Results 161 to 170 of about 2,086 (198)

Trans-10-hydroxy-2-decenoic acid protects against LPS-induced neuroinflammation through FOXO1-mediated activation of autophagy

European Journal of Nutrition, 2019
Neuroinflammation is thought to be associated with the pathogenesis of a series of neurodegenerative diseases. We have previously reported that royal jelly (RJ) has an anti-inflammatory effect on microglial BV-2 cells. However, components contributing to the effect of RJ were largely unexplored.
Mengmeng You, Zhuoning Miao, Jing Tian, Fuliang Hu   +3 more
openaire   +2 more sources

Biosynthesis of 10-Hydroxy-2-decenoic Acid through a One-Step Whole-Cell Catalysis

Journal of Agricultural and Food Chemistry
10-Hydroxy-2-decenoic acid (10-HDA) is an important component of royal jelly, known for its antimicrobial, anti-inflammatory, blood pressure-lowering, and antiradiation effects. Currently, 10-HDA biosynthesis is limited by the substrate selectivity of acyl-coenzyme A dehydrogenase, which restricts the technique to a two-step process.
Ke Fang, Ziting Xu, Lu Yang, Quan Cui, Bowen Du, Huijing Liu, Ruiming Wang, Piwu Li, Jing Su, Junqing Wang   +9 more
openaire   +2 more sources

Separation and determination of 10-hydroxy-2-decenoic acid in royal jelly by capillary electrophoresis

Chromatographia, 1995
The application of capillary electrophoresis (CE) to the separation and determination of the active ingredient, 10-hydroxy-2-decenoic acid, in royal jelly with direct on-column UV detection at 214 nm is described. Using a cathodic injection and anodic detection scheme, 10-hydroxy-2-decenoic acid (10-HDA) was separated and detected in less than 10 min ...
null Li Jia, H. X. Zhang, X. L. Kou, Z. D. Hu   +3 more
openaire   +1 more source

10-Hydroxy-2-decenoic Acid as an Antimicrobial Agent in Draft Keg-Conditioned Wheat Beer

Journal of the American Society of Brewing Chemists, 2010
In nature, 10-hydroxy-2-decenoic acid (10-HDA), an important unsaturated fatty acid, is only available in royal jelly.
Shanshan Li, Zhumao Jiang, Leo Thamm, Guangtian Zhou   +3 more
openaire   +1 more source

ChemInform Abstract: Synthesis of (E)‐9‐Oxo‐2‐decenoic Acid and (E)‐10‐Hydroxy‐2‐decenoic Acid

ChemInform, 1992
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
I. R. TREHEN, R. VIG, V. SINGH, S. SHARMA, G. L. KAD   +4 more
openaire   +1 more source

Determination of 10‐Hydroxy‐2‐Decenoic Acid of Royal Jelly Using Near‐Infrared Spectroscopy Combined with Chemometrics

Journal of Food Science, 2019
Abstract A rapid quantitative analysis model for determining the hydroxy‐2‐decenoic acid (10‐HDA) content of royal jelly based on near‐infrared spectroscopy combining with PLS has been developed. Firstly, near‐infrared spectra of 232 royal jelly samples with different 10‐HDA concentrations (0.35% to 2.44%) were be
Xinhao Yang, Yuanpeng Li, Lei Wang, Liqun Li, Liu Guo, Furong Huang, Hongxia Zhao   +6 more
openaire   +2 more sources

Purification and identification of 10-hydroxy-2-decenoic acid from pure royal jelly

2004
The chemical nature of the royal jelly (RJ) has received considerable attention over the past 20 years. Genc and Aslan reported the determination of Trans-10-hydroxy-2-decenoic acid (10-HDA) content in pure Royal Jelly and royal jelly products by column liquid chromatography. Antinelli et al.
Honary, S, Ebrahimi, P, Changizi Sh, Changizi Sh, Nozadi, Z   +3 more
openaire   +1 more source

[The research of 10-hydroxy-2-decenoic acid on experiment hyperlipoidemic rat].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2004
To study the pharmacological effect of 10-hydroxy-2-decenoic acid(10-HDA) in experiment hyperlipoidemic rat.Preventive and therapeutic effects of 10-HDA were tested on hyperlioidemic rat model induced by high fat food.10-HDA could reduce the content of TC, TG and beta-lioprotein, raise the content of HDL, which showed 10-HDA had preventive and ...
Donghui, Xu, Xueting, Mei, Shibo, Xu
openaire   +1 more source

10-Hydroxy-2-decenoic acid attenuates nonalcoholic fatty liver disease by activating AMPK-α signaling pathway

Biochemical Pharmacology
Nonalcoholic fatty liver disease (NAFLD) originates from metabolic dysfunctions, is one of the most commonly encountered liver disorders worldwide, characterized by ectopic lipid deposition within hepatocytes, accompanied by hepatocellular injury and necroinflammation. Currently, NAFLD has very few treatment options.
Minyi Tang, Xinzi Wang, Shuai Wang, Chaofeng Xing, Qihua Xu, Yunping Mu, Xiaoli Wu, Zijian Allan Zhao, Fanghong Li   +8 more
openaire   +2 more sources

10‐Hydroxy‐2‐decenoic acid prevents ultraviolet A‐induced damage and matrix metalloproteinases expression in human dermal fibroblasts

Journal of the European Academy of Dermatology and Venereology, 2012
AbstractBackground  10‐Hydroxy‐2‐decenoic acid (10‐HDA) is a major fatty acid component of royal jelly, which has been reported to have a variety of beneficial pharmacological characteristics. However, the effects of 10‐HDA on skin photoageing and its potential mechanism of action are unclear.Objective  We investigated the protective effects of 10‐HDA ...
Jinfen, Zheng, Wei, Lai, Guoxing, Zhu, Miaojian, Wan, Jian, Chen, Yan, Tai, Chun, Lu   +6 more
openaire   +2 more sources