Results 241 to 250 of about 253,664 (304)

De Novo Heterozygous ZFX Frameshift Variant in a Female With an X‐Linked Neurodevelopmental Disorder

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Germline ZFX variants are associated with an X‐linked neurodevelopmental disorder, with 14 males and 16 females reported to date. We describe a 20‐year‐old female with a heterozygous ZFX frameshift variant, p.(Met666Valfs*2), identified by genome sequencing, previously reported in an affected male.
Iftekhar A. Showpnil, Allison Daley, Emily R. Sites, Shayne M. Plourde, Jesse M. Hunter, Dennis W. Bartholomew, April N. Lehman, Daniel C. Koboldt, Rolf W. Stottmann   +8 more
wiley   +1 more source

Improved resolution of microbial diversity in deep-sea surface sediments using PacBio long-read 16S rRNA gene sequencing. [PDF]

mSphere
Gao J, Wang Z, Deng W, Sa B, Chen X, Cai R, Yan Y, Jiao N, Leung EL-H, Liu D, Yan W.   +10 more
europepmc   +1 more source

Strengths and Limitations of 16S rRNA Gene Amplicon Sequencing in Revealing Temporal Microbial Community Dynamics

, 2014
Rachel Poretsky, Luis M. Rodriguez‐R, Chengwei Luo, Despina Tsementzi, Konstantinos T. Konstantinidis   +4 more
openalex   +2 more sources

A Novel Antimalarial Agent that Inhibits Protein Synthesis in Plasmodium falciparum

Angewandte Chemie International Edition, EarlyView.
Compound 31 represents a promising avenue for the development as an antimalarial agent with a potent activity profile (PfNF54 IC50 ± s.d. = 3.9 ± 0.4 nM). It has a novel mode of action by binding to cytosolic ribosomal subunits, thereby inhibiting protein synthesis in the parasite.
Patricia Bravo, Eleonora Diamanti, Mostafa M. Hamed, Lorenzo Bizzarri, Natalie Wiedemar, Armin Passecker, Nicolas M. B. Brancucci, Anna Albisetti, Christin Gumpp, Boris Illarionov, Markus Fischer, Matthias Witschel, Tobias Schehl, Hannes Hahne, Pascal Mäser, Matthias Rottmann, Anna K. H. Hirsch   +16 more
wiley   +1 more source

Pulmonary Nocardiosis Caused by Nocardia sputorum Identified via 16S rRNA Gene Sequencing: A Case Report. [PDF]

Cureus
Irifune S, Ide S, Koga S, Mine K, Sugasaki N, Kosai K, Fukuda M, Yanagihara K, Mukae H.   +8 more
europepmc   +1 more source

Antibiotic Sensitivity of Vibrio spp. and Shewanella algae Isolated From Brood and Egg of Mud Crab Hatchery

Animal Research and One Health, EarlyView.
Vibrio alginolyticus NBRC 15630, Vibrio parahaemolyticus ATCC 17802, Shewanella algae DW01, and Shewanella algae ATCC 51192 bacterial strains were found in the Mud crab brood and egg samples. All isolates were found to be sensitive to cefotaxime, chloramphenicol, gentamicin, and nitrofurantoin antibiotics.
Abul Farah Md. Hasanuzzaman, Nurunnahar Nadira, Anup Sardar, Sabia Islam   +3 more
wiley   +1 more source

Quantifying variation across 16S rRNA gene sequencing runs in human microbiome studies. [PDF]

Appl Microbiol Biotechnol
Hoisington AJ, Stamper CE, Ellis JC, Lowry CA, Brenner LA.   +4 more
europepmc   +1 more source

Dietary Baicalin Supplementation Can Enhance the Growth Performance of Weaned Piglets and Maintain the Intestinal Barrier Integrity

Animal Research and One Health, EarlyView.
This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao, Jie Liu, Rui Yang, Xizhen Fan, Cheng Liang, Xin'e Shi, Jianjun Jin   +6 more
wiley   +1 more source

Profiling bacterial communities in feedlot cattle affected with bovine foot rot and bovine digital dermatitis lesions using 16S rRNA gene sequencing and quantitative real-time PCR. [PDF]

BMC Microbiol
Pyakurel S, Caddey BJ, Dias AP, De Buck J, Morck DW, Orsel K.   +5 more
europepmc   +1 more source

Prokaryotic Community Structures in a Thermophilic Anaerobic Digestion Reactor Converting Poly( l -Lactic Acid) for a Long Period Revealed by 16S rRNA Gene Amplicon Sequencing

, 2019
Takeshi Yamada, Masako Hamada, Misaki Kurobe, Jun Harada, Surya Giri, Hideto Tsuji, Hiroyuki Daimon   +6 more
openalex   +1 more source