Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Random Number Generation in Adults With Dyslexia: Further Evidence of Dyslexia-Related Executive Function Difficulties. [PDF]
Osofisan EJ, Carrus E, Smith-Spark JH.
europepmc +1 more source
Organ specificity of beta‐carotene induced lung gene‐expression changes in Bcmo1−/− mice
Yvonne G. J. van Helden +3 more
openalex +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
'The Hero's journey': Narratives on the transition to motherhood with cystic fibrosis. [PDF]
Haines AJ +3 more
europepmc +1 more source
A Supramolecular Enzyme Mimic That Catalyzes the 15,15′ Double Bond Scission of ,-Carotene [PDF]
Richard R. French +3 more
openalex +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Thinking Critically About Algorithms for Automated Detection of Behavior: 11 Guidelines for Social and Behavioral Scientists. [PDF]
de Barbaro K +2 more
europepmc +1 more source
Fourier transform infrared spectrum of the radical cation of β‐carotene photoinduced in photosystem II [PDF]
Takumi Noguchi +2 more
openalex +1 more source

