Results 31 to 40 of about 14,929 (209)

Physical-chemical properties of 5-(3-fluorophenyl)-4-amino-1,2,4-triazole-3-thiol s-derivatives

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
Introduction. Currently an attempt to combine 1,2,4-triazole heterocycle with various pharmacologically active fragments of other organic molecules is popular among the scientists.
O. A. Bihdan, V. V. Parchenko
doaj   +1 more source

Synthesis of diazole-thiols derivatives from l-cysteine: Characterization, complex formation with Ni(II), Cu(II) and evaluation of their antibacterial activity

Journal of Saudi Chemical Society, 2021
Four novel diazole-thiol derivatives namely: 5-(1-amino-2-sulfanylethyl)-1,3,4-oxadiazole-2(3H)-thione 6, 4-amino-5-(1-amino-2-sulfanylethyl)-4H-1,2,4-triazole-3-thiol 7, 1-amino-3-(1-amino-2-sulfanylethyl)-1H-1,2,4-triazole-5-thiol 8, and 5-(1-amino-2 ...
Mouna Souad Abbassi, Adil Ali Othman, Khaled Briki, Mokhtar Boualem Lahrech   +3 more
doaj   +1 more source

Investigation of the Inhibiting Effect of Some Triazole Derivatives for the Corrosion of Mild Steel in 1 M H2SO4 Solution

International Journal of Electrochemical Science, 2012
The corrosion inhibition of steel in 1.0 M H2SO4 by some triazole derivatives namely, 4-amino-1,2,4-triazole-3-thiol (ATT), 4-amino-5-methyl-1,2,4-triazole-3-thiol (AMTT) and 4-amino-5-ethyl-1,2,4-triazole-3-thiol (AETT) has been studied using ...
Y.H. Ahmad, A.S. Mogoda, A.G. Gadallh
doaj   +1 more source

Synthesis of a Novel 2-((4,5-Diphenyl-4H-1,2,4-triazol-3-yl)thio)acetaldehyde as a Bisulfite Adduct

Molbank, 2023
The scope of the current work was to synthesize an S-alkylated 1,2,4-triazole-3-thiol derivative. Synthesis was carried out in two steps: in the first step, 4,5-diphenyl-4H-1,2,4-triazole-3-thiol was S-alkylated using a halogenated acetal and cesium ...
Beniamin-Nicolae Pintea, Ion Burcă, Valentin Badea, Francisc Peter   +3 more
doaj   +1 more source

Synthesis of 2-(3-chloro-4-nitro-1-benzothien-2-yl)-1,3,4-oxadiazole-1,3,4-thiadiazole and 5-(3-chloro-4-nitro-1-benzothien-2-yl)-4H-1,2,4-triazole-3-thiol [PDF]

مجلة التربية والعلم, 2010
In this paper the synthesis of some substituted 1,3,4-oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole is reported. 3-chloro-4-nitro-2-chloro carbonyl benzo [b] thiophene(1) was synthesized from 2-nitrocinnamic acid by its reaction with thionyl chloride ...
Khalid M. Daoud, Amal N. Ali, Amina A. Ahmed   +2 more
doaj   +1 more source

Antimicrobial activity of new 5-(furan-2-yl)-4-amino-1,2,4-triazole-3-thiol derivatives

Zaporožskij Medicinskij Žurnal, 2017
The aim of this research was to investigate the antimicrobial activity of some new 5-(furan-2-yl)-4-amino-1,2,4-triazole-3-thiol substituents and in some cases to trace the relationship between activity of compounds and their structure.
D. M. Danilchenko, V. V. Parchenko
doaj   +1 more source

Synthesis of some 4-arylidenamino-4H-1,2,4-triazole-3-thiols and their antituberculosis activity

Journal of Enzyme Inhibition and Medicinal Chemistry, 2007
The increasing clinical importance of drug-resistant mycobacterial pathogens has lent additional urgency to microbiological research and new antimycobacterial compound development. For this purpose, new triazoles were synthesized and evaluated for antituberculosis activity.
Özdemir, Ahmet, Turan, Gülhan, Kaplancıklı, Zafer Asım, Chevallet, Pierre   +3 more
openaire   +2 more sources

ADME, Synthesis and Antimycobacterial Activity of 1,2,4-Triazol-3-thiol Linked Phenylacetamide Derivatives

Current Indian Science, 2023
Background:: Tuberculosis (TB) is caused by Mycobacterium tuberculosis and is one of the most contagious and fatal human pathogens which necessitates the development of modified existing drugs or derivatives with action against novel targets. Aims and Objectives:: In the present work, we have explored a few, 2-(5-(substituted)-4H-1,2,4-triazole-2 ...
Trupti Chitre, Shivani Jadhav, Kalyani Asgaonkar, Kunal Pradhan, Kalash Shelke, Shubhangi Thorat, Aniket Bhatambrekar   +6 more
openaire   +1 more source

Synthesis, structure and properties of some 5-R-4-phenyl-1,2,4-triazole-3-thiol derivatives

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
Pyrrole, 1,2,4-triazole and indole derivatives belong to the group of aza-heterocyclic compounds, which have been associated with significant advances in the development of new drugs.
A. S. Hotsulia
doaj   +1 more source

Antibacterial and antifungal activity of derivatives 3-(alkylthio)-4-R-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
The amount of antibiotics has increased over the past decade. This also resulted in increase of microorganisms’ resistance to this class of drugs. Therefore, the synthesis of new compounds that have exhibited antimicrobial and antifungal activity and low
O. A. Suhak, O. І. Panasenko, Ye. G. Knysh, O. M. Kamyshny   +3 more
doaj   +1 more source