Results 91 to 100 of about 13,327,440 (231)

Small-molecule APOBEC3G DNA cytosine deaminase inhibitors based on a 4-amino-1,2,4-triazole-3-thiol scaffold. [PDF]

ChemMedChem, 2013
APOBEC3G (A3G) is a single‐stranded DNA cytosine deaminase that functions in innate immunity against retroviruses and retrotransposons. Although A3G can potently restrict Vif‐deficient HIV‐1 replication by catalyzing excessive levels of G→A hypermutation,
Olson ME, Li M, Harris RS, Harki DA.
europepmc   +2 more sources

Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds

ChemMedChem, Volume 21, Issue 2, January 2026.
Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley   +1 more source

Computational and Experimental Analyses of the Synergistic Corrosion Inhibition of Green Phytochemicals Found in Yellow Bush in Acidic Media

Engineering Reports, Volume 8, Issue 1, January 2026.
Synergistic interaction was observed to exist between terpineol, 1,5,9‐undecatriene‐2,6,10‐trimethyl‐(Z), and hexadecanoic acid‐methyl ester present in yellow bush. Yellow bush (YB) reduced acidic corrosion of API 5 L X65 steel, achieving optimum inhibition efficiency (IE) of 77.53% at 40 ppm, 89.99 at 60 ppm from WL, EIS and Tafel plots.
Joseph Itodo Emmanuel, Fayen Odette Ngasoh, Chidiebele E. J. Uzoagba, Abdulhakeem Bello, Vitalis Chioh Anye, Azikiwe Peter Onwualu, Baboo Yashwansingh Surnam, Okoye Cyril Onyeka   +7 more
wiley   +1 more source

Features of the vegetative state and arterial pressure level in children with chronic gastroduodenal pathology

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
Introduction. Heterocyclic compounds are the foundation on which the creation of medicines is successfully carried out. One such system is 1,2,4-triazole and 3-methylxanthine.
A. S. Hotsulia
doaj   +1 more source

Precision‐Engineered Poly(GMA‐EGDMA) Microspheres for Multifunctional Applications

Particle &Particle Systems Characterization, Volume 43, Issue 1, January 2026.
The study presents multifunctional poly(GMA‐EGDMA) microspheres designed for advanced separation, catalysis, and biomedical engineering. Through precision synthesis and surface engineering, these microspheres exhibit excellent stability, tunable porosity, and high reactivity.
Imran Ali, Shakeel Ahmad Khan, Mujeeb ur Rahman, Abdul Wasy Zia   +3 more
wiley   +1 more source

Molecular docking, microwave-assisted synthesis, characterization, and preliminary evaluation of the anti-microbial activity of new sulfonamide derivatives of the 1, 2, 4-triazole-3-thiol ring system

Pharmacia
A new sulfonamide derivative containing a 1,2,4-Triazole-3-thiol ring was synthesized and characterized using FT-IR and 1H-NMR. The microwave-assisted chemical synthesis of the 1,2,4-Triazole-3-thiol ring system resulted in good yield and purity.
Ali. Abdulhadi. Mosleh, Z. Dakhel
semanticscholar   +1 more source

A New Class of Benzo[b]Thiophene‐1,3,4‐Oxadizole Bearing 1,2,4‐Oxadiazoles as Potent Antimicrobial Targets: Synthesis, Biological Evaluation, Docking, DFT and ADMET Studies

ChemistrySelect, Volume 11, Issue 3, 22 January 2026.
Benzo[b]thiophene‐1,3,4‐oxadizole and 1,2,4‐oxadiazole hybrids 9a–9l were tested against both antibacterial and anticancer, revealing interesting structure‐activity relationships. density functional theory calculations (DFTs) at the B3LYP/6–311++G (d,p).
Ravikumar Gupta Miriyala, Janardan Sannapaneni, Phani Raja Kanuparthy, Venkata Ramana Singamaneni, Tejeswara Rao Allaka, Pilli Veera Venkata Nanda Kishore   +5 more
wiley   +1 more source

Synthesis and structure of novel 1,2,4-triazole derivatives containing the 2,4-dinitrophenylthio group [PDF]

, 2009
Some novel 1,2,4-triazole derivatives containing the 2,4-dinitrophenylthio group have been synthesised in high yields by means of the reactions of 3-substituted-4-amino -1H-1,2,4-triazole-5(4H)-thiones or (E)-3-aryl-4-(benzylideneamino)-1H-1,2,4-triazole-
Du, HA, Ding, JY, Zhang, LX, Ding, QC, Zhang, LX, Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325027, Peoples R China., Lei, XX, Zhang, HL   +6 more
core  

Electrochemical and Theoretical Investigation of Triazole Derivatives as Corrosion Inhibitors for Copper in 3.5% NaCl Solution

International Journal of Electrochemical Science, 2013
This paper presents the investigation of 4-amino-5-phenyl-4H-1,2,4- triazole-3-thiol and 4-amino-5-nitrophenyl-4H-1,2,4-triazole-3-thiol as corrosion inhibitors for copper in 3.5% NaCl solution. Determinations of weight loss, electrochemical measurements,
Huiwen Tian, Weihua Li, Baorong Hou
doaj   +1 more source

The synthesis of 3-methyl-6-R-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives

Журнал органічної та фармацевтичної хімії, 2020
Aim. To conduct the synthesis and confirm the structure of 3-methyl-6-R-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives as potential biologically active compounds. Results and discussion. It has been shown that the heterocyclization reaction of 4-
Tetiana V. Hlazunova, Olexandr I. Panasenko, Yevhen G. Knysh   +2 more
doaj   +1 more source