Results 61 to 70 of about 1,280 (139)
A case of chronic myelomonocytic leukemia complicated with immune thrombocytopenia [PDF]
Chronic myelomonocytic leukemia (CMML) complicated with immune thrombocytopenia (ITP) is rare. This article reports the clinical data of a patient with CMML complicated with ITP treated with a combination of venetoclax, ripertamab (an anti-CD20 ...
HAO Siguo, HUANG Fang, LIU Jiayu
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Huli yanjiu, 1991 黑索金是一种氧化剂,进入血液后,与血红蛋白作用,使正常的二价铁即可氧化成三价铁,而形成高铁血红蛋白,高铁血红蛋白能使正常红血蛋白失去携氧和释氧功能,造成各组织的缺氧,尤以中枢神经系统对缺氧更为敏感,从而产生了一系列的临床表现。 临床资料 一、一般情况 18例病人中,均来自化工厂工人,矿工及家属,其中男性8例,女性10例,年龄最大者62岁,最小者15岁,治愈17例（24小时内完全治愈者4例,三天内治愈者4例,6天内治愈8例）,死亡1例（入院抢救6小时死亡）,抢救成功率94％。
赵瑞萍, 刘钊
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Research progress on the regulation of signal pathways related to lung injury in sepsis by the active components of traditional Chinese medicine [PDF]
Sepsis is a systemic inflammatory response syndrome caused by infection，with resulting organ dysfunction being the key factor in mortality. The lung is one of the organs most frequently affected by sepsis. Recent studies have shown that active components
RONG Jilintai*，SU He，ZHANG Ruifen，ZHANG Hairong，JIA Tingting，GUO Sihan，ZHAO Jian，LI Xiao，ZHONG Xin
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SAS诱导氧化应激时人卵巢癌顺铂敏感细胞与耐药细胞死亡方式的差异
Zhongguo shiyan zhenduanxue, 2018 目的利用柳氮磺吡啶(Sulfalsalazine,SAS)诱导氧化应激,探讨卵巢癌非耐药细胞与耐药细胞死亡方式的差异。方法选用人卵巢癌顺铂敏感细胞SKOV3和顺铂耐药细胞SKOV3/DDP,实验分组为对照组(Con),SAS各剂量组。应用铁死亡抑制剂Fer-1,实验分组为对照组,SAS组,Fer-1组,Fer-1与SAS联合作用组。应用程序性坏死抑制剂Nec-1,实验分组为对照组,SAS组,Nec-1组,Nec-1与SAS联合作用组。MTT法检测细胞生存率,实时无标记细胞功能分析法(Real time ...
高玮男 +4 more
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Thalassemia Reports, 2011 Bone marrow transplantation (BMT) is the only possible curative treatment for β-thalassemia major. The largest experience occurred in Pesaro, Italy, where the BMT was applied after a standard risk assessment.
S.S. Anak
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MAPK4 Accelerates Progression of Cervical Squamous Cell Carcinoma by Positively Regulating SLC3A2 Expression [PDF]
ObjectiveTo explore the role of MAPK4 in cervical squamous cell carcinoma (CSCC) for the identification of candidate prognostic prediction biomarkers and molecular therapeutic targets.
Jing YU +4 more
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Progress of magnetic iron oxide nanoparticles in targeted diagnosis and treatment of pancreatic cancer [PDF]
Pancreatic cancer has a very poor prognosis. Early diagnosis and treatment are especially critical for improving its prognosis. Nanotechnology has been widely used in the diagnosis and treatment of pancreatic cancer. Relying on the unique physicochemical
REN Jiaqiang, WU Shuai, MO Jiantao, ZHOU Cancan, HAN Liang, WU Zheng
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Significant fundamental translational research on breast cancer in China: progress and prospects [PDF]
Breast cancer is the most prevalent malignant tumor that poses a threat to women's health in China, with incidence and mortality rates persistently increasing. Given this critical situation, there is an urgent need to optimize therapeutic options through
LU Yufeng, WANG Han, XIE Yifan, JIANG Yizhou, SHAO Zhimin
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Research progress in ceruloplasmin regulation of lipid metabolism homeostasis [PDF]
Ceruloplasmin (Cp) is a crucial protein secreted by the liver and plays a vital role in regulating the distribution and transport of copper throughout the body, thereby maintaining copper homeostasis.
CHEN Suzhen, JIANG Quanxin, LIU Junli
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Zhongshan Daxue xuebao. Yixue kexue ban血管性痴呆（VD）是一种由脑血管疾病造成的慢性进行性认知障碍，其发病机制复杂，主要包括神经细胞凋亡、氧化应激反应、炎症反应、铁死亡、线粒体损伤等因素导致的脑组织损伤。其中，氧化应激在VD发生发展中起关键作用，其可致自由基积累，破坏细胞结构，且与炎症反应、线粒体损伤、铁死亡、神经细胞凋亡密切相关，共同构成了一个复杂的致病网络，而中药单体在通过调控氧化应激治疗VD有显著效果。本文综述相关研究进展，探讨了氧化应激在VD中的作用机制，其通过Nrf2、LRP3、NF-κB等因子调控炎症反应 ...
陈信朝, 董新刚
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