Results 71 to 80 of about 1,427 (143)
Abstract Circulating extracellular vesicles and particles (EVPs) are being investigated as potential biomarkers for early cancer detection, prognosis, and disease monitoring. However, the suboptimal purity of EVPs isolated from peripheral blood plasma has posed a challenge of in‐depth analysis of the EVP proteome. Here, we compared the effectiveness of
Zurong Wan +16 more
wiley +1 more source
Objective Tumor protein D52 (TPD52) is aberrantly expressed in various malignancies; however, its systematic expression profile, prognostic significance, tumor microenvironment associations, and functional mechanisms in breast cancer ...
Zhenyu Zhu +7 more
core +1 more source
TPD52: functional elucidation of a novel lipid droplet binding protein in human hepatocytes
Lipid droplets (LDs) are intracellular vesicles involved in the storage of triglycerides (TG) and cholesteryl ester (CE). Although LDs are used for storage, they also play a dynamic role in cell metabolism.
Feng, Shi Bo
core
Prävalenz und klinische Signifikanz von TPD52-Gen-Amplifikationen im humanen Prostatakarzinom
Das Prostatakarzinom ist das am häufigsten diagnostizierte Malignom bei Männern in den Industrienationen. Die molekularen Prozesse, welche die Entstehung dieser Tumorentität begünstigen, gilt es zu identifizieren und für die klinische Routine zu nutzen ...
Rohwer, Julia Carolin
core
Nonredundant functions for tumor protein D52-like proteins support specific targeting of TPD52
Purpose: Tumor protein D52 (TPD52 or D52) is frequently overexpressed in breast and other cancers and present at increased gene copy number. It is, however, unclear whether D52 amplification and overexpression target specific functional properties of the
J. Weidenhofer (23344774) +10 more
core +2 more sources
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Daoqing Su, Zhengang Ji, Pengfei Xue, Shengfu Guo, Qingbin Jia, Hanyu Sun Department of Neurosurgery, Liaocheng People’s Hospital and Liaocheng Brain Hospital, Liaocheng Hospital Affiliated to Shandong First Medical University, Liaocheng City ...
Su D, Ji Z, Xue P, Guo S, Jia Q, Sun H
doaj
Inhibiting Tumor Protein D52 function for anti-cancer therapy application [PDF]
Tumor protein D52 (TPD52) is amplified and/or overexpressed in many cancer types. Previously, TPD52 expression has been associated with ERBB2, suggesting these oncogenes may co-operate in cancer pathogenesis.
Roslan, Nuruliza
core
Widespread alternative exon usage in clinically distinct subtypes of Invasive Ductal Carcinoma
Cancer cells can have different patterns of exon usage of individual genes when compared to normal tissue, suggesting that alternative splicing may play a role in shaping the tumor phenotype.
Sunniva Stordal Bjørklund +14 more
doaj +1 more source
Background: Androgen steroid hormones are key drivers of prostate cancer. Previous work has shown that androgens can drive the expression of alternative mRNA isoforms as well as transcriptional changes in prostate cancer cells.
Jennifer Munkley +9 more
doaj +1 more source

