Results 111 to 120 of about 107,863,892 (308)
Enforced effect of tk-MCP-1 fusion gene in ovarian cancer
, 2012 Objective The efficiency of HSV-tk/GCV system is not high because of insufficient gene transfer and incompletely initiative of host antineoplastic potency.
Kong Beihua +7 more
core +1 more source
Advanced Science, EarlyView.An inhalable, nanoengineered herbal therapy achieves protection against acute radiation‐induced lung injury via self‐assembled nanomicelle‐mediated pulmonary targeting and a previously unrecognized dual mechanism that attenuates oxidative stress while inhibiting ferroptosis in alveolar epithelial cells.
Li Quan +11 more
wiley +1 more source
MCP-1 binds to oxidized LDL and is carried by lipoprotein(a) in human plasma
Journal of Lipid Research, 2013 Lipoprotein oxidation plays an important role in pathogenesis of atherosclerosis. Oxidized low density lipoprotein (OxLDL) induces profound inflammatory responses in vascular cells, such as production of monocyte chemoattractant protein-1 (MCP-1 ...
Philipp Wiesner +14 more
doaj +1 more source
Advanced Science, EarlyView.CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley +1 more source
Serum monocyte chemoattractant protein-1 is a biomarker in patients with diabetes and periodontitis
Indian Journal of Endocrinology and Metabolism, 2014 Introduction: The role of serum Monocyte Chemoattractant Protein-1 (MCP-1) as a biomarker of periodontitis is well documented; however, its role in diabetic patients with periodontitis is unknown.
Preethi Radhakrishnan +4 more
doaj +1 more source
Advanced Science, EarlyView.Rapid cooling after device annealing regulates the CdS/CZTS heterojunction and Mo/CZTS back contact, suppressing interfacial recombination and modifying the interfacial MoS2 layer, thereby enabling a 15.9% indoor PCE in pure‐sulfide CZTS solar cells.
Achmad Nasyori +16 more
wiley +1 more source
Engineered Transformer Base Editor with Enhanced Editing Efficiency
Advanced Science, EarlyView.A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen +5 more
wiley +1 more source
Murine cytomegalovirus infection markedly reduces serum MCP-1 levels in MCP-1 transgenic mice
, 2006 Monocyte chemoattractant protein-1 (MCP-1) is a pro-inflammatory chemokine believed to play a major role in atherogenesis. Injured endothelial cells express MCP-1, which attracts monocytes to the blood vessel wall and leads to the formation of atheromas.
Froberg, M. Kent +4 more
core +1 more source
Research advances of CCR2/MCP-1 and kidney diseases
, 2021 As a major receptor of monocyte chemotactic protein-1（MCP-1）,CC chemokine receptor 2（CCR2）can specifically conjugate to MCP-1,transfer signals into cytoplasm, mediate the chemotaxis and activation of monocytes and macrophages and promote the occurrence ...
Shen Yan-jie +4 more
core
Advanced Science, EarlyView.This work employs a hybrid hole transport layer to enhance hole transport efficiency, resulting in improved performance for the final device. It achieves an external quantum efficiency of 6.68%, a circularly polarized electroluminescence asymmetry factor of 0.026, and a high luminance of 14,370 cd/cm2, representing the highest luminance reported to ...
Fengqi Qiu +8 more
wiley +1 more source