Results 51 to 60 of about 2,296 (190)

Combining Genome Wide Association Studies and Differential Gene Expression Data Analyses Identifies Candidate Genes Affecting Mastitis Caused by Two Different Pathogens in the Dairy Cow [PDF]

open access: yes, 2015
Mastitis is a costly disease which hampers the dairy industry. Inflammation of the mammary gland is commonly caused by bacterial infection, mainly Escherichia coli, Streptococcus uberis and Staphylococcus aureus.
Chen, X   +4 more
core   +3 more sources

miR-107 enhances the sensitivity of breast cancer cells to paclitaxel

open access: yesOpen Medicine, 2019
Breast cancer remains the most commonly diagnosed cancer in Chinese women. Paclitaxel (PTX) is a chemotherapy medication used to treat breast cancer patients. However, a side effect of paclitaxel is the severe drug resistance.
Ma Changpo   +4 more
doaj   +1 more source

Expression of tumor growth related genes in IRE1 knockdown U87 glioma cells: effect of hypoxia [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2017
We have studied the effect of IRE1 signaling enzyme knockdown as well as hypoxia on the expression of genes encoding the important tumor growth related proteins (BRCA1, DEK, BCL2L1, COL6A1, TPD52, HOMER3, and GNPDA1) in U87 glioma cells.
O. H. Minchenko   +5 more
doaj   +1 more source

Adaptive Huber Regression [PDF]

open access: yes, 2018
Big data can easily be contaminated by outliers or contain variables with heavy-tailed distributions, which makes many conventional methods inadequate.
Fan, Jianqing, Sun, Qiang, Zhou, Wenxin
core   +2 more sources

Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells

open access: yesEndocrine Regulations, 2020
Objective. The aim of the present study was to investigate the effect of adipokine NAMPT (nicotinamide phosphoribosyltransferase) silencing on the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other proliferation related ...
Tsymbal Daria O.   +5 more
doaj   +1 more source

Decreased TPD52 expression is associated with poor prognosis in primary hepatocellular carcinoma

open access: yesOncotarget, 2015
Tumor protein D52 (TPD52) has been indicated to be involved in tumorigenesis of various malignancies. But its role in hepatocellular carcinoma (HCC) is unknown. This study aimed to explore the expression of TPD52 in HCC samples and cell lines using real-time quantitative PCR, western blotting, and immunohistochemistry.
Wang, Ying   +13 more
openaire   +3 more sources

Nonredundant Functions for Tumor Protein D52-Like Proteins Support Specific Targeting of TPD52 [PDF]

open access: yesClinical Cancer Research, 2008
Abstract Purpose: Tumor protein D52 (TPD52 or D52) is frequently overexpressed in breast and other cancers and present at increased gene copy number. It is, however, unclear whether D52 amplification and overexpression target specific functional properties of the encoded protein.
Shehata, M.   +10 more
openaire   +3 more sources

Randomness and preserved patterns in cancer network

open access: yes, 2014
Breast cancer has been reported to account for the maximum cases among all female cancers till date. In order to gain a deeper insight into the complexities of the disease, we analyze the breast cancer network and its normal counterpart at the proteomic ...
Jalan, Sarika   +2 more
core   +1 more source

Vaccination with a shared oncogenic tumor-self antigen elicits a population of CD8+ T cells with a regulatory phenotype

open access: yesHuman Vaccines & Immunotherapeutics, 2022
Cancer immunotherapy is a powerful tool for inducing antigen-specific antitumor cytotoxic T lymphocytes (CTLs). Next-generation strategies may include vaccination against overexpressed oncogenic tumor-self antigens.
C. Riccay Elizondo   +2 more
doaj   +1 more source

miR-139-5p Was Identified as Biomarker of Different Molecular Subtypes of Breast Carcinoma

open access: yesFrontiers in Oncology, 2022
Located on chromosome 11q13.4, miR-139-5p has been confirmed by several studies as a possible attractive biomarker for cancer, including breast cancer, but its mechanism of correlation in different molecular subtypes of breast cancer has not been ...
Haohang Sun   +7 more
doaj   +1 more source

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