Results 91 to 100 of about 2,296 (190)
Clinical and Translational Medicine, Volume 14, Issue 2, February 2024.AIDPI is a robust biomarker for stratifying high‐risk OSA patients characterized by dysregulated cholesterol homeostasis, and SQLE is a metabolic vulnerability of these patients. Silencing SQLE impedes OSA by reducing cholesterol and inhibiting the FAK/PI3K/Akt/mTOR pathway.
Yongjie Wang +7 more
wiley +1 more source
Functional significance of Tumor Protein D52 amplification and overexpression in cancer [PDF]
, 2018 Tumor Protein D52 (TPD52) is an oncogene whose overexpression has been demonstrated in tumours of diverse cellular origins and associated with poor prognosis.
Frost, Sarah
core
Inter-individual variation in DNA repair capacity: A need for multi-pathway functional assays to promote translational DNA repair research [PDF]
, 2014 Why does a constant barrage of DNA damage lead to disease in some individuals, while others remain healthy? This article surveys current work addressing the implications of inter-individual variation in DNA repair capacity for human health, and discusses
Chaim, Isaac Alexander +2 more
core +1 more source
Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Exome-wide association study of pancreatic cancer risk [PDF]
, 2018 We conducted a case-control exome-wide association study to discover germline variants in coding regions that affect risk for pancreatic cancer, combining data from 5 studies. We analyzed exome and genome sequencing data from 437 patients with pancreatic
Biankin, Andrew +18 more
core +1 more source
Improved resistance to Eimeria acervulina infection in chickens due to dietary supplementation with garlic metabolites [PDF]
, 2017 The effects of a compound including the secondary metabolites of garlic, propyl thiosulphinate (PTS) and propyl thiosulphinate oxide (PTSO), on the in vitro and in vivo parameters of chicken gut immunity during experimental Eimeria acervulina infection ...
Bravo, David +4 more
core
Cancer Management and Research, 2020 Daoqing Su, Zhengang Ji, Pengfei Xue, Shengfu Guo, Qingbin Jia, Hanyu Sun Department of Neurosurgery, Liaocheng People’s Hospital and Liaocheng Brain Hospital, Liaocheng Hospital Affiliated to Shandong First Medical University, Liaocheng City ...
Su D, Ji Z, Xue P, Guo S, Jia Q, Sun H
doaj
Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]
, 2008 Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama +4 more
core +1 more source
Tumor Proteins D52 and D54 Have Opposite Effects on the Terminal Differentiation of Chondrocytes [PDF]
, 2017 The tumor protein D (TPD) family consists of four members, TPD52, TPD53, TPD54, and TPD55. The physiological roles of these genes in normal tissues, including epidermal and mesenchymal tissues, have rarely been reported.
Chihiro Ito +7 more
core +2 more sources
Calcium‐dependent phosphorylation of TPD52 is mediated by a novel 46 kDa CAMKII isoform
The FASEB Journal, 2008 In the GI tract, tumor protein D52 is highly expressed in cells that undergo classical exocytosis and has been implicated as a regulator of this process. We have shown that the cholinergic agonist, carbachol, and the calcium ionophore, ionomycin, increase the phosphorylation of S136 in the D52 protein in gastric mucosal cells.
Catherine S. Chew +3 more
openaire +1 more source