Results 61 to 70 of about 2,296 (190)
Overlapping synthetic peptides encoding TPD52 as breast cancer vaccine in mice: Prolonged survival [PDF]
Vaccine, 2009 Peptide-based vaccines, one of several anti-tumor immunization strategies currently under investigation, can elicit both MHC Class I-restricted (CD8(+)) and Class II-restricted (CD4(+)) responses. However, the need to identify specific T-cell epitopes in the context of MHC alleles has hampered the application of this approach.
Saied, Mirshahidi +7 more
openaire +2 more sources
Biomolecules & Biomedicine, 2023 Colorectal cancer (CRC) is regarded as one of the most prevalent neoplasms worldwide, and ubiquitination and N6-methyladenosine (m6A) modification regulate the outgrowth of multiple cancers.
Juncai Li +8 more
doaj +1 more source
Internet-based profiler system as integrative framework to support translational research [PDF]
, 2005 Background Translational research requires taking basic science observations and developing them into clinically useful tests and therapeutics.
Alberto Riva +8 more
core +2 more sources
Scientific Reports, 2021 Prostate cancer (PCa) is dependent on the androgen receptor (AR). Advanced PCa is treated with an androgen deprivation therapy-based regimen; tumors develop resistance, although they typically remain AR-dependent.
Manjul Rana +4 more
doaj +1 more source
Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.Abstract INTRODUCTION Alzheimer's disease (AD) has been regarded as a brain‐first disorder. Emerging evidence suggests that the gut may influence central nervous system pathology, but the mechanisms remain unclear. METHODS We conducted a proteomic and microbial analysis of transverse colon samples from clinically and pathologically confirmed AD and ...
Qiwen Cheng +6 more
wiley +1 more source
Integration of copy number and transcriptomics provides risk stratification in prostate cancer : a discovery and validation cohort study [PDF]
, 2017 Study data are deposited in NCBI GEO (unique identifier number GSE70770).Background : Understanding the heterogeneous genotypes and phenotypes of prostate cancer is fundamental to improving the way we treat this disease.
Aho, Tevita +50 more
core +1 more source
Dropping in on the lipid droplet- tumor protein D52 (TPD52) as a new regulator and resident protein [PDF]
Adipocyte, 2016 Lipid droplets are essential for both the storage and retrieval of excess cellular nutrients, and their biology is regulated by a diverse range of cellular proteins, some of which function at the lipid droplet. Numerous studies have characterized lipid droplet proteomes in different organisms and cell types, and RNAi whole genome screening studies have
Yuyan, Chen +2 more
openaire +2 more sources
Neurons in a Dish: A Review of In Vitro Cell Models for Studying Neurogenesis
Journal of Neurochemistry, Volume 170, Issue 1, January 2026.Different in vitro cell models are valuable to study the different steps of neurogenesis, from the proliferation of neural stem and progenitor cells to the maturation of neurons. Pluripotent stem cells (including embryonic stem cells and induced pluripotent stem cells), immortalized human neuroblastoma cell lines (SH‐SY5Y, IMR‐32), and primary brain ...
Mariana Vassal +3 more
wiley +1 more source
Drug Design, Development and Therapy, 2021 Hui Zhang,1 Minghui Li,1 Jing Zhang,1 Yanbing Shen,2 Qi Gui2 1College of Medical, Huanghuai University, Zhumadian, Henan, People’s Republic of China; 2Department of Urology, The Central Hospital of Zhumadian, Zhumadian, Henan, People’s ...
Zhang H, Li M, Zhang J, Shen Y, Gui Q
doaj
TPD52L2 Is a Prognostic Biomarker and Correlated With Immune Infiltration in Lung Adenocarcinoma
Frontiers in Pharmacology, 2021 Tumor protein D52-like 2 (TPD52L2) belongs to the members of the TPD52 family. TPD52L2 was reported to regulate proliferation and apoptosis in cancer cells. However, its role in lung adenocarcinoma (LUAD) was uncertain.
Anyuan Zhong +4 more
doaj +1 more source