Results 81 to 90 of about 13,327,440 (231)

Modern approaches to the synthesis and biological screening of 1,2,4-triazole-3-thiol derivatives (literature review)

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
Aim. To systematize and critically analyze current scientific publications on the synthesis and biological screening of 1,2,4-triazole-3-thiol derivatives and to summarize the relationship between their structure and pharmacological activity.
V. V. Kalchenko , R. O. Shcherbyna
doaj   +1 more source

FUSED 1,2,4-TRIAZOLE HETEROCYCLES. II: REACTION OF 2-CHLORO-3-(1,3-DIOXOLAN- 2-YL)QUINOLINES WITH 1,2,4-TRIAZOLE-5THIOL [PDF]

, 1995
Reaction of 2-chloro-3-(1,3-dioxolan-2-yl)quinolines 1 with 1,2,4-triazole-5-thiol 2 leads to the formation of a mixture of 11-(2-hydroxyethyl)oxy-11H-[1,2,4]triazolo[5',1':2,3][1,3]thiazino[6,5-b]quinolines 3 and 11-(2-hydroxyethyl)oxy-11/-/-[1,2,4 ...
Szabó, Zoltan,, Cziaky, Z., Ferenc Kóródi, Zoltán Szabo, Zoltán Cziaky, Kćrćdi, F.   +5 more
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Design, synthesis and molecular docking of novel triazole derivatives as potential CoV helicase inhibitors

Acta Pharmaceutica, 2020
Middle East respiratory syndrome coronavirus (MERS-CoV) had emerged and spread because of the worldwide travel and inefficient healthcare provided for the infected patients in several countries.
Zaher Nashwa Hafez, Mostafa Mohammed Ismail, Altaher Abdullah Yousef   +2 more
doaj   +1 more source

Recent Advances in Bioconjugation of Aromatic Amino Acid Residues by a Reactivity‐Guided Approach

The Chemical Record, Volume 26, Issue 2, February 2026.
This review highlights recent advances in the bioconjugation of aromatic amino acids residues, focusing on strategies that leverage their inherent chemical reactivity to enable precise and versatile modifications of biomacromolecules, illustrating relevant applications.
Bruno M. da S. Santos, Lívia C. R. M. da Frota, Thais G. Silva, Fernanda G. Finelli   +3 more
wiley   +1 more source

Mesoionische N‐Heterocyclische Olefine, Imine, Thione, Phosphinidene und ihre Anwendung in der Katalyse

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
Dieser Mini‐Review behandelt die neuesten Fortschritte bei der Synthese, Reaktivität und metallfreien katalytischen Verwendung von mesoionischen N‐heterocyclischen Olefinen (mNHOs), Iminen (mNHIs), Thionen (mNHTs) und Phosphinidenen (mNHPs). Kurzzusammenfassung Übergangsmetallverbindungen sind allgemein für ihre Fähigkeit bekannt, kleine Moleküle zu ...
Subir Maji, Sreejyothi P., Max M. Hansmann, Swadhin K. Mandal   +3 more
wiley   +1 more source

Mesoionic N‐Heterocyclic Olefins, Imines, Thiones, Phosphinidenes and Their Application in Catalysis

Angewandte Chemie International Edition, Volume 65, Issue 3, 16 January 2026.
This minireview covers recent advances in the synthesis, reactivity, and metal‐free catalytic uses of mesoionic N‐heterocyclic olefins (mNHOs), imines (mNHIs), thiones (mNHTs), and phosphinidenes (mNHPs). Abstract Transition metal compounds are widely known for their ability to activate small molecules and are excellent catalysts for a wide range of ...
Subir Maji, Sreejyothi P, Max M. Hansmann, Swadhin K. Mandal   +3 more
wiley   +1 more source

Synthesis of some novel Schiff bases containing 1,2,4-triazole ring [PDF]

, 2010
4-Allyl-5-piridine-4-yl-4H-1,2,4-triazole-3-thiol was prepared under facile condition via the formation of 2-isonicotinoyl-N-allylhydrazinecarbothioamide. In addition, ethyl[(4-allyl-5-pyridine-4-yl-4H-1¸2¸4-triazole-3-yl)thio]acetate was synthesized via
Foroughifar, Naser, Mobinikhaledi, Akbar, Khanpour, Mansooreh, Ebrahimi, Sattar   +3 more
core   +1 more source

Investigation of diuretic activity of 4-R-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazoles’ derivatives

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
It should be noted, that the clinical and therapeutic effect of diuretic drugs is not necessarily associated with an increase diuresis. So, for example, diuretics are also prescribed as a means of dehydration emergency therapy for pulmonary edema, brain,
O. A. Suhak, O. I. Panasenko, Ye. G. Knysh, A. A. Safonov   +3 more
doaj   +1 more source

The Chemistry of Subphthalocyanines: Synthetic Strategies for their Axial, Peripheral, and Remote Postfunctionalization

ChemistryEurope, Volume 4, Issue 1, January 2026.
From axial and peripheral reactivity to remote derivatization, the chemical versatility of subphthalocyanines (SubPcs) renders them ideal scaffolds for the design of advanced functional materials. This review assembles the synthetic toolbox, key reaction conditions, and future challenges in SubPc functionalization, guiding the development of next ...
Marta Gómez‐Gómez, Juan Laforga‐Martín, Jorge Labrador‐Santiago, Jorge Labella, Tomás Torres   +4 more
wiley   +1 more source

Síntese e caracterização de novos materiais funcionais contendo 1,2,4-oxadiazol, 1,3,4-oxadiazol e 1,2,3-triazol [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2014Neste trabalho de tese de doutorado são apresentadas as sínteses ecaracterizações de três novas ...
Girotto, Edivandro
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