Results 11 to 20 of about 202 (136)

Synthesis and Transformations of NH-Sulfoximines. [PDF]

open access: yesChemistry, 2021
This review considered recent progress and achievements in the synthesis and transformation of NH‐sulfoximines. The development of strategies for direct and selective preparation of NH‐sulfoximines, even in enantioenriched form or by using sustainable approaches and continuous flow synthesis, are reported. Transformations of sulfoximines by N−S, N−P, N−
Andresini M   +4 more
europepmc   +2 more sources

Anti-Inflammatory Activity of 1,2-Benzothiazine 1,1-Dioxide Derivatives. [PDF]

open access: yesPharmaceuticals (Basel)
There is an urgent need to develop new anti-inflammatory compounds due to the versatility of their applications and the side effects associated with currently used nonsteroidal anti-inflammatory drugs (NSAIDs). Compounds containing the 1,2-benzothiazine 1,1-dioxide moiety in their structure have demonstrated a broad range of pharmacological activities,
Szczęśniak-Sięga BM, Topolska I.
europepmc   +3 more sources

Synthesis of 3‐Aminohydantoinyl‐1,2‐benzothiazine Derivatives. [PDF]

open access: yesChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Myung‐Sook Park   +3 more
openaire   +2 more sources

Chiral Phosphoric Acids as Versatile Tools for Organocatalytic Asymmetric Transfer Hydrogenations. [PDF]

open access: yesEuropean J Org Chem, 2021
Organocatalytic asymmetric transfer hydrogenation provides a metal‐free and ambient alternative to classical reductions. Chiral phosphoric acid‐catalysis represents a powerful strategy in this field, with a range of novel and selective methods for various double bond reductions.
Pálvölgyi ÁM   +3 more
europepmc   +2 more sources

Synthesis of Bioactive Hydroxytyrosol Esters via Multienzyme Cascade on Electroactive Melanin Lignin Nanoparticles: A One‐Pot Approach without Extra Reducing Agents

open access: yesChemCatChem, Volume 15, Issue 14, July 21, 2023., 2023
Bioactive hydroxytyrosol esters from tyrosol and lipophilic carboxylic acids are synthesized by multienzyme cascade immobilized on electroactive melanin lignin nanoparticles. Abstract A one‐pot strategy for the synthesis of bioactive hydroxytyrosol esters from tyrosol and lipophilic carboxylic acids has been developed via multienzyme cascade ...
Davide Piccinino   +5 more
wiley   +1 more source

Phenolic Polymers as Model Melanins

open access: yesMacromolecular Chemistry and Physics, Volume 224, Issue 14, July 2023., 2023
Polymerization of a variety of phenolic monomers (CAT, DOPA, or HGA) yields conjugated polymers (polyCATs, polyDOPAs, or polyHGA‐HS, respectively) which are simplified versions of biologically generated melanins. Their chemical, paramagnetic, and electrical properties are analyzed to assess if there may be a correlation between the functional groups ...
Hanaa A. Galeb   +16 more
wiley   +1 more source

Neuromelanins in brain aging and Parkinson's disease: synthesis, structure, neuroinflammatory, and neurodegenerative role

open access: yesIUBMB Life, Volume 75, Issue 1, Page 55-65, January 2023., 2023
Abstract Neuromelanins are compounds accumulating in neurons of human and animal brain during aging, with neurons of substantia nigra and locus coeruleus having the highest levels of neuromelanins. These compounds have melanic, lipid, peptide, and inorganic components and are contained inside special autolysosomes.
Fabio A. Zucca   +7 more
wiley   +1 more source

Benzo[c][1,2]thiazine‐Based Analogs in the Inverse Electron Demand [4+2] Hetero Diels‐Alder Reaction with Glycals: Access to Tetracyclic Fused Galactose and Fucose Derivatives

open access: yesEuropean Journal of Organic Chemistry, Volume 2022, Issue 43, November 18, 2022., 2022
The N‐substituted‐3‐thioxo‐benzo[c][1,2]thiazin‐4‐one‐2,2‐dioxides are an original class of highly reactive electron‐poor heterodienes that allow easy access to unprecedented benzo‐thiazine bearing galactose and fucose derivatives in a remarkably selective way. Abstract The synthesis and reactivity in an [4+2] inverse electron demand hetero Diels‐Alder
Giacomo Biagiotti   +4 more
wiley   +1 more source

Sulfoximine‐Directed Arene ortho‐Lithiation

open access: yesEuropean Journal of Organic Chemistry, Volume 2021, Issue 46, Page 6229-6246, December 14, 2021., 2021
The growing importance of sulfoximines in medicinal chemistry has led to a renewed interest in their synthesis and functionalization. This review describes the directed ortho‐lithiation of S‐aryl sulfoximines. Discussed are the synthesis and reactivity of five different types of o‐lithiosulfoximines, including o‐lithiosulfoximines with and without α ...
Hans‐Joachim Gais
wiley   +1 more source

Nature‐Inspired Functional Chromophores from Biomimetic o‐Quinone Chemistry

open access: yesEuropean Journal of Organic Chemistry, Volume 2021, Issue 21, Page 2982-2989, June 7, 2021., 2021
Bioinspired manipulation of o‐quinones generated from natural catechols represents a straightforward strategy to access the diverse molecular scaffolds endowed with peculiar functional chromophores, which offers a finely tunable palette of colors, emissions and input/output opportunities in response to pH, light, oxidant species and other external ...
Maria Laura Alfieri   +4 more
wiley   +1 more source

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