Results 171 to 180 of about 2,851 (224)

X-ray structural insights and computational analysis of the compound 5-ethyl-4-[(4-morpholino-benzylidene)amino]-2,4-di-hydro-3<i>H</i>-1,2,4-triazole-3-thione. [PDF]

Acta Crystallogr E Crystallogr Commun
Nizamuddin S, Prasad TNM, Sreenatha NR, Sharath CL, Lakshminarayana BN, Vishnumurthy KA.   +5 more
europepmc   +1 more source

Triazole-imidazo[1,2-<i>b</i>]pyrazoles Able to Counteract Melanoma Cell Survival Without Compromising the Viability of Healthy Keratinocytes. [PDF]

Int J Mol Sci
Brullo C, Marengo B, Domenicotti C, Lusardi M, Cichero E, Salis A, Caviglia D, Russo E, Spallarossa A.   +8 more
europepmc   +1 more source

7-Methoxybenzofuran-triazole tethered <i>N</i>-phenylacetamides as a promising class of tyrosinase inhibitors: synthesis, biological evaluation and computational analyses against fungal and human tyrosinases. [PDF]

RSC Adv
Mushtaq A, Zahoor AF, Kamal S, Mojzych M, Saif MJ, Bhat MA.   +5 more
europepmc   +1 more source

Bivalent transition metal complexes of triazole pyridine Schiff base with theoretical and biological investigations. [PDF]

Sci Rep
Mannaa AH, Gomaa EA, Zaky RR, Ghaith EA, Abd El-Hady MN.   +4 more
europepmc   +1 more source

New 1,2,4-Triazole Derivatives with a <i>N</i>-Mannich Base Structure Based on a 4,6-Dimethylpyridine Scaffold as Anticancer Agents: Design, Synthesis, Biological Evaluation, and Molecular Modeling. [PDF]

Int J Mol Sci
Świątek P, Glomb T, Wiatrak B, Nowotarska P, Gębarowski T, Wojtkowiak K, Jezierska A, Strzelecka M.   +7 more
europepmc   +1 more source

Elucidating structural and molecular requirements of somatostatin subtype-4 agonist bound complexes using quantum mechanics approaches.

Org Biomol Chem
Slater O, Kontoyianni M.
europepmc   +1 more source

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Alkylation of 1,2,4-triazole-3-thiols with haloalkanoic acid esters

Russian Journal of Organic Chemistry, 2017
Alkylation of 4,5-disubstituted 4H-1,2,4-triazole-3-thiols with methyl chloroformate and ethyl chloroacetate chemoselectively afforded the corresponding S-alkyl derivatives, whereas the alkylation of 5-benzyl-4-phenyl-4H-1,2,4-triazole-3-thiol with methyl 3-bromopropanoate gave an inseparable mixture of S- and N-alkylation products. Hydrazinolysis of S-
M. A. Samvelyan, T. V. Ghochikyan, S. V. Grigoryan, R. A. Tamazyan, A. G. Aivazyan   +4 more
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Synthesis of 1,2,4-triazole-3-thiols and their S-substituted derivatives

Russian Journal of Organic Chemistry, 2010
New 1,2,4-triazole-3-thiols were synthesized by reactions of the corresponding carboxylic acid hydrazides with isothiocyanates and subsequent cyclization of intermediate 1,4-substituted thiosemicarbazides. Alkylation of 1,2,4-triazole-3-thiols with benzyl chlorides and bromacetophenones gave only S-substituted derivatives.
T. V. Kochikyan, M. A. Samvelyan, V. S. Arutyunyan, A. A. Avetisyan, R. A. Tamazyan, A. G. Aivazyan   +5 more
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Oxidation of 4-amino-5-aryl-4H-1,2,4-triazole-3-thiols

Russian Journal of Organic Chemistry, 2011
A simple and efficient method for the preparation of triazolesulfonic acids (II) is presented.
A. A. Shklyarenko, A. V. Moskvin, E. V. Fedorova   +2 more
openaire   +1 more source

Synthesis and antimicrobial activity of new 1,2,4-triazole-3-thiol metronidazole derivatives

Monatshefte für Chemie - Chemical Monthly, 2010
New 1,2,4-triazole-3-thiol metronidazole derivatives have been synthesized by treating 1,2,4-triazole-3-thiols with metronidazole tosylate (toluene-4-sulfonic acid 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl ester) in DMF and in the presence of potassium carbonate as a base.
Haythem A. Saadeh, Ibrahim M. Mosleh, Amal G. Al-Bakri, Mohammad S. Mubarak   +3 more
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