Results 31 to 40 of about 284,169 (292)

SDF-1α predicts poor prognosis in patients with locally advanced esophageal squamous cell carcinoma receiving definitive concurrent chemoradiotherapy

open access: yesBiomedical Journal, 2022
Background: Stromal cell-derived factor-1α (SDF-1α) is a chemokine associated with tumor progression in various types of cancers. The current study aimed to evaluate whether pre-treatment or kinetics of SDF-1α can predict the prognosis in patients with ...
Yen-Hao Chen   +5 more
doaj   +1 more source

Transformer less 1Φ Inverter for Grid-Connected PV Systems with an Optimized Control

open access: yesInternational Journal of Engineering and Technology, 2018
This paper investigates the transformerless single-phase inverter incorporates with the photovoltaic system along with the support of grid voltage. Solar Energy is a Non-Conventional Energy source which is mandatory for power generation due to their immeasurable parade and green pleasant nature. One-cycle control (OCC), Ruggedness and consistency which
T Baldwin Immanuel   +4 more
openaire   +2 more sources

The role of the coactivators PGC-1α and PGC-1β in retina and skeletal muscle [PDF]

open access: yes, 2011
Peroxisome proliferator-activated receptor γ coactivator- 1 (PGC-1) designates a family of coactivators consisting of PGC-1α, PGC-1β and PRC. By associating with transcription factors like nuclear receptors, they induce transcription of target genes that
Egger, A, Egger, Anna Franziska
core   +1 more source

HIF-1α Dependent Upregulation of ZIP8, ZIP14, and TRPA1 Modify Intracellular Zn2+ Accumulation in Inflammatory Synoviocytes

open access: yes, 2021
Intracellular free zinc ([Zn2+]i) is mobilized in neuronal and non-neuronal cells under physiological and/or pathophysiological conditions; therefore, [Zn2+]i is a component of cellular signal transduction in biological systems.
Matsubara, Masaki   +9 more
core   +1 more source

Correlation of VEGF and HIF-1α in breast carcinoma (an immunohistochemical study)

open access: yesIP Journal of Diagnostic Pathology and Oncology, 2020
Introduction: By 2030 the incidence of breast cancer in India will increase to around 200,000 per year. During tumor growth, angiogenesis is induced by many stimuli. Reduced oxygen stimulates hypoxia induced factor 1 alpha (HIF-1?), activating proangiogenic cytokines i.e. vascular endothelial growth factor (VEGF).
openaire   +2 more sources

Study level of Interleukin-1β and Interleukin-2 in women infected with Trichomonas vaginalis parasite

open access: yesAL-QADISIYAH MEDICAL JOURNAL, 2017
The study was conducted on 450 out patients and 30 healthy women, whom have visited the department of infertility at Al-Sadder medical city, Al-Zahra Hospital and in Najaf Province during the period from January till August, 2012. The infection with T.vaginalis in clinical suspected women determine by using the wet amount microscope,the infection women
Basima Sh. Al Gazali   +2 more
openaire   +1 more source

Sleeve gastrectomy and pancreas omentoplasty improved β cell insulin expression and interleukin-1β serum level in non-obese diabetes mellitus rat

open access: yesBali Medical Journal, 2021
Background: Diabetes mellitus is one of the health problems that is growing rapidly today. In Asia, majority of the population are non-obese with Type 2 Diabetes Mellitus (T2DM). Two main defects of T2DM, insulin resistance and impaired insulin secretion due to reduced pancreatic β cells.
Erlangga Dimas   +4 more
openaire   +1 more source

Loss of Renal Tubular PGC-1α Exacerbates Diet-Induced Renal Steatosis and Age-Related Urinary Sodium Excretion in Mice [PDF]

open access: yes, 2016
The kidney has a high energy demand and is dependent on oxidative metabolism for ATP production. Accordingly, the kidney is rich in mitochondria, and mitochondrial dysfunction is a common denominator for several renal diseases.
Handschin, Christoph   +15 more
core   +1 more source

1α,25-dihydroxyvitamin D3 promotes osseointegration of titanium implant via downregulating AGEs/RAGE pathway in T2DM

open access: yesEndocrine Connections, 2018
Diabetes-induced advanced glycation end products (AGEs) overproduction would result in compromised osseointegration of titanium implant and high rate of implantation failure. 1α,25-dihydroxyvitamin D3 (1,25VD3) plays a vital role in osteogenesis, whereas
Tingting Jia   +3 more
doaj   +1 more source

Glucocorticoids Alter CRTC-CREB Signaling in Muscle Cells: Impact on PGC-1α Expression and Atrophy Markers. [PDF]

open access: yesPLoS ONE, 2016
Muscle wasting associated with chronic diseases has been linked to decreased expression of PGC-1α and overexpression of PGC-1α counters muscle loss. CREB, in conjunction with the CREB-regulated transcription coactivator (CRTC2), is a positive modulator ...
Jill A Rahnert   +4 more
doaj   +1 more source

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