Results 21 to 30 of about 31,599 (213)
Policy Effectiveness in Managing Drug Shortages: Evidence From South Korea (2015–2024)
ABSTRACT Drug shortages represent a growing policy challenge for healthcare systems worldwide. This study investigates actual drug shortage events in South Korea from 2015 to 2024, using a “Shortage Occurred vs. Shortage Non‐Occurred” framework to distinguish real‐world disruptions from administrative classifications.
Seung‐Rae Yu
wiley +1 more source
Clinical significance of Twist, Bmi-1 and E-cadherin expression in Cervical Intraepithelial Neoplasia and Early Stage Cervical Cancer [PDF]
目的:研究Twist/Bmi-1/E-cadherin蛋白在早期宫颈癌组织、宫颈上皮内瘤变(CIN)组织与正常宫颈组织中的表达水平,探讨Twist/Bmi-1/E-cadherin在早期宫颈癌不同病变组织中表达的生物学意义,对宫颈癌患者预后的影响以及这三者之间的相关性。 方法:收集2009年7月—2013年10月在厦门大学附属中山医院手术切除的64例宫颈癌,41例CIN组织,12例正常宫颈组织石蜡标本,运用Elivision免疫组化法检测Twist/Bmi-1/E-cadherin在宫颈癌组织 ...
丁娅妮
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Multiple global change factors alter the scaling of nitrogen to phosphorus in alpine plants
Read the free Plain Language Summary for this article on the Journal blog. Abstract The stoichiometry and allometry of nitrogen (N) and phosphorus (P) reflect nutrient absorption and dynamic allocation by plants, and can be regulated by global change factors (e.g. nitrogen enrichment, climate warming and altered precipitation). Yet, how multiple global
Jiapu Li+10 more
wiley +1 more source
Study on the effects of down-regulating Annexin A3 expression on biological behaviors of lung adenocarcinoma and its molecular mechanism [PDF]
肺癌是我国第一大癌症,其发病率和死亡率均居恶性肿瘤之首,严重危害人类健康。肺癌按组织学类型可分为鳞癌、腺癌、小细胞癌和大细胞癌。近年来,肺腺癌(lungadenocarcinoma,AdC)的发病率呈逐步上升趋势,且患者死亡率高、预后极差。癌细胞易转移是肺腺癌患者预后差的主要原因,因此,探寻肺腺癌转移的分子机制及其新的治疗靶标,对于提高肺腺癌患者预后意义重大。我们前期研究中,采用定量蛋白质组学技术鉴定出AnnexinA3(Anxa3)为一个新的肺腺癌转移相关分子 ...
刘青青
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The pulmonary infection after tracheotomy is associated with poor prognosis of elderly patients with intracerebral hemorrhage. This paper summarized the influencing factors and preventive nursing measures of pulmonary infection after tracheotomy, in ...
ZHAO Yangshuang (赵杨爽)+2 more
doaj +1 more source
Long‐Term Time Horizons and Support for Public Investment
ABSTRACT Generating public support for long‐term public investment may require understanding what citizens perceive as the “long term” in politics and how these perceptions shape their preferences. Across two studies, we find that UK citizens generally understand “long term” as 5–10 years.
Matthew Barnfield+2 more
wiley +1 more source
The Analysis of Erlotinib on Brain Metastases in Patients with Non-small-cell Lung Cancer [PDF]
Background and objective Brain metastases are common in non-small-cell lung cancer (NSCLC) and the prognosis is poor. Erlotinib is a specific inhibitor of the epidermal growth factor receptor-associated tyrosine kinase (EGFRTKI), which has been gradually
Baohui HAN, Hao BAI
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目的 探讨前循环串联病变患者颈动脉支架置入后支架内再闭塞的可能影响因素及预后情况。 方法 回顾性连续收集2020年6月—2022年9月于临沂市人民医院就诊的前循环串联病变且术中接受颈动脉支架置入治疗患者的临床资料,并分析上述患者手术操作过程、血管再通、术后并发症以及预后情况。同时依据90 d功能预后,将患者分为预后良好组与预后不良组,采用多元logistic回归分析影响患者预后的独立危险因素。 结果 ...
王广英,张琰,于萍,刘基,赵振宇,王贤军,孙洪扬,宫健 (WANG Guangying, ZHANG Yan, YU Ping, LIU Ji, ZHAO Zhenyu, WANG Xianjun, SUN Hongyang, GONG Jian )
doaj +1 more source
Abstract Short‐term policy (STP) has attracted considerable attention as a form of time‐related public policy and is typically used to solve urgent problems. The objective of this study, which considers STP as policy myopia from an information science perspective, is to discuss the challenges encountered during the STP policymaking process and their ...
Prasongchai Setthasuravich+1 more
wiley +1 more source
Studies of cerebral venous circulation and coagulation function in patients with aneurysmal subarachnoid hemorrhage [PDF]
目的:1.利用全脑血管造影技术(DSA)和磁敏感加权成像(SWI)观察动脉瘤性蛛网膜下腔出血(aSAH)患者脑静脉循环的变化,并探讨其对患者病情的判断价值。 2.利用血栓弹力图(TEG)研究aSAH患者凝血功能的变化,旨为评估患者凝血及纤溶系统的改变提供新的思路。 方法:1.收集南京军区福州总医院57例aSAH患者、48例未破裂动脉瘤患者及45例非动脉瘤患者(正常对照组),利用DSA观察并比较三组患者脑微循环时间(mCCT)及脑静脉循环时间(vCCT)及脑微血管及皮质静脉的显影特征。 2 ...
李兵兵
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