Mechanism by Which Laser Irradiation Combined with Spirulina platensis Enhances FeSO4-Induced Ferroptosis in Salmonella Typhimurium and Listeria monocytogenes [PDF]
To explore the mechanism by which laser (L) irradiation combined with Spirulina platensis (SP) enhances ferroptosis induced by FeSO4 (Fe) in Salmonella enterica serovar Typhimurium (ST) and Listeria monocytogenes (LM), this study measured lipid ...
SUN Jinyue, PAN Jianeng, CHEN Yiying, LIU Rencheng, ZHOU Wenwen
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The role of ferroptosis suppressor protein 1 in tumors [PDF]
Ferroptosis suppressor protein 1 （FSP1） is a key suppressor in the process of ferroptosis， which can prevent cell death and has important biological functions and potential value in clinical application.
LI Hantong, LI Yuefan, ZHOU Yan, WANG Lin
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Research advances Progress in mechanistic studies of renal fibrosis based upon regulatory cell death [PDF]
As a basic pathological feature at advanced stage of various kidney diseases, renal fibrosis (RF) is an important cause of kidney failure. It is characterized by an excessive accumulation of extracellular matrix (ECM), damage of renal tissue structure ...
Guang-ming Yin +5 more
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Diagnosis of iron overload and heart disease by magnetic resonance imaging
Thalassemia Reports, 2011 The use of Magnetic resonance imaging (MRI) to estimate tissue iron was initiated nearly three decades ago but has only become a practical reality in the last ten years.
J.C. Wood, L. Noetzli
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Astaxanthin Reduces Retinal Damage in Diabetes Mice by Inhibiting Iron Death through Regulating Nrf2/Gpx4 Signaling Pathway [PDF]
Objective: To investigate the effect and mechanism of astaxanthin on retinal damage in diabetes mice. Methods: The mice were randomly divided into four groups: Normal group, model group, low-dose astaxanthin group and high-dose astaxanthin group. Retinal
Jia LIU +6 more
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Zhongguo shiyan zhenduanxue, 2023 目的 探究表没食子儿茶素没食子酸酯(EGCG)对阿霉素诱导下的心肌细胞铁死亡的影响及其保护机制。方法 体外培养大鼠H9C2心肌细胞，将H9C2心肌细胞分为4组：control组、DOX组、EGCG+DOX组、EGCG+DOX+ML385组进行对应的药物处理。DCFH-DA探针法检测活性氧(ROS);试剂盒检测线粒体膜电位(MMP)、丙二醛(MDA)、超氧化物歧化酶(SOD)、还原型谷胱甘肽(GSH)、铁离子(Fe2+);Western blot检测谷胱甘肽过氧化物酶4(GPX4)、核因子E2相关因子2 ...
左振岐, 刘春辉
doaj
Zhongguo shiyan zhenduanxue, 2019 2012年,Dixon等在探讨Erastin诱导RAS突变的肿瘤细胞发生死亡的作用机制时,发现了一种铁依赖的氧化损伤所引起的新型细胞死亡方式,命名为铁死亡[1],这种细胞死亡方式可能用于治疗肿瘤。野生型(wild-type,wt)p53是一种重要的抑癌基因,可以帮助细胞修复基因缺陷 ...
张佳悦 +5 more
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Inhibitory Effect and Mechanism of Procyanidin B2 on High Glucose-Induced Ferroptosis in SH-SY5Y Cells [PDF]
Objective: To investigate the neuroprotective effect and mechanism of procyanidin B2 on high glucose-induced ferroptosis in differentiated SH-SY5Y cells.
WANG Jiaqi, CHEN Xiuting, XIA Xing, ZHOU Jinling
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The inherited diseases of haemoglobin are an emerging global health burden
Thalassemia Reports, 2011 Thalasseamia is one of the common genetic disorders. A genetic defect causes reduction of the globin chains leading to chronic haemolytic anaemia from birth.
S. Fucharoen, P. Winichagoon
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Role of Ferroptosis-related Gene GLS2 in Pan-cancer Prognosis and Immunity [PDF]
Objective To assess the role of the ferroptosis-associated gene GLS2 in the prognosis of pan-cancer and immunity using bioinformatics methods. Methods GLS2 expression levels in pan-cancer were profiled using publicly available databases: The Cancer ...
HU Xuexue +4 more
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