Dynamic Catalytic Highly Enantioselective 1,3-Dipolar Cycloadditions. [PDF]
Angew Chem Int Ed Engl, 2021 AbstractIn dynamic covalent chemistry, reactions follow a thermodynamically controlled pathway through equilibria. Reversible covalent‐bond formation and breaking in a dynamic process enables the interconversion of products formed under kinetic control to thermodynamically more stable isomers.
Yildirim O +5 more
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Green Protocols in Heterocycle Syntheses via 1,3-Dipolar Cycloadditions [PDF]
Frontiers in Chemistry, 2019 The aim of this review is to provide an overview of green protocols for the organic synthesis of heterocycles via 1,3-dipolar cycloaddition. Particular attention has been devoted to the use of green solvents; reactions performed in ionic liquids ...
Katia Martina +4 more
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Mechanistic DFT Study of 1,3-Dipolar Cycloadditions of Azides with Guanidine [PDF]
Molecules, 2023 Density functional calculations SMD(chloroform)//B3LYP/6-311+G(2d,p) were employed in the computational study of 1,3-dipolar cycloadditions of azides with guanidine.
Ivana Antol +2 more
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ChemInform Abstract: 1,3‐Dipolar Cycloadditions of Azomethine Imines [PDF]
ChemInform, 2015 AbstractReview: [162 refs.
Nájera, Carmen +2 more
core +9 more sources
Activation of Dinitrogen as A Dipolarophile in 1,3-Dipolar Cycloadditions: A Theoretical Study Using Nitrile Imines as “Octet” 1,3-Dipoles [PDF]
Scientific Reports, 2017 Theoretical calculations at the G4MP2 level of theory demonstrate that it is possible to activate dinitrogen to make it react in dipolar cycloadditions using neutral beryllium derivatives and other neutral metallic compounds.
M. Merced Montero-Campillo +2 more
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Understanding the 1,3-Dipolar Cycloadditions of Allenes. [PDF]
Chemistry, 2020 AbstractWe have quantum chemically studied the reactivity, site‐, and regioselectivity of the 1,3‐dipolar cycloaddition between methyl azide and various allenes, including the archetypal allene propadiene, heteroallenes, and cyclic allenes, by using density functional theory (DFT).
Yu S +4 more
europepmc +7 more sources
An Overlooked Pathway in 1,3-Dipolar Cycloadditions of Diazoalkanes with Enamines. [PDF]
Angew Chem Int Ed Engl, 2022 AbstractMethyl diazoacetate reacts with 1‐(N‐pyrrolidino)cycloalkenes to give products of 1,3‐dipolar cycloadditions and azo couplings. The kinetics and mechanisms of these reactions were investigated by NMR spectroscopy and DFT calculations. Orthogonal π‐systems in the 1,3‐dipoles of the propargyl‐allenyl type allow for two separate reaction pathways ...
Li L +5 more
europepmc +5 more sources
1,3-Dipolar cycloadditions of acridine with nitrile oxides [PDF]
ARKIVOC, 2002 Siteand regio-isomeric mono-cycloadducts 9 are formed in the reactions of mesito1b and dichloromesitonitrile oxide 1c with acridine 6 in a 1:2 ratio, while the reaction of 1b and 6 in a 10:1 ratio afforded, besides the mono-cycloadduct 9b and traces of the corresponding oxime 10b, the bis-cycloadduct 12 with the opposite regiochemistry to that of the ...
Antonino Corsaro +5 more
doaj +9 more sources
Decarboxylative 1,3-dipolar cycloadditions of l-proline. [PDF]
RSC Advl-Proline is widely used in 1,3-dipolar cycloaddition reactions. Azomethine ylide derived from decarboxylative condensation of l-proline and 1,2-dicarbonyl compounds can directly react with various dipolarophiles through 1,3-dipolar cycloaddition.
Doraghi F +6 more
europepmc +3 more sources
Decarboxylation-Driven Double Annulations: Innovative Multi-Component Reaction Pathways [PDF]
MoleculesA concerted five-component reaction strategy has been developed, featuring double [3+2] cycloadditions utilizing aspartic acid. This approach provides valuable insights into mechanistic pathways, allowing for the distinction between concerted and ...
Desheng Zhan +4 more
doaj +2 more sources