Results 61 to 70 of about 84,221 (197)

Arabidopsis TRB Proteins Form Two Closely Related Complexes to Mediate H3K4me3 Demethylation and Transcriptional Repression

Advanced Science, EarlyView.
This study reveals that Arabidopsis telomere repeat binding proteins (TRBs) form two closely related complexes. These complexes mediate H3K4me3 demethylation and transcriptional repression through a positive feedback loop and cooperate with PEAT and PRC2 complexes to regulate multiple histone modifications and gene expression across the genome ...
Qi Wang, Dan‐Yang Yuan, Yu‐Jia Lu, Xin Wang, Hao Zheng, Lin Li, She Chen, Xin‐Jian He   +7 more
wiley   +1 more source

A Review On 1,2,4-Triazoles

, 2012
ABSTRACT Triazole is a five membered heterocyclic system consisting of two carbon atoms and three nitrogen atoms shows wide range of biological activities. Triazoles can be synthesized using Einhorn-Brunner reaction or the Pellizzari reaction from acyl hydrazides and various different method.
openaire   +1 more source

Vacuum Thermal Evaporation for OLEDs: Fundamentals, Optimization, and Implications for Perovskite LEDs

Advanced Electronic Materials, EarlyView.
Vacuum thermal evaporation (VTE) is the dominant method for manufacturing high‐performance small‐molecule organic light‐emitting diodes (OLEDs). Its mature application in OLEDs offers valuable guidance for emerging perovskite light‐emitting diodes (PeLEDs).
Chenxi Shen, Ying Hu, Siqian Zhou, Ziquan He, Junchao Han, Daquan Zhang, Lei Lu, Xiaoliang Mo, Qianpeng Zhang   +8 more
wiley   +1 more source

Antioxidant agents in wartime: prospects for the development of new biologically active compounds based on 1,2,4-triazole derivatives

Український журнал військової медицини
Introduction. This article presents an analysis of the antioxidant activity of 4-amino-5-(2-, 3-, 4-nitrophenyl)-1H-1,2,4-triazole-3-thiones and their synthetic analogues, 5-(4-methoxyphenyl, 3,4,5-trimethoxyphenyl)-1,2,4-triazole-3-thiones and their ...
K. K. Isaycheva, A. G. Kaplaushenko, Yu. G. Sameliuk, O. P. Shmatenko, A. M. Solomennyi   +4 more
doaj   +1 more source

Endogenously Triggered DNAzyme‐Based Nanostructures for Gene‐Combined Therapy

Advanced NanoBiomed Research, EarlyView.
DNAzymes show great promise for gene regulation and therapeutic use via controlled release triggered by endogenous factors. This review summarizes recent advances in designing and constructing nanoscale platforms enabling endogenously triggered release of DNAzyme.
Theoneste Muyizere, Julien Milon Essola, Eric Nyirimigabo, Janvier Mukiza, Jean Felix Mukerabigwi   +4 more
wiley   +1 more source

Synthesis, structure and properties of N-R-amides and hydrazides of 2-[4-R-5-(theophylline-7ʹ-yl)-1,2,4-triazole-3-ylthio]acetic acid

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
One of the most important tasks of modern pharmaceutical science is the search for new biologically active substances, which have high efficacy and low toxicity.
A. S. Gotsulya
doaj   +1 more source

On the Formation of 1,2,4-Triazole-5-Thiol

, 1968
Depending on the nature of acyl group the interaction of an acylhydrazine with thiourea at 125-130° leads to the formation of either 1, 2, 4-triazole-5-thiol or l-acyl thiosemicarbazide. The latter can be converted to triazole-5-thiol by subsequent reaction with sodium ethoxide.
Saktipada Dutta, Auditi Kumar Acharyya, U. P. Basu   +2 more
openaire   +1 more source

3-Phenyl-1H-1,2,4-triazol-5-amine–5-phenyl-1H-1,2,4-triazol-3-amine (1/1)

Acta Crystallographica Section E, 2009
In the title compound, C8H8N4·C8H8N4, two tautomers, viz. 3-phenyl-1,2,4-triazol-5-amine and 5-phenyl-1,2,4-triazol-3-amine, are crystallized together in equal amounts.
Anton V. Dolzhenko, Geok Kheng Tan, Lip Lin Koh, Anna V. Dolzhenko, Wai Keung Chui   +4 more
doaj   +1 more source

Synthesis, antimicrobial and antifungal activity of 3-(2-bromophenyl)-5-(alkylthio)-4-phenyl-4H-1,2,4-triazoles

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2022
To select a molecule that could become a promising pharmacological agent, chemists use already-known heterocyclic bases by adding pharmacologically active groups. One such heterocyclic system is 1,2,4-triazole base, on the basis of which a huge number of
A. A. Safonov, O. I. Panasenko
doaj   +1 more source

Synthesis of Some 1,4-Bis (Substituted 1,3,4-Oxadiazoles and 1,2,4-Triazoles) Benzene From Terephthalic Acid [PDF]

مجلة التربية والعلم, 1999
In this paper the synthesis of some 1,4-bis-(substituted1,3,4-oxadiazoles and 1,2,4-trizoles) benzene from terephthalic acid is reported. Terephthalic acid was esterified with absolute ethanol in presence of concentrated sulfuric acid to give ethyl ...
K. Daoud, E. Mahmood, M. Salih
doaj   +1 more source