Results 71 to 80 of about 13,327,440 (231)

Synthesis and acute toxicity of new S-derivatives (1,2,4-triazole-3(2H)-yl)methyl) thiopyrimidines

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2023
In the literature, there is insufficient information on the synthesis of compounds in a series of pyrimidine-2-thiol derivatives containing a five-membered nitrogen-containing heterocyclic fragment; at the same time, there are a sufficient number of ...
Yu. V. Karpenko, O. I. Panasenko, S. M. Kulish, A. V. Domnich   +3 more
doaj   +1 more source

Design, Synthesis and Molecular Modeling Studies of Triazole Derivatives as Aromatase İnhibitors

Chemical Biology &Drug Design, Volume 107, Issue 5, May 2026.
In this study, a new series of 1,3,4‐triazole derivative compounds was designed and synthesized. The cytotoxicity of these synthesized compounds on the breast cancer cell line MCF‐7 was determined by the MTT method. The enzyme inhibition potentials of compounds 3ı, 3g, 3n, and 3m, which are effective on both MCF‐7 and the aromatase enzyme, were ...
Emine Rana Bağcı, Hayrani Eren Bostancı, Şennur Görgülü, Merve Yıldırım, İsmail Çelik, Ulviye Acar Çevik   +5 more
wiley   +1 more source

New Insights into 1,2,4-Triazole-3-Thiol Chemistry: Synthesis and Tuberculostatic Activity

International Journal of Environmental Sciences
Background: Tuberculosis (TB), a formidable global health crisis, relentlessly claims countless lives annually, perpetuating widespread morbidity and mortality. The dire need for groundbreaking treatments has ignited fervent research into innovative therapeutic paradigms. Materials and Methods: This pioneering study embarked on synthesizing an array of
Pooja Koganole, Pooja Gouda, Sushmita Hiremath, Sagar Shiraguppi, Suresh Honnalli, Pradeepkumar M. Ronad, Sanket Hosamani   +6 more
openaire   +1 more source

1,2,4-Triazole-3-thiol-protected silver-nanoparticles as a platform for ECE electrochemical reaction

Electrochemistry Communications, 2017
Abstract Incorporation of “green chemistry” principles into nanotechnology has become one of the key subjects for nanoscience researches. In this work, we report an electrochemical reaction with ECE mechanism on the surface of 1,2,4-triazole-3-thiol-protected silver nanoparticles (TATAgNPs) via electrochemical oxidation of catechol in the presence ...
Hamid Salehzadeh, Davood Nematollahi, Ali Hajian   +2 more
openaire   +1 more source

Synthesis and physical properties of esters of 2-[5-((theophylline-7ʹ-yl)methyl)-4-R-1,2,4-triazole-3-ylthio]acetic acid

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
The large synthetic potential and high biological potential in the series of 1,2,4-triazole derivatives cause favorable conditions for the search for new biologically active substances.
A. S. Gotsulya
doaj   +1 more source

Organic and Metallacages for Chemical Sensing: Progress in Water‐Compatible Systems

Advanced Sensor Research, Volume 5, Issue 3, March 2026.
Supramolecular cages function as three‐dimensional receptors for selective molecular recognition and sensing, and this review outlines design principles for water‐stable architectures, key analyte‐ and medium‐dependent challenges, recent water‐compatible examples (including polymer‐integrated systems), and future opportunities for cage‐based ...
Rabia Zahid, Martina Viola, Maria Vittoria Balli, Guillermo Moreno‐Alcántar, Pierre Picchetti   +4 more
wiley   +1 more source

Electrochemical behaviour of 5-benzyl-4-( 4' -methylphenyl)-4H-1,2,4- triazole-3-thiol by voltammetry

, 2007
Canakkale Onsekiz Mart University, Science and Arts Faculty, Department of Chemistry, 17100 Canakkale/Turkey E-mail: ydilgin@comu.edu.tr, ydilgin@yahoo.com Fax: 90-2862-180533 Department of Chemistry, Faculty of Arts and Sciences, Firat University, 23119 Elazig/Turkey Ege University, Science Faculty, Department of Chemistry, 35100 Bornova-lzmir/Turkey ...
Dilgin Y., Koparir M., Çetin A., Cansiz A., Yilmaz S., Giray D.   +5 more
openaire   +5 more sources

SYNTHESIS AND BIOACTIVITY OF 5,5'-BUTANE-BIS-4-SUBSTITUTED-4H-1,2,4-TRIAZOLE-3-THIOLS)

Scientific Bulletin of the Uzhhorod University. Series «Chemistry», 2020
Похідні 1,2,4-триазолу володіють рядом цінних фармакологічних властивостей і застосовується у медицині, сільському господарстві, фотосправі. Водночас, відомості про похідні біс-триазолу обмежені. Зокрема відомий метод синтезу основ Манніха – похідних 5,5'-бутан-біс-1,2,4-триазол-3-тіонів, деякі з яких проявляють антиоксидантну, антифунгіцидну та ...
Korol, N. I., Holovko-Kamoshenkova, O. M., Slivka, M. V., Pallah, O. V., Boyko, N. V., Lendel, V. G.   +5 more
openaire   +3 more sources

f‐Block Element‐Based MOF Thin Films: A Platform for Luminescence, Sensing, and Energy Applications

Small, Volume 22, Issue 16, 17 March 2026.
f‐Block element–based metal–organic framework (f‐MOF) thin films offer exceptional potential for luminescent, sensing, and energy‐related applications. This review surveys recent progress in their synthesis, characterization, and functional implementation, emphasizing the diversity of available thin‐film fabrication strategies. The convergence of these
Dong‐Hui Chen, Christof Wöll
wiley   +1 more source

Three-component reaction between ethyl carbazate, potassium selenocyanate and aroyl chlorides: Synthesis of 1,2,4-triazole-3-selones [PDF]

, 2022
We reported a three-component, simple, one-pot, and novel method for the synthesis of 1,2,4-triazole-3-selones from the condensation of potassium selenocyanate and aroyl chlorides with ethyl carbazate at room temperature.
Mohsen Mohammadi (5593175), Razieh Mohebat (3348872), Mohammad H. Mosslemin (7479770), Alireza Hassanabadi (586732)   +3 more
core   +1 more source