Results 71 to 80 of about 14,929 (209)
SYNTHESIS AND BIOACTIVITY OF 5,5'-BUTANE-BIS-4-SUBSTITUTED-4H-1,2,4-TRIAZOLE-3-THIOLS)
Scientific Bulletin of the Uzhhorod University. Series «Chemistry», 2020 Похідні 1,2,4-триазолу володіють рядом цінних фармакологічних властивостей і застосовується у медицині, сільському господарстві, фотосправі. Водночас, відомості про похідні біс-триазолу обмежені. Зокрема відомий метод синтезу основ Манніха – похідних 5,5'-бутан-біс-1,2,4-триазол-3-тіонів, деякі з яких проявляють антиоксидантну, антифунгіцидну та ...
Korol, N. I. +5 more
openaire +3 more sources
Design, Synthesis and Molecular Modeling Studies of Triazole Derivatives as Aromatase İnhibitors
Chemical Biology &Drug Design, Volume 107, Issue 5, May 2026.In this study, a new series of 1,3,4‐triazole derivative compounds was designed and synthesized. The cytotoxicity of these synthesized compounds on the breast cancer cell line MCF‐7 was determined by the MTT method. The enzyme inhibition potentials of compounds 3ı, 3g, 3n, and 3m, which are effective on both MCF‐7 and the aromatase enzyme, were ...
Emine Rana Bağcı +5 more
wiley +1 more source
Investigation of diuretic activity of 4-R-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazoles’ derivatives
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018 It should be noted, that the clinical and therapeutic effect of diuretic drugs is not necessarily associated with an increase diuresis. So, for example, diuretics are also prescribed as a means of dehydration emergency therapy for pulmonary edema, brain,
O. A. Suhak +3 more
doaj +1 more source
Organic and Metallacages for Chemical Sensing: Progress in Water‐Compatible Systems
Advanced Sensor Research, Volume 5, Issue 3, March 2026.Supramolecular cages function as three‐dimensional receptors for selective molecular recognition and sensing, and this review outlines design principles for water‐stable architectures, key analyte‐ and medium‐dependent challenges, recent water‐compatible examples (including polymer‐integrated systems), and future opportunities for cage‐based ...
Rabia Zahid +4 more
wiley +1 more source
f‐Block Element‐Based MOF Thin Films: A Platform for Luminescence, Sensing, and Energy Applications
Small, Volume 22, Issue 16, 17 March 2026.f‐Block element–based metal–organic framework (f‐MOF) thin films offer exceptional potential for luminescent, sensing, and energy‐related applications. This review surveys recent progress in their synthesis, characterization, and functional implementation, emphasizing the diversity of available thin‐film fabrication strategies. The convergence of these
Dong‐Hui Chen, Christof Wöll
wiley +1 more source
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018 Introduction. Heterocyclic compounds are the foundation on which the creation of medicines is successfully carried out. One such system is 1,2,4-triazole and 3-methylxanthine.
A. S. Hotsulia
doaj +1 more source
Recent Advances in Bioconjugation of Aromatic Amino Acid Residues by a Reactivity‐Guided Approach
The Chemical Record, Volume 26, Issue 2, February 2026.This review highlights recent advances in the bioconjugation of aromatic amino acids residues, focusing on strategies that leverage their inherent chemical reactivity to enable precise and versatile modifications of biomacromolecules, illustrating relevant applications.
Bruno M. da S. Santos +3 more
wiley +1 more source
Discussion of antimicrobial and antifungal activity of 4-amino-5-methyl-4H-1,2,4-triazole-3-thiol
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017 Studying new biologically active substances nowadays become increasingly important. The current range of the pharmaceutical market requires constant updating of domestic products.
T. V. Kravchenko +2 more
doaj +1 more source
Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.Dieser Mini‐Review behandelt die neuesten Fortschritte bei der Synthese, Reaktivität und metallfreien katalytischen Verwendung von mesoionischen N‐heterocyclischen Olefinen (mNHOs), Iminen (mNHIs), Thionen (mNHTs) und Phosphinidenen (mNHPs). Kurzzusammenfassung Übergangsmetallverbindungen sind allgemein für ihre Fähigkeit bekannt, kleine Moleküle zu ...
Subir Maji +3 more
wiley +1 more source
PharmaciaA new sulfonamide derivative containing a 1,2,4-Triazole-3-thiol ring was synthesized and characterized using FT-IR and 1H-NMR. The microwave-assisted chemical synthesis of the 1,2,4-Triazole-3-thiol ring system resulted in good yield and purity.
Ali. Abdulhadi. Mosleh, Z. Dakhel
semanticscholar +1 more source