Decarboxylative 1,3-dipolar cycloadditions of l-proline. [PDF]
RSC Advl-Proline is widely used in 1,3-dipolar cycloaddition reactions. Azomethine ylide derived from decarboxylative condensation of l-proline and 1,2-dicarbonyl compounds can directly react with various dipolarophiles through 1,3-dipolar cycloaddition.
Doraghi F +6 more
europepmc +3 more sources
Triazol-substituted titanocenes by strain-driven 1,3-dipolar cycloadditions [PDF]
Beilstein Journal of Organic Chemistry, 2014 An operationally simple, convenient, and mild strategy for the synthesis of triazole-substituted titanocenes via strain-driven 1,3-dipolar cycloadditions between azide-functionalized titanocenes and cyclooctyne has been developed.
Andreas Gansäuer +5 more
doaj +2 more sources
Intermolecular 1,3-dipolar cycloadditions of azomethine imines [PDF]
ARKIVOC, 2006 Dipolar cycloadditions of azomethine imines, formed in situ from aldehydes and N1-alkyl-N2-acylhydrazines, with electron-deficient dipolarophiles produce pyrazolidines: mono-substituted dipolarophiles afford principally 4-substituted pyrazolidines.
Raymond C. F. Jones +2 more
doaj +4 more sources
1,3-Dipolar cycloadditions of azomethine imines [PDF]
ChemInform, 2015 Azomethine imines are considered 1,3-dipoles of the aza-allyl type which are transient intermediates and should be generated in situ but can also be stable and isolable compounds.
Nájera, Carmen +2 more
core +8 more sources
Sydnone-Based Approach to Heterohelicenes through 1,3-Dipolar-Cycloadditions. [PDF]
J Am Chem Soc, 2019 The first approach to pyrazole-containing helicenes via sydnone-aryne [3 + 2]-cycloaddition is described. An unprecedented regioselectivity in the cycloaddition step toward the more sterically constrained product was observed in the presence of extended aromatic scaffolds. DFT calculations enabled understanding the origin of this unexpected selectivity.
Yen-Pon E +10 more
europepmc +12 more sources
Synthesis of 2-substituted 9-oxa-guanines {5-aminooxazolo[5,4-d]pyrimidin-7(6H)-ones} and 9-oxa-2-thio-xanthines {5-mercaptooxazolo[5,4-d]pyrimidin-7(6H)-ones} [PDF]
Beilstein Journal of Organic Chemistry, 2008 Oxazolo[5,4-d]pyrimidines can be considered as 9-oxa-purine analogs of naturally occurring nucleic acid bases. Interest in this ring system has increased due to recent reports of biologically active derivatives.
Subrata Mandal +4 more
doaj +4 more sources
Multicomponent syntheses of pyrazoles via (3 + 2)-cyclocondensation and (3 + 2)-cycloaddition key steps [PDF]
Beilstein Journal of Organic ChemistryPyrazoles are rarely found in nature but are traditionally used in the agrochemical and pharmaceutical industries, while other areas of use are also actively developing. However, they have also found numerous other applications.
Ignaz Betcke +3 more
doaj +2 more sources
Quantitative Dynamics of the N2O + C2H2 → Oxadiazole Reaction: A Model for 1,3-Dipolar Cycloadditions [PDF]
ACS Omega, 2020 Yang Liu, Jun Li
doaj +2 more sources
[3+2] Cycloaddition of alkyl aldehydes and alkynes enabled by photoinduced hydrogen atom transfer
Nature Communications, 2022 In contrast to the prevalence of 1,3-dipolar cycloadditions, radical [3+2] annulations of alkynes are underexplored. Here, the authors describe [3+2] cycloadditions of various internal alkynes with readily accessible aliphatic aldehydes via photoinduced ...
Siya Le +6 more
doaj +1 more source
Deterministic Covalent Organic Functionalization of Monolayer Graphene with 1,3-Dipolar Cycloaddition Via High Resolution Surface Engineering [PDF]
J. Mater. Chem. C 11 (2023) 2630 - 2639, 2022 Spatially-resolved organic functionalization of monolayer graphene is successfully achieved by combining low-energy electron beam irradiation with 1,3-dipolar cycloaddition of azomethine ylide. Indeed, the modification of the graphene honeycomb lattice obtained via electron beam irradiation yields to a local increase of the graphene chemical reactivity.
arxiv +1 more source