Results 1 to 10 of about 28,125 (246)

Electrocyclic Ring‐Opening of 1,2,4‐Oxadiazole[4,5‐a]piridinium Chloride: a New Route to 1,2,4‐Oxadiazole Dienamino Compounds

ChemistryOpen, 2019
1,2,4‐Oxadiazole[4,5‐a]piridinium chloride adds nucleophiles to undergo electrocyclic ring opening affording 1,2,4‐oxadiazole dienamino derivatives. These pyridinium salts represent a special class of Zincke salts that are prone to rearrange when treated
Dr. Stefano Carella, Dr. Misal Giuseppe Memeo, Prof. Paolo Quadrelli   +2 more
doaj   +1 more source

Engineering Photolabile Cyclopentane‐Fused Coumarins: From One‐Pot Synthesis to Mechanistic Study for Visible Light‐Triggered Photolysis

Chemistry – An Asian Journal, Volume 20, Issue 19, October 3, 2025.
Cyclopentane fusion in coumarin photocages transforms their behavior from rapid SN1‐mediated release (minutes) to a slower elimination pathway (hours), accompanied by dramatic spectral changes upon photolysis, providing complementary tools for controlled‐release applications requiring different payload delivery rates.
Jau‐Tien Lin, Hsuan‐Yu Lin, Tai‐Chung Lo, Chih‐Ling Lin, Yi‐Hsien Li, Wei‐Hao Wu, Ting‐Yi Hsieh, Shun‐Yuan Luo, Chih‐Chien Chu   +8 more
wiley   +1 more source

SuFExable NH-Pyrazoles via 1,3-Dipolar Cycloadditions of Diazo Compounds with Bromoethenylsulfonyl Fluoride. [PDF]

J Org Chem, 2022
Yamanushkin P, Kaya K, Feliciano MAM, Gold B.   +3 more
europepmc   +1 more source

A Fullerene‐Based Selenosugar Ball

European Journal of Organic Chemistry, Volume 28, Issue 36, September 29, 2025.
A fullerene hexakis‐adduct decorated with 12 peripheral seleno‐d‐talitol moieties is synthesized efficiently with a Th‐symmetry from a hexakis‐adduct of [60]fullerene prepared by a cycloaddition reaction and subsequent copper‐catalyzed azide‐alkyne cycloaddition click chemistry.
Reinier Lemos, Yoana Pérez‐Badell, Mauro De Nisco, Giovanna Cimmino, Claudia González, Andrea Carpentieri, Severina Pacifico, Margarita Suárez, Silvana Pedatella   +8 more
wiley   +1 more source

Acceleration of 1,3-Dipolar Cycloadditions by Integration of Strain and Electronic Tuning. [PDF]

J Am Chem Soc, 2021
Dones JM, Abularrage NS, Khanal N, Gold B, Raines RT.   +4 more
europepmc   +1 more source

Synthesis and Evaluation of DNA Cross‐linkers by Click Chemistry‐Mediated Heterodimerization of Nor‐Tomaymycins

Chemistry – A European Journal, Volume 31, Issue 53, September 19, 2025.
Click chemistry promises a simple method to produce pyrrolo[2,1‐c][1,4]benzodiazepine (PBD)‐based DNA binders. DNA binding and covalent crosslinking capabilities have been validated for ‘clicked’ PBD heterodimers using thermal denaturation analysis, mass spectrometry and DNase I footprinting.
Julia Friederich, Katharina Rox, Hazel L. S. Fuchs, Md. Mahbub Hasan, Patrick Raunft, David E. Thurston, Keith R. Fox, Khondaker Miraz Rahman, Mark Brönstrup   +8 more
wiley   +1 more source

Regio- and Diastereoselective 1,3-Dipolar Cycloadditions of 1,2,4-Triazin-1-ium Ylides: a Straightforward Synthetic Route to Polysubstituted Pyrrolo[2,1-f][1,2,4]triazines. [PDF]

ACS Omega, 2022
Galeta J, Šlachtová V, Dračínský M, Vrabel M.   +3 more
europepmc   +1 more source

Mechanistic Study of the Light‐Initiated Generation of Free Diazoalkanes: Towards Photo‐Orthogonal Synthesis

ChemistryEurope, Volume 3, Issue 5, September 18, 2025.
A combined computational and experimental study elucidates the mechanism of the light‐induced formation of free diazoalkanes in detail. Starting from deprotonated tosylhydrazone as the light‐harvesting species, it undergoes bond dissociation from a charge transfer state.
Ferdinand L. Pointner, Jonas Poll, Elina K. Taskinen, Vincent George, Tristan Ruff, Florian Rott, Gabriel Mayer, Niklas Gessner, Roger‐Jan Kutta, Burkhard König, Patrick Nuernberger, Christian Ochsenfeld, Regina de Vivie‐Riedle   +12 more
wiley   +1 more source

Nitropyridines as 2π-Partners in 1,3-Dipolar Cycloadditions with N-Methyl Azomethine Ylide: An Easy Access to Condensed Pyrrolines. [PDF]

Molecules, 2021
Bastrakov MA, Fedorenko AK, Starosotnikov AM, Shakhnes AK.   +3 more
europepmc   +1 more source

The Azidofunctionalization of Alkenes

ChemistryEurope, Volume 3, Issue 5, September 18, 2025.
The azidofunctionalization of alkenes offers a powerful strategy for synthesizing nitrogen‐containing compounds by installing both an azide and a second functional group in one step. This approach, employing photoredox catalysis, transition metals, and radical methods, is efficient, selective, and versatile, with applications in pharmaceuticals and ...
Pierre Palamini, Jerome Waser
wiley   +1 more source