Results 61 to 70 of about 1,248 (94)

FTL和FTH1在上皮性卵巢癌组织中的表达及意义

Zhongguo shiyan zhenduanxue
目的探讨铁蛋白重链（FTH1）、铁蛋白轻链（FTL）在上皮性卵巢癌组织中的表达情况及意义。方法免疫组织化学方法检测31例上皮性卵巢癌、11例良性卵巢肿瘤、25例正常卵巢组织中FTH1和FTL蛋白的表达情况。结果上皮性卵巢癌组中FTL表达水平高于良性卵巢肿瘤组和正常卵巢组，差异有统计学意义（P<0.05）；上皮性卵巢癌组中FTH1的表达水平高于正常卵巢组，差异有统计学意义（P<0.05）；Ⅲ~Ⅳ期上皮性卵巢癌中FTL和FTH1表达水平均高于Ⅰ~Ⅱ期上皮性卵巢癌，但差异无统计学意义（P>0.
张茸, 杨如琳, 裴越, 姜婉晴, 付莉   +4 more
doaj  

Ferroptosis and tumor immunity. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Tao Q, Liu N, Chen J, Wu J, Li J, Chen X, Peng C.   +6 more
europepmc   +1 more source

八味沉香丸激活磷脂酰肌醇3-激酶抑制铜死亡改善大鼠急性心肌缺血损伤

Zhongshan Daxue xuebao. Yixue kexue ban
目的为了研究藏药八味沉香丸（Bawei Chenxiang Wan，BCW）防治心肌缺血的有效活性部位及机制。方法建立异丙肾上腺素（isoproterenol，ISO）诱导大鼠在体心肌缺血模型、冠脉结扎离体心脏缺血模型，评估BCW全方、醇提物及其不同极性萃取物对心电图ST段、心肌损伤、血流动力学及心肌梗死的影响。检测心肌组织磷脂酰肌醇3-激酶（phosphatidylinositol 3-kinase，PI3K）磷酸化水平、铜死亡相关蛋白的表达，以及Cu²⁺含量。利用氧糖剥夺（oxygen ...
张晓英, 谢予荃, 张雨婵, 司祺, 肖元糊, 郭毓祺, 邵夏瑀   +6 more
doaj  

TAF1 aggravates ferroptosis by promoting the ubiquitin-mediated degradation of nuclear GPX4. [PDF]

J Zhejiang Univ Sci B
Ye K, Gan M, Sun L, Chen C, Lai X, He Y, Zhu M, Jiang W, Zhang H.   +8 more
europepmc   +1 more source

Ferroptosis and secondary nephrosis. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Zhang Y, Yang L.
europepmc   +1 more source

[Inhibition of ferroptosis by geniposide via activation of the SIRT3 signaling pathway to alleviate inflammatory injury in endothelial cells]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Sun WT, Zhao MM, Shi ZL.
europepmc   +1 more source

[Research Advances on the Autophagy and Ferroptosis 
in the Development and Treatment of Lung Cancer]. [PDF]

Zhongguo Fei Ai Za Zhi
Jiang C, Cui X, Zheng L, Deng C, Huang R, Hou B, Wang J.   +6 more
europepmc   +1 more source

[Fufang Changtai Decoction Inhibites Colorectal Cancer Through Ferroptosis: Investigation of the Underlying Mechanism]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Gu J, Li L, Liu M, Deng S, Yu J, Huo J, Ji Y.   +6 more
europepmc   +1 more source

基于TCGA数据库分析铁死亡代谢和lncRNA在结直肠癌中的表达及临床意义

Zhongguo shiyan zhenduanxue
结直肠癌是全世界范围内最为常见的消化道恶性肿瘤。近年来，结直肠癌发病率和死亡率均表现为逐年升高的趋势，严重威胁人类的身心健康，因为结直肠癌患者的早期临床症状较隐匿，多无明显症状，晚期则出现严重的症状，如贫血和体重减轻，多数患者自己察觉并至医院专业诊断时已至中晚期，到目前为止根治性的手术仍然是治疗结直肠癌的首选方案，但术后的高复发率、高转移率和低生存率等问题一直没有很好的解决，结直肠癌患者的预后仍然很差，因此寻找新的诊断和治疗方法是目前的首要任务[1-3]。
潘楠, 唐桂艳, 吕楠, 马太原
doaj  

[Protective effects of SESN2 on Erastin-induced ferroptosis in renal tubular cells and acute kidney injury]. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Song T, Liu M, Wan Q, Min J, Zhong Y, Gao H.   +5 more
europepmc   +1 more source