Results 71 to 80 of about 1,375 (156)

A preliminary study on the effect mechanism of a rice immune peptide in mice [PDF]

open access: yes
Objective: This study aimed to demonstrate the potential immunomodulatory activity in mice of rice immunopeptide GBP1 (NSVFRALPVDVVANAYR) screened previously.
HUANG Qingming   +6 more
core   +1 more source

CCR10通过NRF2抑制结直肠癌细胞铁死亡的机制研究

open access: yesZhongguo shiyan zhenduanxue
目的 探究C-C趋化因子受体10(C-C chemokine receptor 10,CCR10)在结直肠癌(colorectal cancer, CRC)中对细胞增殖和铁死亡的影响,并探究其影响铁死亡的机制。方法 在GEPIA数据库(Gene Expression Profiling Interactive Analysis)共表达分析CCR10与铁死亡关键基因的相关性。构建慢病毒介导的CCR10过表达(CCR10-OE)、敲除(CCR10-KO)及其阴性对照(NC)稳转HCT116细胞,采用细胞活力(
徐昰栋   +6 more
doaj  

A case of chronic myelomonocytic leukemia complicated with immune thrombocytopenia [PDF]

open access: yes
Chronic myelomonocytic leukemia (CMML) complicated with immune thrombocytopenia (ITP) is rare. This article reports the clinical data of a patient with CMML complicated with ITP treated with a combination of venetoclax, ripertamab (an anti-CD20 ...
HAO Siguo, HUANG Fang, LIU Jiayu
core   +1 more source

Progress on effects of BaP exposure on female reproductive system and pathogenic mechanisms [PDF]

open access: yes
Benzo[a]pyrene (BaP) is the most abundant environmental pollutant among polycyclic aromatic hydrocarbons (PAHs), and is widely distributed in air, water, soil, barbecue, and fried foods. Human beings are inevitably exposed to BaP. Studies have shown that
Qianqian GAO, Xiaoling FENG
core   +1 more source

SAS诱导氧化应激时人卵巢癌顺铂敏感细胞与耐药细胞死亡方式的差异

open access: yesZhongguo shiyan zhenduanxue, 2018
目的利用柳氮磺吡啶(Sulfalsalazine,SAS)诱导氧化应激,探讨卵巢癌非耐药细胞与耐药细胞死亡方式的差异。方法选用人卵巢癌顺铂敏感细胞SKOV3和顺铂耐药细胞SKOV3/DDP,实验分组为对照组(Con),SAS各剂量组。应用铁死亡抑制剂Fer-1,实验分组为对照组,SAS组,Fer-1组,Fer-1与SAS联合作用组。应用程序性坏死抑制剂Nec-1,实验分组为对照组,SAS组,Nec-1组,Nec-1与SAS联合作用组。MTT法检测细胞生存率,实时无标记细胞功能分析法(Real time ...
高玮男   +4 more
doaj  

Overview of the current issues and advances in haemopoietic stem cell transplantation for β-thalassemia major

open access: yesThalassemia Reports, 2011
Bone marrow transplantation (BMT) is the only possible curative treatment for β-thalassemia major. The largest experience occurred in Pesaro, Italy, where the BMT was applied after a standard risk assessment.
S.S. Anak
doaj   +1 more source

Research progress on the regulation of signal pathways related to lung injury in sepsis by the active components of traditional Chinese medicine [PDF]

open access: yes
Sepsis is a systemic inflammatory response syndrome caused by infection,with resulting organ dysfunction being the key factor in mortality. The lung is one of the organs most frequently affected by sepsis. Recent studies have shown that active components
RONG Jilintai*,SU He,ZHANG Ruifen,ZHANG Hairong,JIA Tingting,GUO Sihan,ZHAO Jian,LI Xiao,ZHONG Xin
core   +2 more sources

MAPK4 Accelerates Progression of Cervical Squamous Cell Carcinoma by Positively Regulating SLC3A2 Expression [PDF]

open access: yes
ObjectiveTo explore the role of MAPK4 in cervical squamous cell carcinoma (CSCC) for the identification of candidate prognostic prediction biomarkers and molecular therapeutic targets.
Jing YU   +4 more
core   +1 more source

Progress of magnetic iron oxide nanoparticles in targeted diagnosis and treatment of pancreatic cancer [PDF]

open access: yes
Pancreatic cancer has a very poor prognosis. Early diagnosis and treatment are especially critical for improving its prognosis. Nanotechnology has been widely used in the diagnosis and treatment of pancreatic cancer. Relying on the unique physicochemical
REN Jiaqiang, WU Shuai, MO Jiantao, ZHOU Cancan, HAN Liang, WU Zheng
core   +1 more source

Significant fundamental translational research on breast cancer in China: progress and prospects [PDF]

open access: yes
Breast cancer is the most prevalent malignant tumor that poses a threat to women's health in China, with incidence and mortality rates persistently increasing. Given this critical situation, there is an urgent need to optimize therapeutic options through
LU Yufeng, WANG Han, XIE Yifan, JIANG Yizhou, SHAO Zhimin
core   +1 more source

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