Results 111 to 120 of about 21,476,808 (310)

Regulation of MCP-1 chemokine transcription by p53 [PDF]

, 2010
Background Our previous studies showed that the expression of the monocyte-chemoattractant protein (MCP)-1, a chemokine, which triggers the infiltration and activation of cells of the monocyte-macrophage lineage, is abrogated in human papillomavirus (HPV)
Katrin Hacke, Hacke, Katrin, Rincon-Orozco Bladimiro, Simone Y. Siehler, Lisa Wiesmüller, Buchwalter Gilles, Rösl, Frank, Siehler, Simone Y., Siehler, Simone Y, Hacke Katrin, Gilles Buchwalter, Rösl Frank, Bohdan Wasylyk, Buchwalter, Gilles, Wasylyk Bohdan, Wasylyk, Bohdan, Wiesmüller Lisa, Rincon-Orozco, Bladimiro, Siehler Simone Y, Frank Rösl, Bladimiro Rincon-Orozco, Wiesmüller, Lisa   +21 more
core   +1 more source

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

Advanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li, Miao Xu, Heran Li, Huan Jiang, Xin Wang, Lianjun Ma, Ying‐Wei Yang   +6 more
wiley   +1 more source

Crosstalk between Tumor Cells and Macrophages in Stroma Renders Tumor Cells as the Primary Source of MCP-1/CCL2 in Lewis Lung Carcinoma

Frontiers in Immunology, 2015
The chemokine MCP-1/CCL2 is produced by a variety of tumors and plays an important role in cancer progression. We and others previously demonstrated that the primary source of MCP-1 in several mouse tumors, including 4T1 breast cancer, M5076 sarcoma and
Teizo eYoshimura, Mingyong eLiu, Mingyong eLiu, Xin eChen, Xin eChen, Liangzhu eLi, Liangzhu eLi, Ji Ming eWang   +7 more
doaj   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Efecto del 1-Metilciclopropeno (1-MCP) en el comportamiento poscosecha de banano bocadillo (Musa acuminata AA, Simmonds) [PDF]

, 2015
El banano bocadillo o bananito (Musa acuminata AA, Simmonds) es considerado un fruto tropical exótico con alto potencial para ser exportado por Colombia, sin embargo, es altamente perecedero y no cuenta con prácticas adecuadas de manejo de poscosecha, lo
García, Juan Camilo
core  

Number of thumbs (n) of the thumb alignments which were categorized according to the positions of the IP, MCP and CMC joints (IP-MCP-CMC) during maximal performance of PA glide mobilization in both groups.

, 2016
Number of thumbs (n) of the thumb alignments which were categorized according to the positions of the IP, MCP and CMC joints (IP-MCP-CMC) during maximal performance of PA glide mobilization in both groups.
Meng-Tzu Hu (3094632), Fong-Chin Su (234839), Ar-Tyan Hsu (3094635)   +2 more
core   +1 more source

Fine‐Tuned Regulation of mRNA Translation and Transport by STAU2 Condensate Facilitates Neuronal Development and Plasticity

Advanced Science, EarlyView.
STAU2 undergoes phase separation to form dynamic condensates that package target mRNAs and deliver them to the distal ends of growing neuronal dendrites. STAU2 condensates stabilize embedded mRNAs and repress their translation. Synaptic activity bidirectionally remodels STAU2 condensates, coordinating local translation of STAU2‐associated mRNAs ...
Shijing Huang, Yuanyuan Chu, Ruiqian Zhao, Siyu Li, Yu Feng, Hongdan Zheng, Yunli Xie, Tong Wang, Wenyu Wen   +8 more
wiley   +1 more source

Monocyte chemoattractant protein-1: a proinflammatory cytokine elevated in sarcopenic obesity

Clinical Interventions in Aging, 2015
Jun Pei Lim,1,2 Bernard P Leung,3 Yew Yoong Ding,1,2 Laura Tay,1,2 Noor Hafizah Ismail,2,4 Audrey Yeo,2 Suzanne Yew,2 Mei Sian Chong1,2 1Department of Geriatric Medicine, 2Institute of Geriatrics and Active Ageing, 3Department of Rheumatology, Allergy ...
Lim JP, Leung BP, Ding YY, Tay L, Ismail NH, Yeo A, Yew S, Chong MS   +7 more
doaj  

Defect‐Functionalization‐Mediated Tunneling Drives Nonlinear Photoemission in Perovskites

Advanced Science, EarlyView.
This cover illustration depicts CsPbBr3 perovskite nanocrystals embedded with functionalized defect vacancies, where electrons migrate through defect‐mediated pathways and emit as lightning‐like beams. The imagery visualizes the core discovery of our work—defect‐functionalization‐mediated tunneling enabling nonlinear photoemission, where deep‐level ...
Hang Ren, Xi Zhang, Yicheng Wang, Shuai Wang, Zhi Wang, Yumeng Li, Jikai Yang, Xin Wang, Weijun Chen, Yining Mu   +9 more
wiley   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source