Results 51 to 60 of about 47,076 (120)

Scientific and technical assistance to the evaluation of the safety of calcidiol monohydrate as a novel food

EFSA Journal, Volume 22, Issue 1, January 2024.
Abstract EFSA was asked by the European Commission to provide scientific assistance with respect to the EFSA adopted scientific opinion on ‘Safety of calcidiol monohydrate produced by chemical synthesis as a novel food pursuant to Regulation (EU) 2015/2283’, including its bioavailability as a metabolite of vitamin D3 when added for nutritional purposes
European Food Safety Authority (EFSA), Dominique Turck, Harry J. McArdle, Androniki Naska, Monika Neuhäuser‐Berthold, Giovanni Passeri, Ionut Craciun, Ruth Roldán‐Torres, Silvia Valtueña Martínez   +8 more
wiley   +1 more source

The role of the coactivators PGC-1α and PGC-1β in retina and skeletal muscle [PDF]

, 2011
Peroxisome proliferator-activated receptor γ coactivator- 1 (PGC-1) designates a family of coactivators consisting of PGC-1α, PGC-1β and PRC. By associating with transcription factors like nuclear receptors, they induce transcription of target genes that
Egger, A, Egger, Anna Franziska
core   +1 more source

Loss of Renal Tubular PGC-1α Exacerbates Diet-Induced Renal Steatosis and Age-Related Urinary Sodium Excretion in Mice [PDF]

, 2016
The kidney has a high energy demand and is dependent on oxidative metabolism for ATP production. Accordingly, the kidney is rich in mitochondria, and mitochondrial dysfunction is a common denominator for several renal diseases.
Handschin, Christoph, Kristoffer Svensson, Schnyder, Svenia, Christoph Handschin, Kristoffer Svensson (593634), Svenia Schnyder (3146877), Svensson, Kristoffer, Bettina Cardel (3146880), Svenia Schnyder, Christoph Handschin (184204), Cardel, Bettina, Bettina Cardel, Svensson K, Schnyder S, Handschin C, Cardel B   +15 more
core   +1 more source

Studies on the Efficacy of Cholecalciferol and Derivatives for Stimulating Phytate Utilization in Broilers

, 2002
Studies were conducted to determine the effect of dietary supplementation with cholecalciferol (D3), 1,25-dihydroxycholecalciferol [1,25-(OH)2D3], 1α-hydroxycholecalciferol (1α-OHD3), and 25-hydroxycho-lecalciferol (25-OHD3) on utilization of phytate P ...
H. M. Edwards
core  

EFFECT OF 1α-HYDROXYCHOLECALCIFEROL(1α-OH D3)ON HYPOCALCEMIA FOLLOWING PARATHYROID SURGERY [PDF]

, 1979
A synthetic analogue of active form of Vita mine D (1α-OH D3) was administered to three patients with hypocalcemia following parathyroidectomy for primary hyperparathyroidism and its effect on hypocalcemic and hyperphosphatemic states was discussed ...
川村, 寿一, 岡部, 達士郎, 寺地, 敏郎, 岡田, 裕作, 朴, 勺, 吉田, 修   +5 more
core  

Renal osteodystrophy in nondialysed adolescents. Long-term treatment with 1alpha-hydroxycholecalciferol.

, 2016
The effects of small oral doses (1-2 microgram/day) of 1alpha-hydroxycholecalciferol, given for 1 to 2 years, have been examined in four nondialysed adolescents with chronic renal failure and bone disease. Treatment increased calcium retention and plasma

core   +1 more source

Mecanismos de acción de la vitamina D3, 1-α-hidroxicolecalciferol(1-α-OH-D3,) y 25-hidroxicolecalciferol (25-OH-D3) en gallinas de posturacomercial

, 2014
Mode of action of vitamin D3, 1-α-hydroxycholecalciferol (1-α-OH-D3) and 25-hydroxycholecalciferol (25-OH-D3) in commercial laying hensMecanismos de ação da vitamina D3, 1-α-hidroxicolecalciferol (1-α-OH-D3) e25-hidroxicolecalciferol (25-OH-D3) em ...
González Sepúlveda, Carlos Augusto, Barahona-Rosales, Rolando   +1 more
core   +2 more sources

P450scc (CYP11A1) can hydroxylate vitamin D3 to 20-hydroxycholecalciferol with following sequential metabolism to other hydroxyderivatives [10].

, 2013
P450scc (CYP11A1) can hydroxylate vitamin D3 to 20-hydroxycholecalciferol with following sequential metabolism to other hydroxyderivatives [10].
Michal A. Zmijewski (251101), Andrzej T. Slominski (251089), Zorica Janjetovic (251092), Lawrence M. Pfeffer (280403), Damon A. DeLeon (372060), Robert C. Tuckey (251104), Minh N. Nguyen (251108)   +6 more
core   +1 more source

Comparison of the efficacy of 25-hydroxycholecalciferol and conventional cholecalciferol in the feeding of breeding pigs using blood metabolites, performance and bone data [PDF]

, 2017
In addition to the reproductive performance, the longevity of the sow plays an essen-tial role in the efficiency of piglet production (Pluym et al. 2013).
Schnor, Stella
core   +1 more source

Peroxisome Proliferator-activated Receptor α (PPARα) Induces PPARγ Coactivator 1α (PGC-1α) Gene Expression and Contributes to Thermogenic Activation of Brown Fat

, 2011
Peroxisome proliferator activated receptor α (PPARα) is a distinctive marker of the brown fat phenotype that has been proposed to coordinate the transcriptional activation of genes for lipid oxidation and for thermogenic uncoupling protein 1 in brown ...
Maria Monsalve, Giralt, Marta, Julieta Díaz-Delfín, Villarroya, Francesc, Marta Giralt, Rosell, Meritxell, Francesc Villarroya, Elayne Hondares, Roser Iglesias, Iglesias, Roser, Olmos Buchelt, Yolanda, Díaz Delfín, Julieta, Yolanda Olmos, Hondares, Elayne, Meritxell Rosell, Monsalve, María   +15 more
core   +1 more source