Results 1 to 10 of about 166 (105)

Synthesis and Antimicrobial Activity of 1,2-Benzothiazine Derivatives [PDF]

Molecules, 2016
A number of 1,2-benzothiazines have been synthesized in a three-step process. Nine chalcones 1–9 bearing methyl, fluoro, chloro and bromo substituents were chlorosulfonated with chlorosulfonic acid to generate the chalcone sulfonyl chlorides 10–18. These
Chandani Patel, Jatinder P. Bassin, Mark Scott, Jenna Flye, Ann P. Hunter, Lee Martin, Madhu Goyal   +6 more
doaj   +12 more sources

Methyl 4-ethoxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide [PDF]

Acta Crystallographica Section E, 2008
In the crystal structure of the title compound, C13H15NO5S, the molecules exhibit weak S=O...H—C and C=O...H—C intermolecular interactions and arrange themselves into centrosymmetric dimers by means of π–π interactions (ring ...
Muhammad Zia-ur-Rehman, Jamil Anwar Choudary, Mark R. J. Elsegood, Noshin Akbar, Hamid Latif Siddiqui   +4 more
doaj   +3 more sources

N-(3,4-Dimethylphenyl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide [PDF]

Acta Crystallographica Section E, 2009
1,2-Benzothiazines similar to the title compound, C18H18N2O4S, are well known in the literature for their biological activities and are used as medicines in the treatment of inflammation and rheumatoid arthritis. The thiazine ring adopts a distorted half-
Waseeq Ahmad Siddiqui, Muhammad Ali, Muhammad Zia-ur-Rehman, Saima Sharif, Graham John Tizzard   +4 more
doaj   +2 more sources

Sulfoximines-Assisted Rh(III)-Catalyzed C–H Activation and Intramolecular Annulation for the Synthesis of Fused Isochromeno-1,2-Benzothiazines Scaffolds under Room Temperature [PDF]

Molecules, 2020
A mild and facile Cp*Rh(III)-catalyzed C–H activation and intramolecular cascade annulation protocol has been proposed for the furnishing of highly fused isochromeno-1,2-benzothiazines scaffolds using S-phenylsulfoximides and 4-diazoisochroman-3-imine as
Bao Wang, Xu Han, Jian Li, Chunpu Li, Hong Liu   +4 more
doaj   +3 more sources

Sulfoximine Assisted C–H Activation and Annulation via Vinylene Transfer: Access to Unsubstituted Benzothiazines

Molecules, 2023
In this study, we report the synthesis of unsubstituted 1,2-benzothiazines through a redox-neutral Rh(III)-catalyzed C–H activation and [4+2]-annulation of S–aryl sulfoximines with vinylene carbonate.
Koneti Kondalarao, Somratan Sau, Akhila K. Sahoo   +2 more
doaj   +2 more sources

Evaluation of 1,2-Benzothiazine 1,1-Dioxide Derivatives In Vitro Activity towards Clinical-Relevant Microorganisms and Fibroblasts

Molecules, 2020
The global concern related with growing number of bacterial pathogens, resistant to numerous antibiotics, prone scientific environment to search for new antimicrobials.
Ruth K. Dudek-Wicher, Berenika M. Szczęśniak-Sięga, Rafał J. Wiglusz, Jan Janczak, Marzenna Bartoszewicz, Adam F. Junka   +5 more
doaj   +2 more sources

α-Chloroketones enabled Rh(III)-catalyzed enantioselective C–H [4+2] annulation of sulfoximines under mild and redox-neutral conditions

Green Synthesis and Catalysis
Taking advantage of facilely available α-chloroketones as C(sp3)-based electrophilic partners and oxidized alkyne equivalents, we here present a novel CpxRh(III)-catalyzed enantioselective C–H [4 ​+ ​2] annulation of sulfoximines under mild and redox ...
Qingwei Song, Wenhao Wu, Weijie Chen, Hui Gao, Zhi Zhou, Zhongyi Zeng, Wei Yi   +6 more
doaj   +2 more sources

Synthesis of 1,2-Benzothiazines via C–H Activation/Cyclization in a Recyclable, Mild System

ACS Sustainable Chemistry and Engineering, 2019
A mild and recyclable protocol to synthesize 1,2-benzothiazines by Rh­(III)-catalyzed C–H activation/cyclization of NH-sulfoximines in ionic liquids with high yields is described.
Li Hai, Yong Wu
exaly   +2 more sources

Modular Synthesis of 1,2-Benzothiazines and 1,2-Benzothiazine 1‑Imines via Palladium-Catalyzed C–H/C–C Activation Reactions

The Journal of Organic Chemistry
In this study, a modular approach toward cyclic sulfoximines and sulfondiimines via palladium-catalyzed intramolecular C–H/C-C activation reactions was reported.
Fan Teng (1581460), Limin Yu (759361), Lisha Mo (17987540), Minhai Yin (17987543), Yali Wang (332169), Yifan Ren (8460162), Yimiao He (1651798), Zhuang Xiong (335710)   +7 more
core   +3 more sources

THE SYNTHESIS OF SOME NEW 1,2-BENZOTHIAZINES [PDF]

Organic Preparations and Procedures International, 1980
Joseph G. Lombardino
core   +2 more sources