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Solid state photochemistry of 1,4-dihydropyridines

Bioorganic and Medicinal Chemistry Letters, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Hamid Reza Memarian, Arsalan Mirjafari
exaly   +3 more sources

Coumarin 1,4-Dihydropyridine Derivatives

Bioorganic & Medicinal Chemistry, 1998
A series of 1,4-dihydropyridines bearing a coumarin moiety in 4-position was synthesized. The compounds were evaluated for inotropic, chronotropic and calcium antagonist activities. The replacement of the o-nitrophenyl moiety of nifedipine with a coumarin or phenylcoumarin system is accompanied by a decrease of the activity on myocardial and vascular ...
Valenti P.   +4 more
openaire   +2 more sources

Iodocyclization of 1,4-dihydropyridines

Tetrahedron Letters, 1998
Abstract Iodine (or related species) addition to 1,4-dihydropyridines, with properly attached substituents at the nitrogen atom, leads to the corresponding 3-iodotetrahydropyridinium ions, which undergo an internal nucleophilic attack to furnish regio- and stereoselectively iodobi(poly)lteterocyclic ring systems in good yields.
Rodolfo Lavilla   +3 more
openaire   +1 more source

The oxidation of 1,4-dihydropyridines

Chemistry of Heterocyclic Compounds, 1970
The olefinic bond of methenylbisindan-1,3-dione, 2-benzylideneindan-1, 3-dione, and its derivatives is easily reduced by many 1, 4-dihydropyridines. Under the conditions described, other functional groups are untouched. These Β-dicarbonyl compounds are utilized to compare the effects of substituents in 1,4-dihydropyridines on their reactivity in the ...
G. Ya. Dubur, Ya. R. Uldrikis
openaire   +1 more source

The photochemistry of 3,5-disubstituted 1,4-dihydropyridines

Tetrahedron, 1970
Abstract On irradiation, 1,4-dihydropyridines have been shown to undergo three types of reaction: disproportionation, isomerization and dimerization. The presence of 2,6-substituents inhibits these reactions except in the case of 3a which undergoes disproportionation.
U, Eisner   +3 more
openaire   +2 more sources

1,4-Dihydropyridine activators in the tiamdipine series

European Journal of Pharmacology, 1990
The pharmacologic and radioligand binding properties of 5-nitro analogs of the 1,4-dihydropyridine Ca2+ channel antagonist, tiamdipine (2-(2-aminoethylthio)methyl-3-carbomethoxy-5-carbomethoxy-6-m ethyl-4-(3-nitrophenyl)-1,4-dihydropyridine) and its N-formyl derivative have been measured in rat tail artery, guinea pig ileum and rat heart.
GALLETTI, FERRUCCIO   +2 more
openaire   +3 more sources

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