Results 81 to 90 of about 1,427 (143)

Tumor protein D52 expression is post-transcriptionally regulated by T-cell intercellular antigen (TIA) 1 and TIA-related protein via mRNA stability

, 2017
Although tumor protein D52 (TPD52) family proteins were first identified nearly 20 years ago, their molecular regulatory mechanisms remain unclear. Therefore, we investigated the post-transcriptional regulation of TPD52 family genes.
Yoshiki Mukudai, Seiji Kondo, Tatsuo Shirota, Chihiro Ito, Toshikazu Shimane, Hiromi Motohashi, Kosuke Kato   +6 more
core   +1 more source

Functional significance of Tumor Protein D52 amplification and overexpression in cancer [PDF]

, 2018
Tumor Protein D52 (TPD52) is an oncogene whose overexpression has been demonstrated in tumours of diverse cellular origins and associated with poor prognosis.
Frost, Sarah
core  

Differentially expressed proteins in prostate cancer and functional characterization of proteins with altered expression [PDF]

, 2008
Summary Prostate cancer (PCa) is the most common type of cancer found in men from western countries and is the leading cancer death next to lung cancer and colorectal cancer.
Ummanni, Ramesh
core   +1 more source

Late‐breaking trials in IBD

United European Gastroenterology Journal, Volume 13, Issue 9, Page 1818-1839, November 2025.
wiley   +1 more source

Role of tumor protein D52 in tumor occurrence and development, and its potential application value in tumor diagnosis and therapy [PDF]

, 2016
肿瘤蛋白D52(TPD52)在乳腺癌、前列腺癌、肺癌、卵巢癌和血液系统恶性病变等多种肿瘤中高表达,可参与肿瘤细胞增殖、侵袭、转移以及抑制DNA修复等生物学行为,并诱导机体产生对肿瘤的保护性免疫,是肿瘤诊断与分子靶向治疗中最有应用前景的候选蛋白之一。笔者对TPD52在肿瘤中发生发展的作用及其在肿瘤诊疗中潜在应用价值进行综述,旨在为TPD52进一步研究指明方向,更好实现其临床价值。Tumor protein D52(TPD52), which is involved in tumor cell ...
骆明旭, 周思佳, 陈波
core  

TPD52和TPD52L2在胃癌中异常表达的临床病理特征分析和相关基因共表达意义研究

Zhongguo shiyan zhenduanxue
目的 应用生物信息学的方法探讨肿瘤蛋白D52(tumor protein D52,TPD52)和肿瘤蛋白D52样2(tumor protein D52-like 2,TPD52L2)在胃癌中异常表达的临床病理特征，并分析相关基因共表达的意义。方法 基于癌症基因组图谱(The Cancer Genome AHas, TCGA)获取数据，利用R语言软件包比较TPD52和TPD52L2在胃癌组织和癌旁组织中的差异表达与临床病理特征的相关性，并探索与免疫细胞浸润水平的情况，Kaplan ...
高夏青, 杨春婷, 郭双铭, 韩静, 樊涛, 杨霄, 李海龙   +6 more
doaj  

Abstract 4791: Inhibition of Tumor Formation in Mice following Vaccination with DNA Encoding a Novel Xenogeneic Tumor Associated Auto-Antigen

, 2010
Tumor protein D52 (TPD52) is a novel auto-antigen involved in cellular transformation, proliferation and metastasis. Its over-expression has been demonstrated in several human malignancies including prostate, breast, and ovarian carcinomas. Murine TPD52 (
Heather N. Schultz, Robert K. Bright, Jennifer D. Bright   +2 more
core   +1 more source

mRNA levels of Sparc, LRIG1, TPD52, EGLN2, and CCND1 as measured by QRT–PCR in the P+R and R+P cells and proteins levels of these differentially expressed genes as measured by immunohistochemistry in tissues formed from transplanted P+R and R+P cells.

, 2012
Between parentheses, is indicated the fold change of expression levels of these genes as determined by microarray analysis between P+R and R+P cell populations (see Table S1). Relative expression levels normalized to RP-L27 were determined using specific
Aude Salomon (165875), Jean-Jacques Feige (158745), Michaël Thomas (5649268), Maryline Herbet (165871)   +3 more
core   +1 more source

Abstract Book

HemaSphere, Volume 8, Issue S2, October 2024.
wiley   +1 more source

The hD52 (TPD52) gene is a candidate target gene for events resulting in increased 8q21 copy number in human breast carcinoma

, 2000
International audienceChromosome band 8q21 is frequently overrepresented in human cancer, but to date no 8q21 target gene has been proposed. The hD52 (TPD52) gene is of potential significance in breast and other cancers due to its location and expression
Fejzo, Marlena Schoenberg, Clarke, Christine, Byrne, Jennifer, Balleine, Rosemary, Sathasivam, Pavani, Basset, Paul   +5 more
core   +1 more source