Results 101 to 110 of about 28,125 (246)

Asymmetric Lewis acid-catalyzed 1,3-dipolar cycloadditions [PDF]

, 2017
Highly tuned, one-point binding chiral iron and ruthenium complexes selectively coordinate and activate α,β-unsaturated aldehydes and ketones toward asymmetric catalytic Diels-Alder cycloaddition reactions.
Brinkmann, Yasmin, Bădoiu, Andrei, Kündig, E. Peter, Viton, Florian   +3 more
core  

Inverse electron-demand 1,3-dipolar cycloaddition of nitrile oxide with common nitriles leading to 3-functionalized 1,2,4-oxadiazoles [PDF]

, 2011
A carbamoyl-substituted nitrile oxide was generated upon treatment of easily available 2-methyl-4-nitro-3-isoxazolin-5(2H)-one with THF (not dried); the reaction proceeded efficiently even in the absence of any special reagents and reaction conditions ...
1020, 1021, 1022, 1023, 1024, 1025, 1026, 1027, Ariga, Masahiro, Hirao, Shotaro, Ise, Yumiko, Kobiro, Kazuya, Nishiwaki, Nagatoshi, Okajima, Yoshikazu, Saigo, Kazuhiko, Sawayama, Jun   +15 more
core   +1 more source

Identification of a New Interesting BAG3 Modulator Able to Disrupt Cancer‐Related Pathways

ChemMedChem, EarlyView.
Compound 2, identified through in‐house screening and derived from SP18, exhibits high affinity for BAG3, as demonstrated by Surface Plasmon Resonance and docking studies. It induces a dose‐dependent proapoptotic response in HeLa cells, evidenced by increased Annexin V/PI staining, underscoring the triazole scaffold as a promising platform for BAG3 ...
Dafne Ruggiero, Eleonora Boccia, Emis Ingenito, Vincenzo Vestuto, Gilda D’Urso, Alessandra Capuano, Agostino Casapullo, Stefania Terracciano, Giuseppe Bifulco, Gianluigi Lauro, Ines Bruno   +10 more
wiley   +1 more source

Solvent Effects on the Selectivity of Ambimodal Dipolar/Diels–Alder Cycloadditions: A Study Using Explicit Solvation Models

ChemPhysChem, EarlyView.
Post‐transition state bifurcation in the reaction of 2‐aminoacrolein with 1,3‐butadiene is investigated using explicit solvation (up to 45 water molecules). GFN2‐xTB dynamics reveal strong solvent‐size effects on branching to (4 + 2) and (4 + 3) cycloadducts via an ambimodal transition state.
Hayato Matsubuchi, Daiki Hayashi, Daichi Okamoto, Aoi Noguchi, Shoto Nakagawa, Toshiyuki Takayanagi, Tatsuhiro Murakami   +6 more
wiley   +1 more source

Pyrrolodiazines. 4. Structure and chemistry of 3,4-dihydropyrrolo[1,2-a]pyrazine [PDF]

, 1997
The structure of 3,4-dihydropyrrolo[1,2-a]pyrazine and its N-protonated form is studied by ab initio calculations. Examples of the reactivity of this poorly studied system are presented in which it is shown that the imino moiety does not react with ...
Andrés, José L. de, Castaño González, Obis Dionisio, Castellote Álvaro, María Isabel, García Navío, José Luis, Minguez Ortega, José Miguel, Vaquero López, Juan José, Álvarez-Builla Gómez, Julio   +6 more
core   +3 more sources

Reactions of 1,2,4‐Oxadiazole[4,5‐a]piridinium Salts with Alcohols: the Synthesis of Alkoxybutadienyl 1,2,4‐Oxadiazoles

ChemistryOpen, 2020
1,2,4‐Oxadiazole[4,5‐a]piridinium salts add alcohols and alkoxides to undergo electrocyclic ring opening affording alkoxybutadienyl 1,2,4‐oxadiazole derivatives.
Dr. Mattia Moiola, Dr. Marco Leusciatti, Prof. Dr. Paolo Quadrelli   +2 more
doaj   +1 more source

5-Formyltriazoles as Valuable Starting Materials for Unsymmetrically Substituted Bi-1,2,3-Triazoles

Frontiers in Chemistry, 2020
Herein, we present the first synthetic methodologies toward non-symmetrical 5,5′-C, C-linked bi-1,2,3-triazoles starting from 5-formyl-1,2,3-triazole via two related pathways.
Robby Vroemans, Tomas Horsten, Maarten Van Espen, Wim Dehaen   +3 more
doaj   +1 more source

Electrochemical Dehydration Reaction

ChemSusChem, EarlyView.
Electrochemical dehydration reactions are a fascinating and underexplored field of research in the domain of electrosynthesis. They offer a sustainable alternative to hazardous and harsh dehydration reagents. In this review, the recent progress that has been made in this emerging research topic is surveyed.
Johannes Schneider, Enrico Lunghi, Siegfried R. Waldvogel   +2 more
wiley   +1 more source

Binap-silver-catalyzed enantioselective multicomponent 1,3-dipolar cycloaddition of azomethines ylides derived from ethyl glyoxylate [PDF]

, 2015
The enantioselective binap–silver catalyzed multicomponent 1,3-dipolar cycloaddition using ethyl glyoxylate, phenylalanine ethyl ester, and maleimides is described. The employment of basic silver carbonate allows the reaction to take place in the absence
Mancebo Aracil, Juan, Nájera, Carmen, Sansano, Jose M.   +2 more
core   +2 more sources

The Fragmentation of 2,3-Dihydroisothiazol-3-one 1,1-Dioxide Derivatives: A Novel Cheletropic Process

CHIMIA, 1992
Adducts obtained by 1,3-dipolar cycloadditions to 2,3-dihydroisothiazol-3-one 1,1-dioxides are inclined to undergo a cheletropic process, by which the newly formed heterocyclic part undergoes aromatization, while SO2 is extruded and an ...
Kaspar F. Burri
doaj   +2 more sources