Molecular docking, microwave-assisted synthesis, characterization, and preliminary evaluation of the anti-microbial activity of new sulfonamide derivatives of the 1, 2, 4-triazole-3-thiol ring system [PDF]
A new sulfonamide derivative containing a 1,2,4-Triazole-3-thiol ring was synthesized and characterized using FT-IR and 1H-NMR. The microwave-assisted chemical synthesis of the 1,2,4-Triazole-3-thiol ring system resulted in good yield and purity.
Ali Abdulhadi Mosleh, Zainab A. Dakhel
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Anti-Tubercular Properties of 4-Amino-5-(4-Fluoro-3- Phenoxyphenyl)-4H-1,2,4-Triazole-3-Thiol and Its Schiff Bases: Computational Input and Molecular Dynamics. [PDF]
Antibiotics (Basel), 2020 Venugopala KN +6 more
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Synthesis and Antibacterial Activity of some 5,5’-(1,4-phenylene)-bis-1,3,4-Oxadiazole and bis-1,2,4-Triazole Derivatives as Precursors of New S-Nucleosides [PDF]
, 2015 Five compounds, namely 5,5’-benzene-1,4-diylbis(1,3,4-oxadiazole-2-thiol)6 and 5,5’-benzene-1,4-diylbis(1H-1,2,4-triazole-3-thiol) 7a and its derivatives 7b–d were synthesized. Two related S-nucleosides 9 and 10 have been prepared from 6 and 7a.
Datoussaid, Y, Kirsch, G, Othman, A
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In silico study, Synthesis, Characterization and Preliminary Evaluation of Antimicrobial activity of new sulfonamide – 1,2,4-triazole derivatives [PDF]
A new series of sulfonamide derivatives (6a-c), containing 1,2,4-triazole-3-thiol (5a-c) ring system, were synthesized and their structures were identified by using ATR-FT-IR and 1HNMR spectroscopic analytical techniques.
Ali. Abdulhadi. Mosleh +1 more
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Design, synthesis and evaluation of antifungal activity of novel triazole-3-thiol derivatives containing substituted phenyl moiety as inhibitors of enolase 1 [PDF]
The emergence of azole resistant candida species is a significant clinical problem and indicates an urgent need for novel medications and treatment approaches.
Beegum, Fathima +7 more
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Synthesis, characterization and anti-microbial screening of novel heterocyclic system containing bridgehead nitrogen atom [PDF]
, 2020 The nicotino hydrazide (1) on reaction with carbon disulphide and ethanolic potassium hydroxide followed by treatment with hydrazine hydrate give 4-amino-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol (3).
G Omprakash +5 more
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Synthesis, Structural Analysis and Thermal Behavior of New 1,2,4-Triazole Derivative and Its Transition Metal Complexes [PDF]
, 2022 AL Majidi, Mohammed Idaan Hassan +6 more
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Synthesis, invitro and invivo anti-hyperglycemic activity of 1,2,4-triazolebenzylidene and 1,3,4-thiadiazole derivatives [PDF]
, 2020 : New series of 1,2,4-triazole based Schiff base (5a-5i) and 1,3,4-thiadiazole (6a-6g) derivatives were synthesized by utilizing 4-amino-5-(4-chloro-2-methylphenyl)-4H-1,2,4-triazole-3-thiol (4) as active intermediateand evaluated for invitro anti ...
Arun Sindhe +6 more
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta PraktikiMost pharmaceutical compounds interact with various molecular compositions in the body, leading to complex biological effects. Furthermore, during biotransformation, they may generate one or more metabolites with potent bioactive properties.
Yu. V. Karpenko +2 more
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