Results 11 to 20 of about 185 (123)

NorA Efflux Pump Inhibitors: Expanding SAR Knowledge of Pyrazolo[4,3-c][1,2]benzothiazine 5,5-Dioxide Derivatives [PDF]

Archiv der Pharmazie, Volume 358, Issue 5, May 2025.
Antimicrobial resistance (AMR) represents a significant global concern, driven by the overuse of antibiotics. One of the principal mechanisms contributing to AMR is the activity of microbial efflux pumps (EPs), which expel diverse antibiotics out of ...
Armeni, Tatiana, Barreca, Maria Letizia, Casari, Giulia, Cernicchi, Giada, Di Gregorio, Alessandra, Felicetti, Tommaso, Manfroni, Giuseppe, Massari, Serena, Passamonti, Fabrizio, Rampacci, Elisa, Romaldi, Brenda, Sabatini, Stefano, Tabarrini, Oriana, Vignaroli, Carla, Zefaj, Ermelinda   +14 more
core   +2 more sources

Synthesis of 3-Aminohydantoiny;-1,2-benzothiazine Derivatives [PDF]

Bulletin of the Korean Chemical Society, 2002
By the application of these methods, 1,2-benzothi-azine derivatives with 3-aminohydantoin moiety were pre-pared. Here, we report the synthesis of several new 3-aminohydantoinyl-1,2-benzothiazine derivatives and pro-pose an another mechanism of the cyclization to thehydantoins.3-Aminohydantoins 3a-d were prepared through cycli-zation of the condensation
Myung‐Sook Park, Eun‐Sung Chang, Myung‐Sook Lee, Soon‐Kyoung Kwon   +3 more
openaire   +1 more source

Organic Synthesis via Transition Metal-Catalysis [PDF]

, 2022
This book collects articles published in a Special Issue of Molecules entitled "Organic Synthesis via Transition Metal-Catalysis". Transition metal catalysis is a powerful methodology for the direct synthesis of functionalized, high value-added molecules

core   +1 more source

Synthesis and α-Glucosidase Inhibition Activity of 2-[3-(Benzoyl/4-bromobenzoyl)-4-hydroxy-1,1-dioxido-2H-benzo[e][1,2]thiazin-2-yl]-N-arylacetamides: An In Silico and Biochemical Approach

Molecules, 2021
Diabetes mellitus (DM) is a chronic disorder and has affected a large number of people worldwide. Insufficient insulin production causes an increase in blood glucose level that results in DM.
Furqan Ahmad Saddique, Sana Aslam, Matloob Ahmad, Usman Ali Ashfaq, Muhammad Muddassar, Sadia Sultan, Saman Taj, Muzammil Hussain, Dae Sung Lee, Magdi E. A. Zaki   +9 more
doaj   +1 more source

Synthesis of Bioactive Hydroxytyrosol Esters via Multienzyme Cascade on Electroactive Melanin Lignin Nanoparticles: A One‐Pot Approach without Extra Reducing Agents

ChemCatChem, Volume 15, Issue 14, July 21, 2023., 2023
Bioactive hydroxytyrosol esters from tyrosol and lipophilic carboxylic acids are synthesized by multienzyme cascade immobilized on electroactive melanin lignin nanoparticles. Abstract A one‐pot strategy for the synthesis of bioactive hydroxytyrosol esters from tyrosol and lipophilic carboxylic acids has been developed via multienzyme cascade ...
Davide Piccinino, Valentina Ubertini, Eliana Capecchi, Elisabetta Tomaino, Valeria Gigli, Raffaele Saladino   +5 more
wiley   +1 more source

1,2-Benzothiazines. IV. 1

Journal of Medicinal Chemistry, 1967
Harold. Zinnes, John. Shavel, Roger A. Comes   +2 more
core   +2 more sources

Rhodium(III)-Catalyzed Synthesis of 1,2-Benzothiazines

Synfacts, 2015

core   +2 more sources

Phenolic Polymers as Model Melanins

Macromolecular Chemistry and Physics, Volume 224, Issue 14, July 2023., 2023
Polymerization of a variety of phenolic monomers (CAT, DOPA, or HGA) yields conjugated polymers (polyCATs, polyDOPAs, or polyHGA‐HS, respectively) which are simplified versions of biologically generated melanins. Their chemical, paramagnetic, and electrical properties are analyzed to assess if there may be a correlation between the functional groups ...
Hanaa A. Galeb, Jonas Eichhorn, Sam Harley, Alexander J. Robson, Laurine Martocq, Steven J. Nicholson, Mark D. Ashton, Hend A. M. Abdelmohsen, Emel Pelit, Sara J. Baldock, Nathan R. Halcovitch, Benjamin J. Robinson, Felix H. Schacher, Victor Chechik, Koen Vercruysse, Adam M. Taylor, John G. Hardy   +16 more
wiley   +1 more source

Neuromelanins in brain aging and Parkinson's disease: synthesis, structure, neuroinflammatory, and neurodegenerative role

IUBMB Life, Volume 75, Issue 1, Page 55-65, January 2023., 2023
Abstract Neuromelanins are compounds accumulating in neurons of human and animal brain during aging, with neurons of substantia nigra and locus coeruleus having the highest levels of neuromelanins. These compounds have melanic, lipid, peptide, and inorganic components and are contained inside special autolysosomes.
Fabio A. Zucca, Andrea Capucciati, Chiara Bellei, Michał Sarna, Tadeusz Sarna, Enrico Monzani, Luigi Casella, Luigi Zecca   +7 more
wiley   +1 more source

Benzo[c][1,2]thiazine‐Based Analogs in the Inverse Electron Demand [4+2] Hetero Diels‐Alder Reaction with Glycals: Access to Tetracyclic Fused Galactose and Fucose Derivatives

European Journal of Organic Chemistry, Volume 2022, Issue 43, November 18, 2022., 2022
The N‐substituted‐3‐thioxo‐benzo[c][1,2]thiazin‐4‐one‐2,2‐dioxides are an original class of highly reactive electron‐poor heterodienes that allow easy access to unprecedented benzo‐thiazine bearing galactose and fucose derivatives in a remarkably selective way. Abstract The synthesis and reactivity in an [4+2] inverse electron demand hetero Diels‐Alder
Giacomo Biagiotti, Laura Legnani, Giusi Aresta, Maria A. Chiacchio, Barbara Richichi   +4 more
wiley   +1 more source