shabbir, Janeen H. Trembley, Tayyaba Afsar, Ali Almajwal, Suhail Razak   +10 more
doaj   +2 more sources

Tumor protein D52 (TPD52) and cancer—oncogene understudy or understudied oncogene?

Tumor Biology, 2014
The Tumor protein D52 (TPD52) gene was identified nearly 20 years ago through its overexpression in human cancer, and a substantial body of data now strongly supports TPD52 representing a gene amplification target at chromosome 8q21.13. This review updates progress toward understanding the significance of TPD52 overexpression and targeting, both in ...
Jennifer A Byrne, Yuyan Chen, Robert K Bright   +2 more
exaly   +3 more sources

Unpacking the Tumor Protein D52-like Family: Roles in Intracellular Trafficking and Cancer Progression [PDF]

Cells
There is growing evidence that dysregulation of vesicle-mediated intracellular trafficking pathways leads to the development of various diseases, including cancer. Cancer exploits the intracellular trafficking pathways to modulate the protein flow, alter
Emma L. Dorward, Michael Ortiz, Claire M. Weekley, Kay K. Myo Min, Pascal H. G. Duijf, S. George Barreto, Michael W. Parker, Claudine S. Bonder   +7 more
doaj   +2 more sources