Results 21 to 30 of about 24,543 (214)
CHIMIA, 1981 With the addition of 1,2,4-triazole or imidazole to aqueous solutions 0.1 M in glycine and 0.1 M in trimetaphosphate at room temperature, pH range 6.7-8.9, the yield of triglycine is improved by a factor of 10 to 20; the best yields are obtained with 1 ...
J. Rabinowitz, A. Hampai
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Synthesis methods of 1,2,4-triazole-3-thiones: review
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki1,2,4-Triazole-containing compounds are unique heterocyclic compounds present in an array of pharmaceuticals and biologically important compounds used in drug-discovery studies against cancer cells, microbes, and various types of diseases in the human ...
Yu. S. Frolova +3 more
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Study acute toxicity of 4-(R-amino)-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol in vivo
Фармацевтичний журнал, 2018 Typically, the system is already known are used as the core for a new substance, which have already proved themselves as potential drugs. So one of these is 1,2,4-triazole ring.
A. A. Safonov
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Synthesis and Antimicrobial Activity of 1,2,4‐Triazoles [PDF]
Journal of Chemistry, 2004 Several 3‐(4′‐nitrophenyl)‐4‐(4"‐chloro benzamido)‐5‐substituted phenyl)‐4H‐1,2,4‐triazole (3a‐3e) and 3‐(4′‐nitrophenyl)‐4‐(4"‐methyl benzenesulphonamido)‐5‐substituted phenyl)‐4H‐1,2,4‐triazole (4a‐4e) have been synthesised. Representative compounds were screened for antibacterial, antifungal activity.
R. U. Roy, A. R. R. Desai, K. R. Desai
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Фармацевтичний журнал, 2018 The large interest in the plan of search biologically of active agents is caused by the heterocyclic system of 1,2,4-triazole, due to high biological activity, and by the low indexes of toxicness, that inherent it to the structural analogues.
Т. М. Kaplaushenko +2 more
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015 The amount of antibiotics has increased over the past decade. This also resulted in increase of microorganisms’ resistance to this class of drugs. Therefore, the synthesis of new compounds that have exhibited antimicrobial and antifungal activity and low
O. A. Suhak +3 more
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Synthesis and Characterization of the Triazole Derived from Thiosemicarbazide, 4-Amino-5-Phenyl-4H-1,2,4- Triazole-3-Thiol and Their Copper(II) and Nickel(II) Complexes [PDF]
Engineering and Technology Journal, 2013 Triazole N-(3-mercapto-5-phenyl-4H-1,2,4-triazol-4-yl)hydrazinecarbothioamide prepared in good yield via the condensation of 4-amino-5-phenyl-4H-1,2,4-triazole-3-thiol and thiosemicarbazide.
Hamdan Abood Aday
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An insight on medicinal attributes of 1,2,4-triazoles
European Journal of Medicinal Chemistry, 2020 The present review aims to summarize the pharmacological profile of 1,2,4-triazole, one of the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant, antituberculosis, antiviral, antiparasitic, analgesic and anti-inflammatory agents, etc. along with structure-activity relationship.
Ranjana Aggarwal, Garima Sumran
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Tandem transformations of 1,2,4-triazol-5-ylidenes into 5-amidino-1,2,4-triazoles [PDF]
Arkivoc, 2007 The first tandem autotransformations of heteroaromatic carbenes have been found. These reactions involve cleavage of the 1-tert-butyl-3,4-diaryl-1,2,4-triazol-5-ylidenes 1a-d to form benzonitriles and the respective carbodiimides, followed by further reactions of the latter with carbenes 1a-d to afford the 3,4-diaryl-5-(1-tert-butyl-3-arylamidin-2-yl ...
Korotkikh, Nikolai I. +6 more
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Energies, 2019 N,N,N′,N′-Tetramethylethylenediamine (TMEDA) is one of the candidate substances of hydrazine for hypergolic bipropellant applications. In this study, two experimental analyses were performed to investigate the characteristics of TMEDA and ...
Jungmin Yu +2 more
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