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Synthesis of some New 1,2,4-Triazole derivatives [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2013
In the present work, compound 3-arylidene amino-5-methyl-1,2,4-triazole (IIIa-c), required as starting material obtained in one-pot reaction by condensing 5-methyl-3-amino-1,2,4-triazole with different aromatic aldehydes.
Ibtehal Kahtan Abdullah
doaj   +2 more sources

Proton-Conducting Polymeric Membranes Based on 1,2,4-Triazole

open access: yesMembranes, 2023
In this review, a comparative analysis of the literature and our own results obtained in the study of the physicochemical, dielectric, and proton-conducting properties of composite polymer materials based on 1H-1,2,4-triazole has been carried out. It has
Galina F. Prozorova   +1 more
doaj   +3 more sources

1,2,4-Triazoles as Important Antibacterial Agents [PDF]

open access: yesPharmaceuticals, 2021
The global spread of drug resistance in bacteria requires new potent and safe antimicrobial agents. Compounds containing the 1,2,4-triazole ring in their structure are characterised by multidirectional biological activity. A large volume of research on triazole and their derivatives has been carried out, proving significant antibacterial activity of ...
Małgorzata Strzelecka, Piotr Świątek
openaire   +5 more sources

Synthesis and spectral characterization of 1,2,4-triazole derivatives [PDF]

open access: yesAIP Conference Proceedings, 2022
The authors G. Sravya and N. Bakkthavatchala Reddy are thankful to Ural Federal University, Yekaterinburg, Russia for financial assistance and thankful to Prof. A. Padmaja for providing necessary lab facility to carry out this research work.
Reddy, N. B.   +5 more
openaire   +3 more sources

Synthesis of Benzimidazole-1,2,4-triazole Derivatives as Potential Antifungal Agents Targeting 14α-Demethylase

open access: yesACS Omega, 2023
Invasive fungal infections (IFIs) are increasing as major infectious diseases around the world, and the limited efficacy of existing medications has resulted in substantial morbidity and death in patients due to the lack of effective antifungal agents ...
Emir Güzel   +7 more
semanticscholar   +1 more source

Design, synthesis and evaluation of novel 1,2,4-triazole derivatives as promising anticancer agents

open access: yesBMC Chemistry, 2022
Herein, we reported the synthesis of nineteen novel 1,2,4-triazole derivatives including 1,3-diphenyl-2-(1H-1,2,4-triazol-1-yl) propan-1-ones ( 7a-e ), 1-(1,3-diphenylpropan-2-yl)-1 H -1,2,4-triazole ( 8a-c ) and 1,4-diphenyl-2-(1H-1,2,4-triazol-1-yl ...
L. Emami   +8 more
semanticscholar   +1 more source

Modern approaches to studying the antimicrobial and antifungal activities of new 1,2,4-triazole derivatives

open access: yesФармацевтичний журнал, 2022
1,2,4-Triazole and its derivatives are a promising class of organic compounds. For a long time, they remain in the spotlight due to a number of unique properties: high ability to chemical transformations, the presence of various types of biological ...
M. V. Ogloblina   +2 more
doaj   +1 more source

Prospects for the search for new biologically active compounds among the derivatives of the heterocyclic system of 1,2,4-triazole.

open access: yesHacettepe university journal of the faculty of pharmacy, 2022
The authors are not native speakers of Turkish The purpose of this literature review was to systematize data from studies of the biological activity of 1,2,4-triazole derivatives with substituents in positions 4 and 5.
Yurii Sameliuk   +5 more
semanticscholar   +1 more source

Synthesis methods of 1,2,3-/1,2,4-triazoles: A review

open access: yesFrontiers in Chemistry, 2022
Triazole, comprising three nitrogen atoms and two carbon atoms, is divided into two isomers 1,2,3-triazole and 1,2,4-triazole. Compounds containing a triazole are one of the significant heterocycles that exhibit broad biological activities, such as antimicrobial, analgesic, anti-inflammatory, anticonvulsant, antineoplastic, antimalarial, antiviral ...
Jinlian Dai   +3 more
openaire   +3 more sources

3-Nitro-1H-1,2,4-triazole [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2010
تحتوي الوحدة غير المتماثلة لمركب العنوان، C(2)H(2)N(4)O(2)، على جزيئتين مستقلتين بلوريًا تكون فيهما حلقات التريازول مستوية بشكل أساسي، مع انحرافات قصوى قدرها 0.003 (1) Å في كلا الجزيئين. الزاوية الثنائية السطوح بين حلقتي 1H -1،2،4 - triazole هي 56.58 (5)درجة.
Madhukar Hemamalini, Hoong‐Kun Fun
openaire   +4 more sources

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