Results 51 to 60 of about 1,428 (171)

A role for tumor protein TPD52 phosphorylation in endo-membrane trafficking during cytokinesis [PDF]

Biochemical and Biophysical Research Communications, 2010
Tumor protein D52 is expressed at high levels in exocrine cells containing large secretory granules where it regulates Ca(2+)-dependent protein secretion; however, D52 expression is also highly induced in multiple cancers. The present study investigated a role for the Ca(2+)-dependent phosphorylation of D52 at the single major phospho-acceptor site ...
Diana D H, Thomas, Christina L, Frey, Scott W, Messenger, Benjamin K, August, Guy E, Groblewski   +4 more
openaire   +2 more sources

Additional file 3 of Anti-osteosarcoma effect of antiserum against cross antigen TPD52 between osteosarcoma and Trichinella spiralis

, 2021
Additional file 3: Table S3. Anti-TPD52 antiserum titre detection (OD450)
Hong-Bo Zhang (1351680), Xin Li (51274), Shu-Qin Cheng (11482164), Xi-Chen Zhang (8062079), Peng-Tao Gong (8062070), Xiao-Cen Wang (8062076), Tao-Tao Yue (11482158), Nan Zhang (46264), Bo-Bo Wang (11482167), Jian-Hua Li (85475), Xiang-Yun Lu (11482161)   +10 more
core   +1 more source

Expression of tumor growth related genes in IRE1 knockdown U87 glioma cells: effect of hypoxia [PDF]

The Ukrainian Biochemical Journal, 2017
We have studied the effect of IRE1 signaling enzyme knockdown as well as hypoxia on the expression of genes encoding the important tumor growth related proteins (BRCA1, DEK, BCL2L1, COL6A1, TPD52, HOMER3, and GNPDA1) in U87 glioma cells.
O. H. Minchenko, O. Y. Luzina, O. S. Hnatiuk, D. O. Minchenko, I. A. Garmash, O. O. Ratushna   +5 more
doaj   +1 more source

Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells

Endocrine Regulations, 2020
Objective. The aim of the present study was to investigate the effect of adipokine NAMPT (nicotinamide phosphoribosyltransferase) silencing on the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other proliferation related ...
Tsymbal Daria O., Minchenko Dmytro O., Luzina Olena Y., Riabovol Olena O., Danilovskyi Serhiy V., Minchenko Oleksandr H.   +5 more
doaj   +1 more source

Decreased TPD52 expression is associated with poor prognosis in primary hepatocellular carcinoma

Oncotarget, 2015
Tumor protein D52 (TPD52) has been indicated to be involved in tumorigenesis of various malignancies. But its role in hepatocellular carcinoma (HCC) is unknown. This study aimed to explore the expression of TPD52 in HCC samples and cell lines using real-time quantitative PCR, western blotting, and immunohistochemistry.
Wang, Ying, Chen, Chang-Long, Pan, Qiu-Zhong, Wu, Ying-Yuan, Zhao, Jing-Jing, Jiang, Shan-Shan, Chao, Jie, Zhang, Xiao-Fei, Zhang, Hong-Xia, Zhou, Zi-Qi, Tang, Yan, Huang, Xu-Qiong, Zhang, Jian-Hua, Xia, Jian-Chuan   +13 more
openaire   +3 more sources

Figure S7 from Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study

, 2022
Fig S7. Estimated prediction error for overall survival based on models without TPD52 (blue lines) or with TPD52 (yellow lines), compared with the Kaplan-Meier benchmark (grey line).
Olga Zheludkova (10095056), Daniel Schrimpf (4004783), Mariarita Santi (6741500), Poul H. Sorensen (10930186), Michael D. Taylor (6879950), Andrey Golanov (10095059), Christopher Dunham (10347151), Joanna Triscott (10347145), Konstantin Okonechnikov (3372758), Andrey Korshunov (4112119), Gian Luca Negri (14938607), David W. Ellison (15029558), Damian Stichel (459397), Andreas von Deimling (15037904), Stefan M. Pfister (14946090), Marcel Kool (86792), Marina Ryzhova (10095044), Vijay Ramaswamy (15037907), Alberto Delaidelli (5472752)   +18 more
core   +1 more source

Intracellular nanovesicles mediate α5β1 integrin trafficking during cell migration [PDF]

, 2021
Membrane traffic is an important regulator of cell migration through the endocytosis and recycling of cell surface receptors such as integrin heterodimers.
Stephen J. Royle, Caswell, PT, Hetmanski, JHR, Méghane Sittewelle, Caswell, Patrick T., Royle, SJ, Larocque, G, Hetmanski, Joseph H.R., Sittewelle, Méghane, Larocque, Gabrielle, Clarke, Nicholas I., Penelope J. La-Borde, Patrick T. Caswell, Moore, Daniel J., Daniel J. Moore, Hetmanski, Joseph H. R., Joseph H.R. Hetmanski, Clarke, NI, Kuey, Cansu, Wilson, BJ, Moore, DJ, Cansu Kuey, Caswell, Patrick T.; id_orcid, Kuey, C, Royle, Stephen J., La-Borde, Penelope J., Nicholas I. Clarke, Gabrielle Larocque, Wilson, Beverley J., Sittewelle, M, Beverley J. Wilson, La-Borde, PJ   +31 more
core   +1 more source

Figure S5 from Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study

, 2022
Fig S5. Progression free survival analysis by Kaplan Meier plotting of patients with Group 3/4 medulloblastoma (BH cohort), after stratification based on therapeutic approach and TPD52 IHC.
Olga Zheludkova (10095056), Daniel Schrimpf (4004783), Mariarita Santi (6741500), Poul H. Sorensen (10930186), Michael D. Taylor (6879950), Andrey Golanov (10095059), Christopher Dunham (10347151), Joanna Triscott (10347145), Konstantin Okonechnikov (3372758), Andrey Korshunov (4112119), Gian Luca Negri (14938607), David W. Ellison (15029558), Damian Stichel (459397), Andreas von Deimling (15037904), Stefan M. Pfister (14946090), Marcel Kool (86792), Marina Ryzhova (10095044), Vijay Ramaswamy (15037907), Alberto Delaidelli (5472752)   +18 more
core   +1 more source

Vaccination with a shared oncogenic tumor-self antigen elicits a population of CD8+ T cells with a regulatory phenotype

Human Vaccines & Immunotherapeutics, 2022
Cancer immunotherapy is a powerful tool for inducing antigen-specific antitumor cytotoxic T lymphocytes (CTLs). Next-generation strategies may include vaccination against overexpressed oncogenic tumor-self antigens.
C. Riccay Elizondo, Jennifer D. Bright, Robert K. Bright   +2 more
doaj   +1 more source

miR-139-5p Was Identified as Biomarker of Different Molecular Subtypes of Breast Carcinoma

Frontiers in Oncology, 2022
Located on chromosome 11q13.4, miR-139-5p has been confirmed by several studies as a possible attractive biomarker for cancer, including breast cancer, but its mechanism of correlation in different molecular subtypes of breast cancer has not been ...
Haohang Sun, Ji Dai, Mengze Chen, Qi Chen, Qiong Xie, Weijun Zhang, Guoqing Li, Meidi Yan   +7 more
doaj   +1 more source